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| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (329 aa) |
| | ade | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (625 aa) |
| | ade-2 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (594 aa) |
| | Arad_0265 | Inosine-uridine preferring nucleoside hydrolase protein. (307 aa) |
| | Arad_0344 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (266 aa) |
| | add | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (322 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (406 aa) |
| | Arad_0423 | Glutamine amidotransferase protein. (236 aa) |
| | guaA1 | GMP synthase - glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. (520 aa) |
| | Arad_0591 | Allantoinase protein. (467 aa) |
| | rdgB | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (214 aa) |
| | iunH1 | Inosine-uridine preferring nucleoside hydrolase protein. (314 aa) |
| | ppx1 | Exopolyphosphatase protein. (556 aa) |
| | cyaG2 | Adenylate cyclase protein. (412 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa) |
| | purD | Phosphoribosylamine-glycine ligase protein; Belongs to the GARS family. (423 aa) |
| | cysN | Sulfate adenylate transferase subunit 1 protein (cysteine biosynthesis protein); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (494 aa) |
| | cysD | Sulfate adenylyltransferase subunit 2 protein (cysteine biosynthesis protein). (317 aa) |
| | amn | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (500 aa) |
| | relA | Guanosine-3; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (754 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (494 aa) |
| | gmk2 | Guanylate kinase (GMP kinase) protein; Essential for recycling GMP and indirectly, cGMP. (220 aa) |
| | ndk | Nucleoside-diphosphate-kinase protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (225 aa) |
| | purM | 5'-phosphoribosyl-5-aminoimidazole synthetase protein. (357 aa) |
| | ppx2 | Exopolyphosphatase protein. (506 aa) |
| | cyaB | Adenylate cyclase protein. (350 aa) |
| | adk | Adenylate kinase (ATP-AMP transphosphorylase) protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa) |
| | Arad_2051 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1264 aa) |
| | gpt | Xanthine-guanine phosphoribosyltransferase protein; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (165 aa) |
| | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family. (662 aa) |
| | dgt | Deoxyguanosinetriphosphate triphosphohydrolase protein; Belongs to the dGTPase family. Type 2 subfamily. (405 aa) |
| | surE | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (257 aa) |
| | mazG | MazG protein. (278 aa) |
| | Arad_2450 | Adenylate cyclase protein. (611 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (433 aa) |
| | purC-2 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (254 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (743 aa) |
| | cyaJ | Adenylate cyclase protein. (306 aa) |
| | Arad_2756 | Adenylate cyclase protein. (352 aa) |
| | iunH2 | Inosine-uridine preferring nucleoside hydrolase protein. (301 aa) |
| | prsAch | Ribose-phosphate pyrophosphokinase protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (180 aa) |
| | ade-3 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (570 aa) |
| | xdhA | Xanthine dehydrogenase protein. (490 aa) |
| | xdhB | Xanthine dehydrogenase, molybdopterin binding subunit. (778 aa) |
| | guaD | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (431 aa) |
| | Arad_3324 | Conserved hypothetical protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (118 aa) |
| | allA | Ureidoglycolate hydrolase protein; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (175 aa) |
| | ureC | Urease (urea amidohydrolase) alpha subunit protein; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (569 aa) |
| | ureB | Urease (urea amidohydrolase) beta subunit protein; Belongs to the urease beta subunit family. (101 aa) |
| | ureA | Urease (urea amidohydrolase) gamma subunit protein; Belongs to the urease gamma subunit family. (100 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa) |
| | cyaG1 | Adenylate cyclase protein. (403 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (352 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (479 aa) |
| | purN-2 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (199 aa) |
| | Arad_3820 | 5-nucleotidase protein; Belongs to the 5'-nucleotidase family. (681 aa) |
| | pgm | Phosphoglucomutase protein. (542 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa) |
| | guaA2 | GMP synthase - glutamine amidotransferase protein. (244 aa) |
| | Arad_4584 | Oxidoreductase. (762 aa) |
| | Arad_4585 | Oxidoreductase, molybdopterin binding subunit. (327 aa) |
| | xdhA-4 | Xanthine dehydrogenase protein. (164 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH. (538 aa) |
| | Arad_7134 | Hydantoin racemase protein. (234 aa) |
| | Arad_7142 | Conserved hypothetical protein. (273 aa) |
| | Arad_7290 | Adenylate cyclase protein. (399 aa) |
| | Arad_7431 | Xanthine dehydrogenase protein. (731 aa) |
| | Arad_7432 | Oxidoreductase, molybdopterin-binding subunit. (316 aa) |
| | Arad_7433 | Xanthine dehydrogenase protein, iron-sulfur-binding subunit. (211 aa) |
| | Arad_7549 | Adenylate cyclase protein. (425 aa) |
| | Arad_7898 | Adenylate cyclase protein. (736 aa) |
| | Arad_7954 | Oxidoreductase protein. (496 aa) |
| | cyaD | Adenylate cyclase protein. (723 aa) |
| | nrdF | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (329 aa) |
| | Arad_8250 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (717 aa) |
| | guaD-2 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (452 aa) |
| | ade-4 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (599 aa) |
| | Arad_9078 | Hydantoin racemase protein. (243 aa) |
| | cyaCe | Adenylate cyclase protein. (574 aa) |
| | cyaA | Adenylate cyclase protein. (445 aa) |
| | iunH2-2 | Inosine-uridine preferring nucleoside hydrolase protein. (332 aa) |
| | Arad_9877 | Xanthine dehydrogenase protein. (1499 aa) |
| | Arad_9888 | Oxidoreductase protein. (489 aa) |
