STRINGSTRING
LOC103014668 LOC103014668 ARHGEF26 ARHGEF26 LOC103001311 LOC103001311 CYFIP2 CYFIP2 CYTH4 CYTH4 TXN2 TXN2 HSP90B1 HSP90B1 ANXA2 ANXA2 MAP2K1 MAP2K1 PIK3C2B PIK3C2B PFN1 PFN1 GSDMD GSDMD PTPRC PTPRC ACBD3 ACBD3 MYO6 MYO6 KLC3 KLC3 CYTH2 CYTH2 BAX BAX IRAK4 IRAK4 RHOA RHOA FYCO1 FYCO1 DNM2 DNM2 MAP2K7 MAP2K7 MAP2K2 MAP2K2 PFN3 PFN3 PIK3CD PIK3CD GAPDH GAPDH TNFRSF1A TNFRSF1A PIK3CB PIK3CB FADD FADD RELA RELA KLC2 KLC2 HRAS HRAS LOC103017407 LOC103017407 LOC103003361 LOC103003361 TLR5 TLR5 SKP1 SKP1 PIK3C3 PIK3C3 IL18 IL18 NFKB1 NFKB1 TCF7L2 TCF7L2 CASP7 CASP7 FBXO22 FBXO22 VPS39 VPS39 RHOG RHOG LOC103018270 LOC103018270 EXOC2 EXOC2 MAP2K3 MAP2K3 AHNAK AHNAK LOC103010163 LOC103010163 CDC42 CDC42 TAB3 TAB3 MAP2K4 MAP2K4 TCF7L1 TCF7L1 ARPC5 ARPC5 KPNA1 KPNA1 NAIP NAIP ARL17A ARL17A KLC1 KLC1 AKT1 AKT1 DYNLL2 DYNLL2 EXOC4 EXOC4 FLNC FLNC WASL WASL PODXL PODXL MAPK10 MAPK10 LOC103013898 LOC103013898 CASP3 CASP3 S100A10 S100A10 TLR4 TLR4 TXN TXN MAPK8 MAPK8 RHOH RHOH TLR6 TLR6 HSP90AA1 HSP90AA1 DYNC1H1 DYNC1H1 RAB7A RAB7A RAB5B RAB5B NCKAP1L NCKAP1L CXCL8 CXCL8 AKT2 AKT2 PLEKHM1 PLEKHM1 VPS18 VPS18 RIPK3 RIPK3 NFKBIA NFKBIA PIK3CG PIK3CG TRAF6 TRAF6 MYL5 MYL5 RAB9A RAB9A PKN1 PKN1 STX10 STX10 RIPK2 RIPK2 AKT3 AKT3 DYNLRB2 DYNLRB2 LOC103013736 LOC103013736 CYFIP1 CYFIP1 RAB5A RAB5A PAK3 PAK3 DYNC1I2 DYNC1I2 TIRAP TIRAP PFN4 PFN4 RHOB RHOB LOC103019676 LOC103019676 RILP RILP IL6 IL6 DYNLL1 DYNLL1 DYNLT3 DYNLT3 FOS FOS LY96 LY96 RAB9B RAB9B ELMO2 ELMO2 CSE1L CSE1L IRAK1 IRAK1 MAP2K6 MAP2K6 EXOC7 EXOC7 CYTH1 CYTH1 ACTG1 ACTG1 DYNLT1 DYNLT1 MYLPF MYLPF MAPK3 MAPK3 LOC103004444 LOC103004444 MYL10 MYL10 ARPC1B ARPC1B RAC1 RAC1 ACTB ACTB ARPC1A ARPC1A BAK1 BAK1 CYTH3 CYTH3 KPNA4 KPNA4 GCC2 GCC2 CHUK CHUK VPS41 VPS41 RALA RALA ARPC2 ARPC2 PFN2 PFN2 RAB7B RAB7B MYC MYC TAB1 TAB1 MYL2 MYL2 ARPC3 ARPC3 VPS33A VPS33A TLR2 TLR2 DYNC2LI1 DYNC2LI1 NCKAP1 NCKAP1 LOC103017780 LOC103017780 CASP8 CASP8 LOC102999215 LOC102999215 LEF1 LEF1 BIRC2 BIRC2 DYNC2H1 DYNC2H1 LOC103012084 LOC103012084 NLRC4 NLRC4 MYD88 MYD88 BIRC3 BIRC3 CASP1 CASP1 LOC103010734 LOC103010734 LOC103010250 LOC103010250 BCL2 BCL2 FLNB FLNB ARPC4 ARPC4 RAF1 RAF1 BRK1 BRK1 ARF6 ARF6 RHOJ RHOJ MYL9 MYL9 EXOC5 EXOC5 DYNLRB1 DYNLRB1 CTNNB1 CTNNB1 KPNA3 KPNA3 HSP90AB1 HSP90AB1 TNF TNF TRAF2 TRAF2 CD14 CD14 LOC102999798 LOC102999798 ARPC5L ARPC5L PIK3C2G PIK3C2G ELMO1 ELMO1 ROCK2 ROCK2 VPS16 VPS16 DYNC1I1 DYNC1I1 MAP3K7 MAP3K7 M6PR M6PR MAPK1 MAPK1 VPS11 VPS11 TAB2 TAB2 IL1B IL1B TNFSF10 TNFSF10 SNX33 SNX33 LOC103007269 LOC103007269 MAPK14 MAPK14 KLC4 KLC4 DYNC1LI2 DYNC1LI2 TRADD TRADD AHNAK2 AHNAK2 LOC103007471 LOC103007471 PIK3CA PIK3CA SNX18 SNX18 MAPK13 MAPK13 FHOD1 FHOD1 FA2H FA2H ARF1 ARF1 NLRP3 NLRP3 NOD1 NOD1 PIK3C2A PIK3C2A LOC103003848 LOC103003848 FLNA FLNA SNX9 SNX9 PAK1 PAK1 DYNC1LI1 DYNC1LI1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103014668Transcription factor AP-1; Belongs to the bZIP family. (253 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (870 aa)
LOC103001311Transcription factor AP-1-like. (199 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1287 aa)
CYTH4Cytohesin-4. (423 aa)
TXN2Thioredoxin, mitochondrial. (166 aa)
HSP90B1Endoplasmin. (805 aa)
ANXA2Annexin. (339 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PIK3C2BPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1; Belongs to the PI3/PI4-kinase family. (1634 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
GSDMDgasdermin-D. (486 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1195 aa)
ACBD3Golgi resident protein GCP60 isoform X1. (408 aa)
MYO6Unconventional myosin-VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1295 aa)
KLC3Kinesin light chain 3. (505 aa)
CYTH2Cytohesin-2 isoform X1. (421 aa)
BAXApoptosis regulator BAX. (192 aa)
IRAK4Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa)
RHOATransforming protein RhoA. (193 aa)
FYCO1FYVE and coiled-coil domain-containing protein 1 isoform X1. (1477 aa)
DNM2Dynamin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (708 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X2. (435 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (303 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1042 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (404 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (343 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (210 aa)
RELATranscription factor p65 isoform X1. (520 aa)
KLC2Kinesin light chain 2 isoform X1. (622 aa)
HRASGTPase HRas isoform X1. (196 aa)
LOC103017407Tumor necrosis factor receptor superfamily member 26-like. (327 aa)
LOC103003361Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TLR5Toll-like receptor 5; Belongs to the Toll-like receptor family. (858 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (175 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (974 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (515 aa)
CASP7Caspase-7; Belongs to the peptidase C14A family. (301 aa)
FBXO22F-box only protein 22 isoform X1. (406 aa)
VPS39vam6/Vps39-like protein. (875 aa)
RHOGRho-related GTP-binding protein RhoG. (191 aa)
LOC10301827040S ribosomal protein S3. (194 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (929 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
AHNAKLOW QUALITY PROTEIN: neuroblast differentiation-associated protein AHNAK. (5665 aa)
LOC103010163Toll-like receptor 9 isoform X1. (1323 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (716 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (338 aa)
TCF7L1Transcription factor 7-like 1 isoform X1. (439 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
NAIPBaculoviral IAP repeat-containing protein 1 isoform X1. (1402 aa)
ARL17AADP-ribosylation factor-like 17-like; Belongs to the small GTPase superfamily. Arf family. (181 aa)
KLC1Kinesin light chain 1 isoform X1. (652 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa)
DYNLL2Dynein light chain. (89 aa)
EXOC4Exocyst complex component 4. (975 aa)
FLNCfilamin-C. (2693 aa)
WASLNeural Wiskott-Aldrich syndrome protein isoform X1. (511 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (558 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
LOC103013898Ras-related protein Rab-5C. (216 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (275 aa)
S100A10Protein S100-A10; Belongs to the S-100 family. (97 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (841 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
TLR6Toll-like receptor 6; Belongs to the Toll-like receptor family. (797 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (733 aa)
DYNC1H1Cytoplasmic dynein 1 heavy chain 1. (4622 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
RAB5BRas-related protein Rab-5B. (215 aa)
NCKAP1LNck-associated protein 1-like. (1134 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PLEKHM1Pleckstrin homology domain-containing family M member 1 isoform X1. (1062 aa)
VPS18Vacuolar protein sorting-associated protein 18 homolog. (973 aa)
RIPK3LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 3. (564 aa)
NFKBIANF-kappa-B inhibitor alpha. (280 aa)
PIK3CGLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1101 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa)
MYL5Myosin light chain 5 isoform X1. (215 aa)
RAB9ARas-related protein Rab-9A. (201 aa)
PKN1Serine/threonine-protein kinase N1. (796 aa)
STX10Syntaxin-10 isoform X1. (249 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (536 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
DYNLRB2Dynein light chain roadblock-type 2. (137 aa)
LOC103013736Uncharacterized protein LOC103013736. (365 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
DYNC1I2Cytoplasmic dynein 1 intermediate chain 2 isoform X1. (632 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein. (226 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
RHOBRho-related GTP-binding protein RhoB. (196 aa)
LOC103019676Rho-related GTP-binding protein RhoG-like. (191 aa)
RILPRab-interacting lysosomal protein isoform X1. (392 aa)
IL6Interleukin-6. (208 aa)
DYNLL1Dynein light chain. (89 aa)
DYNLT3Dynein light chain Tctex-type 3. (116 aa)
FOSProto-oncogene c-Fos. (380 aa)
LY96Lymphocyte antigen 96. (160 aa)
RAB9BRas-related protein Rab-9B. (201 aa)
ELMO2Engulfment and cell motility protein 2 isoform X1. (732 aa)
CSE1LExportin-2. (971 aa)
IRAK1Interleukin-1 receptor-associated kinase 1. (340 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (368 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (707 aa)
CYTH1Cytohesin-1 isoform X1. (399 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
DYNLT1Dynein light chain Tctex-type 1 isoform X1. (113 aa)
MYLPFMyosin regulatory light chain 2, skeletal muscle isoform. (170 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
LOC103004444Apoptosis-associated speck-like protein containing a CARD. (195 aa)
MYL10Myosin regulatory light chain 10. (167 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (194 aa)
ACTBActin, cytoplasmic 1. (375 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (387 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
CYTH3Cytohesin-3. (403 aa)
KPNA4Importin subunit alpha; Functions in nuclear protein import. (502 aa)
GCC2GRIP and coiled-coil domain-containing protein 2 isoform X1. (1680 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (855 aa)
RALARas-related protein Ral-A. (206 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (288 aa)
PFN2Profilin; Belongs to the profilin family. (91 aa)
RAB7BRas-related protein Rab-7b isoform X1. (205 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (506 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
VPS33AVacuolar protein sorting-associated protein 33A isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
TLR2Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
DYNC2LI1Cytoplasmic dynein 2 light intermediate chain 1 isoform X1. (351 aa)
NCKAP1Nck-associated protein 1 isoform X2. (1102 aa)
LOC103017780Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (486 aa)
LOC102999215Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (620 aa)
DYNC2H1Cytoplasmic dynein 2 heavy chain 1. (4307 aa)
LOC103012084Caspase-13 isoform X1; Belongs to the peptidase C14A family. (377 aa)
NLRC4NLR family CARD domain-containing protein 4. (989 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (604 aa)
CASP1Caspase-1; Belongs to the peptidase C14A family. (404 aa)
LOC103010734Myosin regulatory light chain 12B. (171 aa)
LOC103010250Myosin regulatory light polypeptide 9 isoform X1. (178 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
FLNBfilamin-B isoform X1. (2633 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
BRK1Protein BRICK1. (75 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
RHOJRho-related GTP-binding protein RhoJ. (236 aa)
MYL9Myosin regulatory light polypeptide 9. (172 aa)
EXOC5Exocyst complex component 5 isoform X1. (708 aa)
DYNLRB1Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. (96 aa)
CTNNB1Catenin beta-1. (767 aa)
KPNA3Importin subunit alpha; Functions in nuclear protein import. (512 aa)
HSP90AB1Heat shock protein HSP 90-beta. (724 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TRAF2TNF receptor-associated factor. (412 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa)
LOC102999798Mitogen-activated protein kinase. (203 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
PIK3C2GPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family. (1454 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (742 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (873 aa)
DYNC1I1Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (628 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
M6PRCation-dependent mannose-6-phosphate receptor. (278 aa)
MAPK1Mitogen-activated protein kinase 1. (263 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (288 aa)
SNX33Sorting nexin. (574 aa)
LOC103007269Dynein light chain. (89 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
KLC4Kinesin light chain 4 isoform X1. (622 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (422 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (343 aa)
AHNAK2LOW QUALITY PROTEIN: protein AHNAK2. (3151 aa)
LOC103007471Ras-related protein Rab-7b-like isoform X1. (145 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SNX18Sorting nexin-18. (495 aa)
MAPK13Mitogen-activated protein kinase. (288 aa)
FHOD1FH1/FH2 domain-containing protein 1. (1147 aa)
FA2HLOW QUALITY PROTEIN: fatty acid 2-hydroxylase; Belongs to the sterol desaturase family. (722 aa)
ARF1ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
NLRP3NACHT, LRR and PYD domains-containing protein 3 isoform X1. (1056 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (818 aa)
PIK3C2APhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1; Belongs to the PI3/PI4-kinase family. (1689 aa)
LOC103003848Pleckstrin homology domain-containing family M member 2. (842 aa)
FLNAfilamin-A. (2305 aa)
SNX9Sorting nexin. (624 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (539 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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