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| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (205 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (303 aa) |
| | coaA | Pantothenate kinase. (331 aa) |
| | cmk | Cytidylate kinase. (214 aa) |
| | moeB | Molybdopterin biosynthesis protein. (256 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (329 aa) |
| | Arad_0224 | Purine/pyrimidine phosphoribosyltransferase protein. (226 aa) |
| | phnN | Phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (180 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (434 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (406 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa) |
| | guaA1 | GMP synthase - glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. (520 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (230 aa) |
| | dut | Deoxyuridine 5'triphosphate nucleotidohydrolase protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (156 aa) |
| | coaBC | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa) |
| | Arad_0591 | Allantoinase protein. (467 aa) |
| | cyaH | Adenylate/guanylate cyclase protein. (469 aa) |
| | pyrC | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (346 aa) |
| | pyrE | Orotate phosphoribosyltransferase protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (232 aa) |
| | Arad_0763 | Conserved hypothetical protein. (293 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (362 aa) |
| | fliI | H(+)-transporting ATP synthase. (462 aa) |
| | folDch | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (299 aa) |
| | Arad_0962 | acetoacetyl-CoA synthase. (650 aa) |
| | cyaG2 | Adenylate cyclase protein. (412 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (327 aa) |
| | Arad_1088 | Inositol monophosphatase protein. (269 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (355 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (250 aa) |
| | atpE | ATP synthase protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa) |
| | atpF1 | ATP synthase protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (197 aa) |
| | atpF | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (163 aa) |
| | moaB | Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (184 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (304 aa) |
| | purD | Phosphoribosylamine-glycine ligase protein; Belongs to the GARS family. (423 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (206 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (335 aa) |
| | Arad_1256 | Transcriptional regulator protein; Belongs to the UPF0301 (AlgH) family. (201 aa) |
| | Arad_1526 | Diacylglycerol kinase protein. (315 aa) |
| | amn | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (500 aa) |
| | Arad_1608 | Hydrolase protein. (205 aa) |
| | pssA | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (286 aa) |
| | psd | Phosphatidylserine decarboxylase proenzyme protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (232 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (494 aa) |
| | gmk2 | Guanylate kinase (GMP kinase) protein; Essential for recycling GMP and indirectly, cGMP. (220 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (341 aa) |
| | Arad_1689 | Conserved hypothetical protein. (182 aa) |
| | ndk | Nucleoside-diphosphate-kinase protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | moaE | Molybdopterin converting factor subunit 2 protein. (155 aa) |
| | moaD | Molybdopterin converting factor, subunit 1. (85 aa) |
| | pgsA | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (195 aa) |
| | Arad_1721 | Anaerobic dehydrogenase protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (707 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (225 aa) |
| | purM | 5'-phosphoribosyl-5-aminoimidazole synthetase protein. (357 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (348 aa) |
| | plsY | Conserved hypothetical membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (206 aa) |
| | Arad_1896 | Dihydroorotase protein. (429 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (318 aa) |
| | Arad_1925 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) |
| | nadK | NAD(+) kinase protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (257 aa) |
| | Arad_1950 | Conserved hypothetical protein. (168 aa) |
| | adk | Adenylate kinase (ATP-AMP transphosphorylase) protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa) |
| | gpt | Xanthine-guanine phosphoribosyltransferase protein; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (165 aa) |
| | cinA1 | Competence-damage associated protein. (257 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa) |
| | cdsAch | Phosphatidate cytidylyltransferase protein; Belongs to the CDS family. (278 aa) |
| | lpxD | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (355 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (157 aa) |
| | lpxA | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (271 aa) |
| | Arad_2233 | Conserved hypothetical protein. (293 aa) |
| | lpxB | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (393 aa) |
| | pdhA2 | Pyruvate dehydrogenase beta subunit protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (458 aa) |
| | Arad_2256 | DNA topology modulation kinase FlaR-like protein. (199 aa) |
| | Arad_2258 | DNA topology modulation kinase FlaR-like protein. (188 aa) |
| | cinA2 | Competence-damage associated protein; Belongs to the CinA family. (166 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (406 aa) |
| | pcs | Phosphatidylcholine synthase protein; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (241 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (453 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (227 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (164 aa) |
| | moeA | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (408 aa) |
| | Arad_2450 | Adenylate cyclase protein. (611 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (566 aa) |
| | folE | GTP cyclohydrolase I. (207 aa) |
| | selA | L-seryl-tRNA(ser) selenium transferase protein. (544 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (433 aa) |
| | purC-2 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (254 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (743 aa) |
| | cyaJ | Adenylate cyclase protein. (306 aa) |
| | Arad_2671 | Metallo-phosphoesterase protein. (274 aa) |
| | nadE | NAD(+) synthase (glutamine-hydrolysing) protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (559 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (355 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (216 aa) |
| | mobB | Molybdopterin-guanine dinucleotide biosynthesis protein B. (176 aa) |
| | dgkA | Diacylglycerol kinase protein; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (130 aa) |
| | Arad_2756 | Adenylate cyclase protein. (352 aa) |
| | Arad_2778 | Hydroxymyristoyl-(acyl carrier) dehydratase transmembrane protein. (157 aa) |
| | acpP | Acyl carrier protein. (94 aa) |
| | thyA | Thymidylate synthase protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (307 aa) |
| | pncA | Pyrazinamidase/nicotinamidase protein. (207 aa) |
| | lpxC | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (318 aa) |
| | Arad_3055 | Lactoylglutathione lyase protein. (116 aa) |
| | carA | Carbamoyl-phosphate synthase small chain (glutamine-hydrolysing) protein; Belongs to the CarA family. (402 aa) |
| | carB | Carbamoyl-phosphate synthase large chain (ammonia chain) protein; Belongs to the CarB family. (1161 aa) |
| | prsAch | Ribose-phosphate pyrophosphokinase protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (180 aa) |
| | tdk | Thymidine kinase protein. (193 aa) |
| | bkdA2 | 2-oxoisovalerate dehydrogenase beta subunit protein. (1107 aa) |
| | Arad_3441 | Dihydroorotate oxidase protein. (437 aa) |
| | hydA | Dihydropyrimidinase. (484 aa) |
| | pssB | Exopolysaccharide production protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (264 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa) |
| | Arad_3549 | Choline kinase protein. (301 aa) |
| | cyaG1 | Adenylate cyclase protein. (403 aa) |
| | pgsAb | CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase protein. (216 aa) |
| | Arad_3663 | Acyltransferase protein. (217 aa) |
| | Arad_3694 | Phosphohydrolase protein. (306 aa) |
| | thiEch | Thiamine-phosphate pyrophosphorylase protein. (217 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (352 aa) |
| | purN-2 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (199 aa) |
| | Arad_4009 | L-ribulokinase protein. (528 aa) |
| | Arad_4097 | Conserved hypothetical protein. (689 aa) |
| | Arad_4164 | acetyl-CoA synthetase protein. (548 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa) |
| | plsC | 1-acyl-sn-glycerol-3-phosphate acyltransferase protein. (266 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | Arad_4259 | DNA topology modulation kinase FlaR-like protein. (170 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (397 aa) |
| | fdhD | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (275 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (485 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (510 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (194 aa) |
| | frcK-2 | Pantothenate kinase protein. (242 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)+) protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (329 aa) |
| | Arad_4659 | Thiamine pyrophosphokinase. (217 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (417 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (193 aa) |
| | Arad_4910 | Phosphatase protein. (247 aa) |
| | Arad_4923 | Pyridoxal kinase; Belongs to the pyridoxine kinase family. (290 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH. (538 aa) |
| | acsA | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa) |
| | Arad_7004 | Conserved Hypothetical Protein. (215 aa) |
| | Arad_7095 | CTP synthase protein. (408 aa) |
| | matB | long-chain-fatty-acid-CoA ligase protein. (910 aa) |
| | Arad_7203 | Gentisate 1,2-dioxygenase. (355 aa) |
| | Arad_7290 | Adenylate cyclase protein. (399 aa) |
| | thiEb | Thiamine-phosphate pyrophosphorylase protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (204 aa) |
| | thiG | Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (257 aa) |
| | thiS | Sulfur transfer protein. (65 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (608 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa) |
| | nadE-2 | NAD(+) synthase (glutamine-hydrolysing) protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (332 aa) |
| | Arad_7868 | Pyruvate Decarboxylase. (400 aa) |
| | Arad_7907 | Formate dehydrogenase alpha chain protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (755 aa) |
| | moeA-2 | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (405 aa) |
| | Arad_8020 | Adenine phosphoribosyltransferase. (210 aa) |
| | Arad_8026 | Phosphoribosyltransferase. (237 aa) |
| | Arad_8072 | AIR synthase protein. (325 aa) |
| | cyaD | Adenylate cyclase protein. (723 aa) |
| | Arad_8248 | Conserved hypothetical protein. (241 aa) |
| | nrdF | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (329 aa) |
| | purU-2 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa) |
| | folDch-2 | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (304 aa) |
| | Arad_8493 | Conserved hypothetical protein. (140 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (415 aa) |
| | Arad_8682 | Conserved hypothetical protein. (565 aa) |
| | purU-3 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa) |
| | folDch-3 | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (304 aa) |
| | hrcN | Type III secretion system ATP synthase protein. (439 aa) |
| | pdxA-2 | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (332 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (323 aa) |
| | nadB | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (513 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (285 aa) |
| | Arad_8947 | Formate dehydrogenase alpha chain protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (756 aa) |
| | thiM | Hydoxyethylthiazole kinase protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (268 aa) |
| | thiEe | Thiamine-phosphate pyrophosphorylase protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (211 aa) |
| | thiD | Phosphomethylpyrimidine kinase protein. (273 aa) |
| | cls | Cardiolipin synthethase transmembrane protein. (487 aa) |
| | cyaCe | Adenylate cyclase protein. (574 aa) |
| | cyaA | Adenylate cyclase protein. (445 aa) |
| | hydA-2 | Dihydropyrimidinase. (482 aa) |
| | rtlK | L-ribulokinase protein. (547 aa) |
| | Arad_9809 | Choline kinase. (311 aa) |
| | Arad_9811 | Aminoglycoside phosphotransferase. (321 aa) |
| | udp | Uridine phosphorylase. (277 aa) |
