STRINGSTRING
rpoN rpoN VF_1390 VF_1390 polB polB litR litR rpoD rpoD hfq hfq acs acs lexA lexA luxI luxI luxR luxR rpoQ rpoQ VF_A1016 VF_A1016 VF_A1017 VF_A1017 luxU luxU luxO luxO luxP luxP chiA chiA luxS luxS VF_0986 VF_0986 ainR ainR ainS ainS VF_1059 VF_1059 VF_1146 VF_1146
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpoNRNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (489 aa)
VF_1390Carbohydrate binding domain protein. (563 aa)
polBDNA polymerase II. (781 aa)
litRQuorum sensing transcriptional regulator LitR (HapR). (201 aa)
rpoDRNA polymerase, sigma-70 (sigma-D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (613 aa)
hfqRNA chaperone Hfq (HF-I); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (88 aa)
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
lexADNA-binding transcriptional repressor of SOS regulon; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (208 aa)
luxI3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. (190 aa)
luxRAutoinducer-binding transcriptional activator protein LuxR; Transcriptional activator of the bioluminescence operon. Binds to the OHHL autoinducer. (250 aa)
rpoQsigma-Q factor RpoQ, quorum-sensing regulated RpoS-like sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (294 aa)
VF_A1016Two component sensory histidine kinase. (864 aa)
VF_A1017Two component response regulator. (572 aa)
luxUAutoinducer phosphorelay protein LuxU. (118 aa)
luxOAutoinducer repressor protein LuxO. (476 aa)
luxPPeriplasmic AI-2 binding protein LuxP. (372 aa)
chiAEndochitinase. (846 aa)
luxSS-ribosylhomocysteinase, autoinducer-2 synthase protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (172 aa)
VF_0986Chitodextrinase. (1053 aa)
ainRPutative autoinducer regulatory protein AinR. (819 aa)
ainSC8-HSL autoinducer synthesis protein AinS. (380 aa)
VF_1059Basic endochitinase. (555 aa)
VF_1146Chitodextrinase precursor. (789 aa)
Your Current Organism:
Aliivibrio fischeri
NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114
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