(108 nodes) Intracellular signal transduction network (Agrobacterium radiobacter)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cyaA	Adenylate cyclase protein. (445 aa)
	Arad_9735	Two-component sensor histidine kinase/response regulator hybrid protein. (593 aa)
	Arad_9694	Two-component response regulator protein. (240 aa)
	Arad_9693	Two-component sensor histidine kinase protein. (460 aa)
	cyaCe	Adenylate cyclase protein. (574 aa)
	kdpE	Two-component response regulator protein (probably regulates osmosensitive potassium channel). (230 aa)
	kdpD	Two-component sensor histidine kinase protein (probably regulates osmosensitive potassium channel). (903 aa)
	Arad_9445	Two-component response regulator protein. (158 aa)
	feuP-3	Two-component response regulator protein. (220 aa)
	feuQ-2	Two-component sensor histidine kinase protein. (465 aa)
	Arad_9284	Two-component sensor histidine kinase protein. (467 aa)
	Arad_9283	Two-component response regulator protein. (240 aa)
	dctD-3	Two-component response regulator protein regulating C4-dicarboxylate transport system. (312 aa)
	dctB-2	Two-component sensor histidine kinase protein regulating C4-dicarboxylate transport system. (532 aa)
	Arad_9128	Two-component response regulator protein. (243 aa)
	Arad_9127	Two-component sensor histidine kinase protein. (425 aa)
	Arad_9104	Two-component sensor histidine kinase protein. (474 aa)
	dctD-2	Two-component response regulator protein regulating C4-dicarboxylate transport system. (436 aa)
	dctB	Two-component sensor histidine kinase protein regulating C4-dicarboxylate transport system. (506 aa)
	nasT	Two-component response regulator protein. (195 aa)
	Arad_8583	Two-component sensor histidine kinase protein. (440 aa)
	Arad_8582	Two-component response regulator protein. (241 aa)
	Arad_8426	Two-component sensor histidine kinase protein. (487 aa)
	Arad_8258	Serine/threonine kinase protein of two-component system. (354 aa)
	nodW-2	Two-component nodulation response regulator protein. (204 aa)
	cyaD	Adenylate cyclase protein. (723 aa)
	Arad_7924	Two-component sensor histidine kinase/response regulator hybrid protein. (674 aa)
	Arad_7923	Two-component response regulator protein. (464 aa)
	Arad_7812	Conserved hypothetical protein. (586 aa)
	dctD	Two-component response regulator protein regulating C4-dicarboxylate transport system. (450 aa)
	Arad_7649	Two-component sensor histidine kinase protein; Member of the two-component regulatory system DctB/DctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals. (640 aa)
	virB11d	Transport secretion system IV. (367 aa)
	Arad_7575	Two-component response regulator protein. (241 aa)
	Arad_7390	Two-component sensor histidine kinase protein. (498 aa)
	Arad_7389	Two-component response regulator protein. (241 aa)
	Arad_7332	Two-component response regulator protein. (122 aa)
	Arad_7290	Adenylate cyclase protein. (399 aa)
	Arad_7182	Serine/threonine kinase protein of two-component system. (514 aa)
	Arad_7181	Two-component response regulator protein. (213 aa)
	Arad_7180	Two-component response regulator protein. (133 aa)
	Arad_7021	Two-component sensor histidine kinase protein. (463 aa)
	Arad_7020	Two-component response regulator protein. (224 aa)
	Arad_4537	Conserved hypothetical protein. (649 aa)
	Arad_4526	Two-component sensor histidine kinase protein. (452 aa)
	Arad_4525	Two-component response regulator protein. (222 aa)
	feuP-2	Two-component response regulator protein. (218 aa)
	Arad_4499	Two-component sensor histidine kinase protein. (459 aa)
	Arad_4476	Two-component sensor histidine kinase protein. (429 aa)
	Arad_4475	Two-component response regulator protein. (228 aa)
	Arad_4444	Two-component response regulator protein. (227 aa)
	Arad_4203	Two-component response regulator protein. (119 aa)
	Arad_4023	Two-component sensor histidine kinase protein. (446 aa)
	Arad_4022	Two-component response regulator protein. (219 aa)
	Arad_3856	Two-component response regulator protein. (121 aa)
	tacA	Sigma-54-dependent transcriptional regulator (activator) protein. (502 aa)
	cyaG1	Adenylate cyclase protein. (403 aa)
	Arad_3506	Conserved hypothetical protein. (215 aa)
	Arad_3504	Two-component response regulator protein. (120 aa)
	ctrA	Two-component response regulator protein controls chromosomal replication initiation. (233 aa)
	tcrX	Two-component response regulator protein. (264 aa)
	Arad_3380	Two-component response regulator protein. (136 aa)
	Arad_3179	Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (306 aa)
	Arad_3170	Two-component sensor histidine kinase protein. (459 aa)
	Arad_3169	Two-component response regulator protein. (233 aa)
	Arad_3134	Conserved hypothetical protein. (263 aa)
	rrpX	Two-component response regulator protein. (276 aa)
	Arad_2839	Two-component response regulator protein. (415 aa)
	Arad_2756	Adenylate cyclase protein. (352 aa)
	Arad_2731	Two-component sensor histidine kinase protein. (509 aa)
	Arad_2642	Conserved hypothetical protein. (122 aa)
	Arad_2623	Two-component sensor histidine kinase/response regulator hybrid protein. (871 aa)
	cyaJ	Adenylate cyclase protein. (306 aa)
	Arad_2450	Adenylate cyclase protein. (611 aa)
	ntrX	Nitrogen regulation (two-component response regulator) protein. (454 aa)
	ntrY	Nitrogen regulation (two-component sensor histidine kinase) protein. (757 aa)
	ntrC	Nitrogen regulation protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (483 aa)
	ntrB	Nitrogen regulation (two-component sensor histidine kinase) protein. (385 aa)
	celR2	Two-component response regulator protein. (458 aa)
	celR1	Two-component response regulator protein. (133 aa)
	Arad_1700	Conserved hypothetical protein. (168 aa)
	exsF	Two-component response regulator protein. (169 aa)
	Arad_1503	Two-component sensor histidine kinase protein. (771 aa)
	ragB	Two-component sensor histidine kinase protein. (471 aa)
	ragA	Two-component response regulator protein. (252 aa)
	feuQ	Two-component sensor histidine kinase protein. (464 aa)
	feuP	Two-component response regulator protein. (223 aa)
	Arad_1489	Conserved hypothetical protein. (82 aa)
	Arad_1478	Two-component sensor histidine kinase protein. (510 aa)
	Arad_1096	Two-component sensor histidine kinase protein. (568 aa)
	mctS	Two-component sensor histidine kinase protein. (414 aa)
	phoB-2	Phosphate regulon transcriptional regulatory protein PhoB. (226 aa)
	cyaG2	Adenylate cyclase protein. (412 aa)
	Arad_0966	Two-component sensor histidine kinase protein. (1190 aa)
	Arad_0907	Two-component response regulator protein. (223 aa)
	cheY2	Chemotaxis two-component response regulator protein. (129 aa)
	cheBch1	Protein-glutamate methylesterase protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (347 aa)
	cheY1	Chemotaxis two-component response regulator protein. (121 aa)
	phoB	Phosphate regulon transcriptional regulatory protein PhoB. (211 aa)
	phoR	Phosphate regulon sensor kinase PhoR. (420 aa)
	cyaH	Adenylate/guanylate cyclase protein. (469 aa)
	Arad_0229	Two-component sensor histidine kinase protein. (451 aa)
	Arad_0228	Two-component response regulator protein. (239 aa)
	actS	Two-component sensor histidine kinase protein. (445 aa)
	actR	Two-component response regulator protein. (195 aa)
	chvI	Two-component response regulator protein. (249 aa)
	chvG	Two-component sensor histidine kinase protein. (614 aa)
	Arad_0044	Conserved hypothetical protein. (150 aa)
	Arad_0038	Two-component sensor histidine kinase protein. (824 aa)

Your Current Organism:

Agrobacterium radiobacter

NCBI taxonomy Id: 311403
Other names: A. radiobacter K84, Agrobacterium radiobacter K84, Agrobacterium radiobacter str. K84, Agrobacterium radiobacter strain K84, Agrobacterium rhizogenes K84, Agrobacterium tumefaciens K84, Rhizobium radiobacter K84

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arad_0038	Arad_0044	Arad_0038	Arad_0044	Two-component sensor histidine kinase protein.	Conserved hypothetical protein.	0.497
Arad_0038	Arad_0228	Arad_0038	Arad_0228	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.704
Arad_0038	Arad_0907	Arad_0038	Arad_0907	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.713
Arad_0038	Arad_0966	Arad_0038	Arad_0966	Two-component sensor histidine kinase protein.	Two-component sensor histidine kinase protein.	0.541
Arad_0038	Arad_1096	Arad_0038	Arad_1096	Two-component sensor histidine kinase protein.	Two-component sensor histidine kinase protein.	0.714
Arad_0038	Arad_1478	Arad_0038	Arad_1478	Two-component sensor histidine kinase protein.	Two-component sensor histidine kinase protein.	0.434
Arad_0038	Arad_1489	Arad_0038	Arad_1489	Two-component sensor histidine kinase protein.	Conserved hypothetical protein.	0.620
Arad_0038	Arad_1503	Arad_0038	Arad_1503	Two-component sensor histidine kinase protein.	Two-component sensor histidine kinase protein.	0.567
Arad_0038	Arad_2623	Arad_0038	Arad_2623	Two-component sensor histidine kinase protein.	Two-component sensor histidine kinase/response regulator hybrid protein.	0.719
Arad_0038	Arad_2731	Arad_0038	Arad_2731	Two-component sensor histidine kinase protein.	Two-component sensor histidine kinase protein.	0.438
Arad_0038	Arad_3169	Arad_0038	Arad_3169	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.810
Arad_0038	Arad_3170	Arad_0038	Arad_3170	Two-component sensor histidine kinase protein.	Two-component sensor histidine kinase protein.	0.598
Arad_0038	Arad_3380	Arad_0038	Arad_3380	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.732
Arad_0038	Arad_3504	Arad_0038	Arad_3504	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.552
Arad_0038	Arad_3506	Arad_0038	Arad_3506	Two-component sensor histidine kinase protein.	Conserved hypothetical protein.	0.710
Arad_0038	Arad_3856	Arad_0038	Arad_3856	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.710
Arad_0038	Arad_4022	Arad_0038	Arad_4022	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.712
Arad_0038	Arad_4203	Arad_0038	Arad_4203	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.588
Arad_0038	Arad_4444	Arad_0038	Arad_4444	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.782
Arad_0038	Arad_4475	Arad_0038	Arad_4475	Two-component sensor histidine kinase protein.	Two-component response regulator protein.	0.733

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