STRINGSTRING
EAR24320.1 EAR24320.1 EAR24041.1 EAR24041.1 nrdR nrdR EAR26023.1 EAR26023.1 dcd dcd EAR26025.1 EAR26025.1 EAR26026.1 EAR26026.1 EAR26027.1 EAR26027.1 serS serS EAR23966.1 EAR23966.1 ribH ribH ribA ribA EAR24172.1 EAR24172.1 EAR24173.1 EAR24173.1 EAR24175.1 EAR24175.1 trpS trpS EAR24178.1 EAR24178.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EAR24320.1Hypothetical protein; COG1985 Pyrimidine reductase, riboflavin biosynthesis. (255 aa)
EAR24041.1Flavin-dependent reductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. (167 aa)
nrdRHypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes. (98 aa)
EAR26023.1Deoxycytidine triphosphate deaminase. (219 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (201 aa)
EAR26025.1Riboflavin biosynthesis protein RibF (riboflavin kinase); COG0196 FAD synthase. (147 aa)
EAR26026.1Putative oxidoreductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. (164 aa)
EAR26027.1Hypothetical protein; COG1695 Predicted transcriptional regulators. (199 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (421 aa)
EAR23966.1Hypothetical protein; COG0561 Predicted hydrolases of the HAD superfamily. (271 aa)
ribHRiboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (157 aa)
ribA3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (430 aa)
EAR24172.1COG0307 Riboflavin synthase alpha chain. (207 aa)
EAR24173.1Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (345 aa)
EAR24175.1COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins. (188 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (336 aa)
EAR24178.1Narrowly hypothetical protein; COG1295 Predicted membrane protein. (355 aa)
Your Current Organism:
actinobacterium PHSC20C1
NCBI taxonomy Id: 312284
Other names: m. actinobacterium PHSC20C1, marine actinobacterium PHSC20C1, marine actinobacterium str. PHSC20C1, marine actinobacterium strain PHSC20C1
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