(26 nodes) RNA Polymerase II Transcription Elongation, and FACT complex network (Tetrahymena thermophila)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A4VCX5_TETTS	Uncharacterized protein. (1127 aa)
	I7LT54_TETTS	Transcription factor S-II. (321 aa)
	I7LVC3_TETTS	NLI interacting factor-like phosphatase. (874 aa)
	I7M1Z2_TETTS	Transmembrane protein, putative. (1028 aa)
	I7M611_TETTS	RNA pol II accessory factor, Cdc73 family protein. (395 aa)
	I7M8E8_TETTS	Metallopeptidase family M24 containing protein. (1008 aa)
	I7M904_TETTS	Transmembrane protein, putative. (1660 aa)
	I7M9Q1_TETTS	Plus-3 domain protein. (481 aa)
	I7MA57_TETTS	RNA polymerase rpb8. (130 aa)
	I7MET8_TETTS	TFIIS helical bundle-like domain protein. (249 aa)
	I7MGF4_TETTS	Uncharacterized protein. (1890 aa)
	Q229U1_TETTS	Tetratricopeptide repeat protein. (1137 aa)
	Q22BP0_TETTS	Zinc knuckle protein. (1504 aa)
	Q22N16_TETTS	Transcription elongation factor spt5. (778 aa)
	Q22S21_TETTS	Tetratricopeptide repeat protein. (260 aa)
	Q22Y09_TETTS	NLI interacting factor-like phosphatase. (540 aa)
	Q23D83_TETTS	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (437 aa)
	Q23E88_TETTS	Kinase domain protein. (447 aa)
	Q23G24_TETTS	Transmembrane protein, putative. (1024 aa)
	Q23QF5_TETTS	High mobility group (HMG) box protein. (249 aa)
	Q23U98_TETTS	DNA-directed RNA polymerase, beta subunit. (312 aa)
	Q240I8_TETTS	Uncharacterized protein. (1489 aa)
	Q24FV0_TETTS	RNA polymerase Rpb5, carboxy-terminal domain protein. (275 aa)
	Q24GF3_TETTS	Amine-terminal domain cyclin. (313 aa)
	W7WXG3_TETTS	DNA-directed RNA polymerase II 13.3 kDa proteinRPB11. (183 aa)
	W7XDW4_TETTS	F-box protein, putative. (298 aa)

Your Current Organism:

Tetrahymena thermophila

NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A4VCX5_TETTS	I7LT54_TETTS	A4VCX5	I7LT54	Uncharacterized protein.	Transcription factor S-II.	0.849
A4VCX5_TETTS	I7LVC3_TETTS	A4VCX5	I7LVC3	Uncharacterized protein.	NLI interacting factor-like phosphatase.	0.621
A4VCX5_TETTS	I7M1Z2_TETTS	A4VCX5	I7M1Z2	Uncharacterized protein.	Transmembrane protein, putative.	0.509
A4VCX5_TETTS	I7M611_TETTS	A4VCX5	I7M611	Uncharacterized protein.	RNA pol II accessory factor, Cdc73 family protein.	0.890
A4VCX5_TETTS	I7M8E8_TETTS	A4VCX5	I7M8E8	Uncharacterized protein.	Metallopeptidase family M24 containing protein.	0.958
A4VCX5_TETTS	I7M9Q1_TETTS	A4VCX5	I7M9Q1	Uncharacterized protein.	Plus-3 domain protein.	0.885
A4VCX5_TETTS	I7MA57_TETTS	A4VCX5	I7MA57	Uncharacterized protein.	RNA polymerase rpb8.	0.613
A4VCX5_TETTS	I7MET8_TETTS	A4VCX5	I7MET8	Uncharacterized protein.	TFIIS helical bundle-like domain protein.	0.966
A4VCX5_TETTS	I7MGF4_TETTS	A4VCX5	I7MGF4	Uncharacterized protein.	Uncharacterized protein.	0.509
A4VCX5_TETTS	Q229U1_TETTS	A4VCX5	Q229U1	Uncharacterized protein.	Tetratricopeptide repeat protein.	0.759
A4VCX5_TETTS	Q22N16_TETTS	A4VCX5	Q22N16	Uncharacterized protein.	Transcription elongation factor spt5.	0.924
A4VCX5_TETTS	Q22S21_TETTS	A4VCX5	Q22S21	Uncharacterized protein.	Tetratricopeptide repeat protein.	0.759
A4VCX5_TETTS	Q22Y09_TETTS	A4VCX5	Q22Y09	Uncharacterized protein.	NLI interacting factor-like phosphatase.	0.621
A4VCX5_TETTS	Q23D83_TETTS	A4VCX5	Q23D83	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.864
A4VCX5_TETTS	Q23G24_TETTS	A4VCX5	Q23G24	Uncharacterized protein.	Transmembrane protein, putative.	0.509
A4VCX5_TETTS	Q23QF5_TETTS	A4VCX5	Q23QF5	Uncharacterized protein.	High mobility group (HMG) box protein.	0.864
A4VCX5_TETTS	Q23U98_TETTS	A4VCX5	Q23U98	Uncharacterized protein.	DNA-directed RNA polymerase, beta subunit.	0.579
A4VCX5_TETTS	Q240I8_TETTS	A4VCX5	Q240I8	Uncharacterized protein.	Uncharacterized protein.	0.509
A4VCX5_TETTS	Q24FV0_TETTS	A4VCX5	Q24FV0	Uncharacterized protein.	RNA polymerase Rpb5, carboxy-terminal domain protein.	0.888
A4VCX5_TETTS	W7WXG3_TETTS	A4VCX5	W7WXG3	Uncharacterized protein.	DNA-directed RNA polymerase II 13.3 kDa proteinRPB11.	0.820