STRINGSTRING
purU purU folDch folDch Arad_1180 Arad_1180 Arad_1182 Arad_1182 glyA glyA Arad_2506 Arad_2506 gcvT gcvT gcvH gcvH gcvP gcvP metH metH Arad_2814 Arad_2814 Arad_2816 Arad_2816 Arad_2818 Arad_2818 metH-2 metH-2 Arad_2823 Arad_2823 Arad_2824 Arad_2824 Arad_2827 Arad_2827 Arad_2828 Arad_2828 Arad_2829 Arad_2829 Arad_2831 Arad_2831 metF metF metH-3 metH-3 tdh tdh kbl kbl fhs fhs Arad_3336 Arad_3336 Arad_3491 Arad_3491 soxAe soxAe soxDe soxDe soxBe soxBe Arad_3838 Arad_3838 soxGch soxGch soxAch soxAch soxDch soxDch soxBch soxBch hemAch hemAch Arad_4728 Arad_4728 Arad_7067 Arad_7067 Arad_7728 Arad_7728 soxGe soxGe soxAe-2 soxAe-2 soxDe-2 soxDe-2 soxBe-2 soxBe-2 glxA glxA Arad_8360 Arad_8360 glxB glxB glxC glxC glxD glxD glnT glnT purU-2 purU-2 folDch-2 folDch-2 Arad_8372 Arad_8372 Arad_8373 Arad_8373 Arad_8374 Arad_8374 Arad_8376 Arad_8376 Arad_8377 Arad_8377 gcvT-2 gcvT-2 purU-3 purU-3 folDch-3 folDch-3 Arad_9001 Arad_9001 Arad_9002 Arad_9002 Arad_9004 Arad_9004
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa)
folDchMethylenetetrahydrofolate dehydrogenase/cyclohydrolase protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (299 aa)
Arad_1180Ring hydroxylating dioxygenase alpha-subunit. (395 aa)
Arad_1182Ferredoxin oxidoreductase protein. (362 aa)
glyASerine hydroxymethyltransferase 1 protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (432 aa)
Arad_2506Transcription regulator protein. (140 aa)
gcvTGlycine cleavage system T protein. (356 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (120 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (954 aa)
metH5-methyltetrahydrofolate--homocysteine S-methyltransferase protein. (337 aa)
Arad_2814Conserved hypothetical protein. (246 aa)
Arad_2816Conserved hypothetical protein. (229 aa)
Arad_2818Trimethylamine methyltransferase protein; Belongs to the trimethylamine methyltransferase family. (526 aa)
metH-25-methyltetrahydrofolate--homocysteine S-methyltransferase protein. (233 aa)
Arad_2823Conserved hypothetical protein. (243 aa)
Arad_2824Conserved hypothetical protein. (100 aa)
Arad_2827Hypothetical protein. (192 aa)
Arad_2828Oxidoreductase protein; Belongs to the methylenetetrahydrofolate reductase family. (368 aa)
Arad_2829Methyltransferase protein. (321 aa)
Arad_2831Conserved hypothetical protein. (117 aa)
metF5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (304 aa)
metH-35-methyltetrahydrofolate--homocysteine S-methyltransferase protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1292 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (345 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (395 aa)
fhsFormate-tetrahydrofolate ligase protein; Belongs to the formate--tetrahydrofolate ligase family. (559 aa)
Arad_3336Conserved hypothetical protein; Belongs to the trimethylamine methyltransferase family. (528 aa)
Arad_3491Glycine cleavage system T protein; Belongs to the GcvT family. (808 aa)
soxAeSarcosine oxidase alpha subunit protein. (985 aa)
soxDeSarcosine oxidase delta subunit protein. (91 aa)
soxBeSarcosine oxidase beta subunit protein. (417 aa)
Arad_3838Threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (348 aa)
soxGchSarcosine oxidase gamma subunit protein. (182 aa)
soxAchSarcosine oxidase alpha subunit protein. (997 aa)
soxDchSarcosine oxidase delta subunit protein. (121 aa)
soxBchSarcosine oxidase beta subunit protein. (417 aa)
hemAch8-amino-7-oxononanoate synthase protein. (409 aa)
Arad_4728Transcriptional regulator protein. (227 aa)
Arad_7067Glycine cleavage system T protein; Belongs to the GcvT family. (813 aa)
Arad_7728Sarcosine dehydrogenase protein; Belongs to the GcvT family. (853 aa)
soxGeSarcosine oxidase gamma subunit protein. (184 aa)
soxAe-2Sarcosine oxidase alpha subunit protein. (977 aa)
soxDe-2Sarcosine oxidase delta subunit protein. (92 aa)
soxBe-2Sarcosine oxidase beta subunit protein. (416 aa)
glxATranscriptional regulator protein. (319 aa)
Arad_8360Transcriptional regulator protein. (227 aa)
glxBAmidophosphoribosyl transferase protein. (302 aa)
glxCFormyl-methanofuran dehydrogenase domain 3 protein. (228 aa)
glxDGlutamate synthase large subunit 2 protein; Belongs to the glutamate synthase family. (442 aa)
glnTGlutamine synthetase III protein. (435 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa)
folDch-2Methylenetetrahydrofolate dehydrogenase/cyclohydrolase protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (304 aa)
Arad_8372Aminomethyltransferase protein; Belongs to the GcvT family. (377 aa)
Arad_8373Conserved hypothetical protein. (201 aa)
Arad_8374Ferredoxin protein. (321 aa)
Arad_8376Conserved hypothetical protein. (346 aa)
Arad_8377Monooxygenase protein. (445 aa)
gcvT-2Glycine cleavage system T protein; Belongs to the GcvT family. (789 aa)
purU-3Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa)
folDch-3Methylenetetrahydrofolate dehydrogenase/cyclohydrolase protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (304 aa)
Arad_9001Transcriptional regulator protein. (209 aa)
Arad_9002Flavoprotein oxidoreductase. (678 aa)
Arad_9004Transcriptional regulator protein. (200 aa)
Your Current Organism:
Agrobacterium radiobacter
NCBI taxonomy Id: 311403
Other names: A. radiobacter K84, Agrobacterium radiobacter K84, Agrobacterium radiobacter str. K84, Agrobacterium radiobacter strain K84, Agrobacterium rhizogenes K84, Agrobacterium tumefaciens K84, Rhizobium radiobacter K84
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