(20 nodes) Regulation of protein-containing complex assembly network (Tetrahymena thermophila)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	Q244Y3_TETTS	Tubulin polymerization-promoting family protein. (149 aa)
	Q24FQ8_TETTS	Microtubule-binding protein MIP-T3. (451 aa)
	W7X8T2_TETTS	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (296 aa)
	W7XFP4_TETTS	Glycine cleavage H-protein. (227 aa)
	Q234F5_TETTS	Profilin; Belongs to the profilin family. (152 aa)
	Q236Q0_TETTS	Uncharacterized protein. (1244 aa)
	Q23F87_TETTS	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	Q23R52_TETTS	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	I7MLV8_TETTS	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	Q22LY3_TETTS	Uncharacterized protein. (144 aa)
	Q244Y1_TETTS	Tubulin polymerization-promoting family protein. (149 aa)
	Q22LY4_TETTS	Uncharacterized protein. (144 aa)
	Q22LY5_TETTS	Uncharacterized protein. (144 aa)
	Q22NV2_TETTS	Microtubule-binding calmodulin-regulated spectrin-associated protein. (1770 aa)
	I7LUJ4_TETTS	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (176 aa)
	Q22VA4_TETTS	WD domain, G-beta repeat protein. (365 aa)
	Q22Y88_TETTS	Actin-related protein 2/3 complex subunit 1A/1B. (400 aa)
	I7MH68_TETTS	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (342 aa)
	I7MIP8_TETTS	Ankyrin domain protein. (305 aa)
	Q231P6_TETTS	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (279 aa)

Your Current Organism:

Tetrahymena thermophila

NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I7LUJ4_TETTS	I7MH68_TETTS	I7LUJ4	I7MH68	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.999
I7LUJ4_TETTS	Q22Y88_TETTS	I7LUJ4	Q22Y88	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 1A/1B.	0.999
I7LUJ4_TETTS	Q231P6_TETTS	I7LUJ4	Q231P6	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.791
I7LUJ4_TETTS	W7X8T2_TETTS	I7LUJ4	W7X8T2	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.696
I7MH68_TETTS	I7LUJ4_TETTS	I7MH68	I7LUJ4	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.999
I7MH68_TETTS	Q22Y88_TETTS	I7MH68	Q22Y88	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 1A/1B.	0.999
I7MH68_TETTS	Q231P6_TETTS	I7MH68	Q231P6	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.799
I7MH68_TETTS	Q234F5_TETTS	I7MH68	Q234F5	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Profilin; Belongs to the profilin family.	0.513
I7MH68_TETTS	W7X8T2_TETTS	I7MH68	W7X8T2	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.557
I7MIP8_TETTS	Q231P6_TETTS	I7MIP8	Q231P6	Ankyrin domain protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.939
I7MIP8_TETTS	Q24FQ8_TETTS	I7MIP8	Q24FQ8	Ankyrin domain protein.	Microtubule-binding protein MIP-T3.	0.414
I7MIP8_TETTS	W7X8T2_TETTS	I7MIP8	W7X8T2	Ankyrin domain protein.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.812
I7MLV8_TETTS	Q22VA4_TETTS	I7MLV8	Q22VA4	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family.	WD domain, G-beta repeat protein.	0.993
I7MLV8_TETTS	Q23F87_TETTS	I7MLV8	Q23F87	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family.	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family.	0.902
I7MLV8_TETTS	Q23R52_TETTS	I7MLV8	Q23R52	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family.	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family.	0.900
Q22VA4_TETTS	I7MLV8_TETTS	Q22VA4	I7MLV8	WD domain, G-beta repeat protein.	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family.	0.993
Q22VA4_TETTS	Q23F87_TETTS	Q22VA4	Q23F87	WD domain, G-beta repeat protein.	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family.	0.993
Q22VA4_TETTS	Q23R52_TETTS	Q22VA4	Q23R52	WD domain, G-beta repeat protein.	ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. SAR1 family.	0.993
Q22Y88_TETTS	I7LUJ4_TETTS	Q22Y88	I7LUJ4	Actin-related protein 2/3 complex subunit 1A/1B.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.999
Q22Y88_TETTS	I7MH68_TETTS	Q22Y88	I7MH68	Actin-related protein 2/3 complex subunit 1A/1B.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.999