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| | ATP5PF | ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa) |
| | GPX7 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (151 aa) |
| | NDUFS5 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. (106 aa) |
| | LOC102999929 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa) |
| | LOC103015043 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa) |
| | POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) |
| | LOC103003421 | Cytochrome c oxidase subunit 7A1, mitochondrial. (80 aa) |
| | LOC103010509 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (249 aa) |
| | POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1258 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa) |
| | REST | RE1-silencing transcription factor isoform X1. (1068 aa) |
| | GRIA1 | Glutamate receptor 1 isoform X1. (906 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1253 aa) |
| | NDUFA12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | POLR2A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1963 aa) |
| | DLG4 | Disks large homolog 4 isoform X1; Belongs to the MAGUK family. (754 aa) |
| | DNAH2 | Dynein heavy chain 2, axonemal. (4424 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | VDAC2 | Voltage-dependent anion-selective channel protein 2 isoform X3. (309 aa) |
| | PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4 isoform X1. (1358 aa) |
| | LOC103017759 | Cytochrome c oxidase subunit 7A-related protein, mitochondrial. (114 aa) |
| | ATP5F1C | ATP synthase subunit gamma. (298 aa) |
| | POLR2C | DNA-directed RNA polymerase II subunit RPB3 isoform X1. (275 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (472 aa) |
| | AP2S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa) |
| | KLC3 | Kinesin light chain 3. (505 aa) |
| | LOC103019426 | Cytochrome c oxidase subunit 7A2, mitochondrial. (83 aa) |
| | BAX | Apoptosis regulator BAX. (192 aa) |
| | BBC3 | Bcl-2-binding component 3. (140 aa) |
| | RB1CC1 | RB1-inducible coiled-coil protein 1 isoform X1. (1589 aa) |
| | NDUFA7 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. (113 aa) |
| | LOC103010896 | Cytochrome b-c1 complex subunit 1, mitochondrial isoform X1. (481 aa) |
| | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X2. (435 aa) |
| | NDUFA11 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11. (141 aa) |
| | CREB3L3 | Cyclic AMP-responsive element-binding protein 3-like protein 3. (457 aa) |
| | LOC103017687 | Cytochrome c oxidase subunit 7B, mitochondrial-like. (69 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | ATP5PB | ATP synthase F(0) complex subunit B1, mitochondrial. (277 aa) |
| | CLTB | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (175 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa) |
| | NDUFA9 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial. (377 aa) |
| | LOC103006928 | Cytochrome b-c1 complex subunit 9. (64 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa) |
| | NDUFV1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa) |
| | NDUFS8 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1. (213 aa) |
| | KLC2 | Kinesin light chain 2 isoform X1. (622 aa) |
| | NRBF2 | Nuclear receptor-binding factor 2 isoform X1. (288 aa) |
| | AP2A2 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (922 aa) |
| | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (376 aa) |
| | NDUFS2 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X1; Belongs to the complex I 49 kDa subunit family. (462 aa) |
| | LOC103003361 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | SDHC | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (169 aa) |
| | KCNJ10 | ATP-sensitive inward rectifier potassium channel 10. (379 aa) |
| | VDAC1 | Voltage-dependent anion-selective channel protein 1. (283 aa) |
| | LOC103013686 | Huntingtin isoform X1. (2391 aa) |
| | SLC25A31 | ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa) |
| | LOC103019192 | Tubulin beta-3 chain; Belongs to the tubulin family. (816 aa) |
| | NDUFC1 | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. (76 aa) |
| | LOC103015443 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial. (169 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | NDUFV3 | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1. (477 aa) |
| | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | SLC25A6 | ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa) |
| | ULK2 | Serine/threonine-protein kinase ULK2 isoform X1. (961 aa) |
| | DCTN6 | Dynactin subunit 6 isoform X1. (229 aa) |
| | LOC102999698 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (457 aa) |
| | ATG2A | Autophagy-related protein 2 homolog A isoform X1. (1928 aa) |
| | LOC103010848 | Cytochrome c oxidase subunit 8A, mitochondrial. (69 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa) |
| | POLR2G | DNA-directed RNA polymerase II subunit RPB7. (172 aa) |
| | DNAH1 | Dynein heavy chain 1, axonemal. (4265 aa) |
| | PSMA1 | Proteasome subunit alpha type. (263 aa) |
| | SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa) |
| | CASP9 | Caspase-9 isoform X1; Belongs to the peptidase C14A family. (414 aa) |
| | DNAH9 | Dynein heavy chain 9, axonemal. (4201 aa) |
| | DNAH6 | LOW QUALITY PROTEIN: dynein heavy chain 6, axonemal. (4154 aa) |
| | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1. (960 aa) |
| | PSMC5 | 26S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa) |
| | KLC1 | Kinesin light chain 1 isoform X1. (652 aa) |
| | TFAM | Transcription factor A, mitochondrial. (240 aa) |
| | RCOR1 | REST corepressor 1 isoform X1. (352 aa) |
| | LOC103010463 | Cytochrome b-c1 complex subunit 10-like. (72 aa) |
| | ATP5MC1 | ATP synthase F(0) complex subunit C1, mitochondrial; Belongs to the ATPase C chain family. (136 aa) |
| | POLR2E | DNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa) |
| | NDUFS7 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Belongs to the complex I 20 kDa subunit family. (216 aa) |
| | ATP5F1D | ATP synthase subunit delta, mitochondrial. (131 aa) |
| | NDUFB6 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 isoform X1. (128 aa) |
| | DNAI1 | Dynein intermediate chain 1, axonemal. (712 aa) |
| | NDUFB2 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. (105 aa) |
| | NRF1 | LOW QUALITY PROTEIN: nuclear respiratory factor 1. (501 aa) |
| | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform X1. (116 aa) |
| | CREB3L2 | Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | LOC103012872 | Beclin-1 isoform X1. (473 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (534 aa) |
| | LOC103006874 | Huntingtin-associated protein 1-like. (636 aa) |
| | CASP3 | Caspase-3; Belongs to the peptidase C14A family. (275 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa) |
| | NDUFA8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8. (206 aa) |
| | SLC25A4 | ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | SLC25A5 | ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (283 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | CREB3L4 | Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (395 aa) |
| | ATG2B | Autophagy-related protein 2 homolog B isoform X1. (2096 aa) |
| | LOC103013818 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa) |
| | LOC103015962 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) |
| | GPX6 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (264 aa) |
| | TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | LOC103020122 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | ATG101 | Autophagy-related protein 101. (218 aa) |
| | SP1 | Transcription factor Sp1. (787 aa) |
| | ATP5MC2 | ATP synthase F(0) complex subunit C2, mitochondrial; Belongs to the ATPase C chain family. (142 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa) |
| | DCTN2 | Dynactin subunit 2 isoform X1. (408 aa) |
| | KIF5A | Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa) |
| | NDUFA4L2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2. (87 aa) |
| | PSMC4 | 26S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (351 aa) |
| | MAP3K10 | Mitogen-activated protein kinase kinase kinase 10. (645 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | LOC103011737 | Cytochrome c oxidase subunit 7B2, mitochondrial. (81 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1131 aa) |
| | PSMC1 | 26S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (256 aa) |
| | SLC1A2 | Amino acid transporter. (574 aa) |
| | CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa) |
| | ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (551 aa) |
| | AMBRA1 | Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1310 aa) |
| | PSMC3 | 26S proteasome regulatory subunit 6A; Belongs to the AAA ATPase family. (423 aa) |
| | ULK1 | Serine/threonine-protein kinase ULK1. (873 aa) |
| | LOC103005093 | Cytochrome c oxidase subunit 6B2. (87 aa) |
| | NDUFS3 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial isoform X1; Belongs to the complex I 30 kDa subunit family. (267 aa) |
| | NDUFA3 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3. (84 aa) |
| | CREBBP | CREB-binding protein isoform X1. (2444 aa) |
| | NDUFB4 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. (129 aa) |
| | NDUFB7 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. (137 aa) |
| | VDAC3 | Voltage-dependent anion-selective channel protein 3 isoform X1. (282 aa) |
| | LOC103018216 | Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | BECN2 | Beclin-2. (432 aa) |
| | DNALI1 | Axonemal dynein light intermediate polypeptide 1. (258 aa) |
| | GRIN1 | Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa) |
| | POLR2D | DNA-directed RNA polymerase II subunit RPB4. (104 aa) |
| | KIF5C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa) |
| | NDUFB11 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial isoform X1. (173 aa) |
| | ATP5PO | ATP synthase subunit O, mitochondrial. (213 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa) |
| | LOC103008559 | Cytochrome c oxidase subunit 6A, mitochondrial. (108 aa) |
| | GRIA2 | Glutamate receptor 2 isoform X9. (940 aa) |
| | PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa) |
| | LOC103010006 | Cytochrome c oxidase subunit 8C, mitochondrial. (74 aa) |
| | LOC103019246 | Cytochrome c oxidase subunit 7B, mitochondrial. (80 aa) |
| | GPX2 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa) |
| | DNAL1 | Dynein light chain 1, axonemal. (190 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | NDUFA10 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (360 aa) |
| | AP2A1 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (983 aa) |
| | TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (485 aa) |
| | ATP5F1E | ATP synthase subunit epsilon, mitochondrial. (51 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (220 aa) |
| | TAF4 | Transcription initiation factor TFIID subunit 4. (733 aa) |
| | ATP5PD | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa) |
| | DNAI2 | Dynein intermediate chain 2, axonemal. (608 aa) |
| | DNAH17 | Dynein heavy chain 17, axonemal. (4463 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12. (434 aa) |
| | TBP | TATA-box-binding protein isoform X1. (317 aa) |
| | SOD2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | DCTN5 | Dynactin subunit 5. (182 aa) |
| | LOC103006136 | Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa) |
| | STX1A | syntaxin-1A; Belongs to the syntaxin family. (259 aa) |
| | HIP1 | Huntingtin-interacting protein 1 isoform X1. (1037 aa) |
| | POLR2J | DNA-directed RNA polymerase II subunit RPB11-a. (117 aa) |
| | WIPI2 | WD repeat domain phosphoinositide-interacting protein 2. (441 aa) |
| | IFT57 | Intraflagellar transport protein 57 homolog. (427 aa) |
| | ACTR1A | Alpha-centractin. (376 aa) |
| | NDUFB8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa) |
| | PPARGC1A | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (803 aa) |
| | NDUFC2 | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa) |
| | LOC103007708 | RE1-silencing transcription factor-like. (871 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | LOC103008872 | RE1-silencing transcription factor-like. (326 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | LOC103007507 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (417 aa) |
| | DNAH5 | Dynein heavy chain 5, axonemal. (4623 aa) |
| | LOC103012637 | Cytochrome b-c1 complex subunit 8. (82 aa) |
| | GPX3 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (226 aa) |
| | DCTN4 | Dynactin subunit 4 isoform X1. (467 aa) |
| | NDUFB9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Belongs to the complex I LYR family. (179 aa) |
| | LOC103012727 | Voltage-dependent anion-selective channel protein 3-like. (264 aa) |
| | DCTN1 | Dynactin subunit 1 isoform X1. (1281 aa) |
| | DNAL4 | Dynein light chain. (105 aa) |
| | NDUFA6 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 isoform X1; Belongs to the complex I LYR family. (143 aa) |
| | UCP1 | Mitochondrial brown fat uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (274 aa) |
| | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9. (223 aa) |
| | DNAH10 | LOW QUALITY PROTEIN: dynein heavy chain 10, axonemal. (4517 aa) |
| | LOC102998746 | Cytochrome b-c1 complex subunit 2, mitochondrial; Belongs to the peptidase M16 family. (453 aa) |
| | LOC103016559 | ATP synthase F(0) complex subunit B1, mitochondrial-like. (187 aa) |
| | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 isoform X1. (429 aa) |
| | AP2B1 | AP complex subunit beta. (951 aa) |
| | LOC103017780 | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa) |
| | LOC103001251 | Cytochrome c oxidase subunit 8C, mitochondrial-like. (70 aa) |
| | NDUFB3 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (98 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | NDUFS1 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (727 aa) |
| | DNAH7 | Dynein heavy chain 7, axonemal. (4014 aa) |
| | LOC102999215 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ATP5MC3 | ATP synthase F(0) complex subunit C3, mitochondrial; Belongs to the ATPase C chain family. (141 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (492 aa) |
| | TBPL1 | TATA box-binding protein-like protein 1. (186 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 isoform X3. (1219 aa) |
| | NDUFS6 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (124 aa) |
| | SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (664 aa) |
| | NDUFA4 | Cytochrome c oxidase subunit NDUFA4. (82 aa) |
| | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6. (389 aa) |
| | SLC1A3 | Amino acid transporter. (542 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa) |
| | ATG14 | Beclin 1-associated autophagy-related key regulator. (492 aa) |
| | PSMC6 | 26S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | ACTR10 | Actin-related protein 10; Belongs to the actin family. (417 aa) |
| | TBPL2 | TATA box-binding protein-like protein 2. (449 aa) |
| | LOC103013789 | Cytochrome c oxidase subunit 7C, mitochondrial. (63 aa) |
| | TGM2 | Protein-glutamine gamma-glutamyltransferase 2. (687 aa) |
| | LOC103019629 | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X1. (171 aa) |
| | LOC102997662 | Tubulin beta chain-like; Belongs to the tubulin family. (449 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5 isoform X1. (502 aa) |
| | TRAF2 | TNF receptor-associated factor. (412 aa) |
| | NDUFA2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | POLR2H | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (851 aa) |
| | AP2M1 | AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (437 aa) |
| | NDUFB5 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform X1. (189 aa) |
| | NDUFA13 | LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (164 aa) |
| | NDUFS4 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform X1. (175 aa) |
| | GPX8 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa) |
| | GRIN2B | Glutamate receptor ionotropic, NMDA 2B. (1491 aa) |
| | NDUFV2 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. (232 aa) |
| | TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (374 aa) |
| | LOC103019471 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa) |
| | LOC103018473 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa) |
| | KIF5B | Kinesin-1 heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1036 aa) |
| | CREB3 | Cyclic AMP-responsive element-binding protein 3 isoform X1. (371 aa) |
| | CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (255 aa) |
| | LOC103015197 | Cytochrome c oxidase subunit 5B, mitochondrial. (129 aa) |
| | ACTR1B | Beta-centractin isoform X1. (376 aa) |
| | PSMA8 | Proteasome subunit alpha type. (265 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
| | LOC103003865 | Cytochrome c oxidase subunit 5A, mitochondrial isoform X1. (199 aa) |
| | TAF4B | Transcription initiation factor TFIID subunit 4B isoform X1. (862 aa) |
| | DNAH8 | Dynein heavy chain 8, axonemal. (4618 aa) |
| | SIN3A | Paired amphipathic helix protein Sin3a. (1274 aa) |
| | KLC4 | Kinesin light chain 4 isoform X1. (622 aa) |
| | TUBB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | GPX1 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (238 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa) |
| | LOC103019847 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | TUBB4B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (379 aa) |
| | LOC103003514 | Cytochrome c1, heme protein, mitochondrial. (260 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa) |
| | PSMD7 | LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 7. (326 aa) |
| | GRM5 | Metabotropic glutamate receptor 5 isoform X2. (942 aa) |
| | TUBB4A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | DCTN3 | Dynactin subunit 3 isoform X1. (199 aa) |
| | NDUFB10 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 isoform X1. (181 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2153 aa) |
| | DNAH11 | Dynein heavy chain 11, axonemal. (4188 aa) |
| | ADRM1 | Proteasomal ubiquitin receptor ADRM1. (407 aa) |
| | WIPI1 | WD repeat domain phosphoinositide-interacting protein 1 isoform X1. (398 aa) |
| | POLR2F | DNA-directed RNA polymerases I, II, and III subunit RPABC2. (115 aa) |
| | EP300 | Histone acetyltransferase p300. (2445 aa) |
| | DNAH3 | Dynein heavy chain 3, axonemal. (4072 aa) |
| | GRIA4 | Glutamate receptor 4 isoform X1. (632 aa) |
| | DNAH12 | Dynein heavy chain 12, axonemal. (3961 aa) |
