STRINGSTRING
luxS luxS VF_1598 VF_1598 qsrP qsrP sypG sypG rpoQ rpoQ luxR luxR luxI luxI luxA luxA luxB luxB luxG luxG acs acs litR litR arcB arcB flaF flaF phoB phoB phoR phoR flaA flaA flaB flaB flaC flaC flaD flaD flaE flaE cheA cheA ainS ainS luxU luxU luxO luxO luxQ luxQ luxP luxP chiA chiA ainR ainR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
luxSS-ribosylhomocysteinase, autoinducer-2 synthase protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (172 aa)
VF_1598Exochitinase. (845 aa)
qsrPLuxR-regulated periplasmic protein QsrP. (131 aa)
sypGSigma-54 dependent transcriptional regulator; Syp polysaccharide locus. (500 aa)
rpoQsigma-Q factor RpoQ, quorum-sensing regulated RpoS-like sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (294 aa)
luxRAutoinducer-binding transcriptional activator protein LuxR; Transcriptional activator of the bioluminescence operon. Binds to the OHHL autoinducer. (250 aa)
luxI3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. (190 aa)
luxALuciferase alpha chain LuxA. (355 aa)
luxBLuciferase beta chain LuxB. (326 aa)
luxGNAD(P)H-dependent FMN reductase LuxG. (236 aa)
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
litRQuorum sensing transcriptional regulator LitR (HapR). (201 aa)
arcBHybrid sensory histidine kinase in two-component regulatory system with ArcA. (788 aa)
flaFFlagellin FlaF; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (377 aa)
phoBDNA-binding response regulator in two-component regulatory system with PhoR. (230 aa)
phoRSensory histidine kinase in two-component regulatory system with PhoB. (431 aa)
flaAFlagellin FlaA; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (379 aa)
flaBFlagellin FlaB; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (377 aa)
flaCFlagellin FlaC; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (377 aa)
flaDFlagellin FlaD; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (375 aa)
flaEFlagellin FlaE; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (398 aa)
cheAChemotactic sensory histidine kinase CheA, in two-component regulatory system with CheB and CheY. (735 aa)
ainSC8-HSL autoinducer synthesis protein AinS. (380 aa)
luxUAutoinducer phosphorelay protein LuxU. (118 aa)
luxOAutoinducer repressor protein LuxO. (476 aa)
luxQMembrane-bound sensor histidine kinase LuxQ. (744 aa)
luxPPeriplasmic AI-2 binding protein LuxP. (372 aa)
chiAEndochitinase. (846 aa)
ainRPutative autoinducer regulatory protein AinR. (819 aa)
Your Current Organism:
Aliivibrio fischeri
NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114
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