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Arad_0248 Arad_0248 atpC atpC pyk pyk fbaB fbaB pgk pgk tkt tkt bkdA2 bkdA2 Arad_3385 Arad_3385 Arad_3331 Arad_3331 pfk pfk mazG mazG eno eno Arad_9475 Arad_9475 Arad_8983 Arad_8983 hrcN hrcN Arad_8606 Arad_8606 atpG atpG atpD atpD atpB atpB fliI fliI Arad_0763 Arad_0763 sucA sucA pgi pgi atpH atpH atpA atpA rdgB rdgB glk glk Arad_8187 Arad_8187 gpmA gpmA Arad_0276 Arad_0276 atpE atpE atpF1 atpF1 atpF atpF gpmB gpmB ndk ndk dgt dgt
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Arad_0248Phosphoglycerate mutase protein. (188 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (479 aa)
fbaBFructose-bisphosphate aldolase protein. (340 aa)
pgkPhosphoglycerate kinase protein; Belongs to the phosphoglycerate kinase family. (415 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (660 aa)
bkdA22-oxoisovalerate dehydrogenase beta subunit protein. (1107 aa)
Arad_3385Phosphoglycerate mutase protein. (193 aa)
Arad_3331Conserved hypothetical protein. (235 aa)
pfk6-phosphofructokinase protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (403 aa)
mazGMazG protein. (278 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa)
Arad_9475Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. (248 aa)
Arad_8983Aldolase. (266 aa)
hrcNType III secretion system ATP synthase protein. (439 aa)
Arad_8606Aldolase protein. (280 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (485 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (250 aa)
fliIH(+)-transporting ATP synthase. (462 aa)
Arad_0763Conserved hypothetical protein. (293 aa)
sucA2-oxoglutarate dehydrogenase, E1 component. (994 aa)
pgiGlucose-6-phosphate isomerase protein; Belongs to the GPI family. (541 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (194 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (510 aa)
rdgBNon-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (214 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (340 aa)
Arad_8187Aldolase protein. (274 aa)
gpmAPhosphoglycerate mutase protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (211 aa)
Arad_0276Conserved hypothetical protein. (230 aa)
atpEATP synthase protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa)
atpF1ATP synthase protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (197 aa)
atpFATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (163 aa)
gpmBPhosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. (198 aa)
ndkNucleoside-diphosphate-kinase protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
dgtDeoxyguanosinetriphosphate triphosphohydrolase protein; Belongs to the dGTPase family. Type 2 subfamily. (405 aa)
Your Current Organism:
Agrobacterium radiobacter
NCBI taxonomy Id: 311403
Other names: A. radiobacter K84, Agrobacterium radiobacter K84, Agrobacterium radiobacter str. K84, Agrobacterium radiobacter strain K84, Agrobacterium rhizogenes K84, Agrobacterium tumefaciens K84, Rhizobium radiobacter K84
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