23 items (Aliivibrio fischeri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	rpoD	RNA polymerase, sigma-70 (sigma-D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (613 aa)
	leuO	DNA-binding transcriptional activator; Belongs to the LysR transcriptional regulatory family. (323 aa)
	rpoB	RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa)
	rpoH	RNA polymerase, sigma-32 (sigma-H) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (286 aa)
	rscS	Hybrid sensor kinase RscS; Activator of syp locus genes. (927 aa)
	pyrC	Dihydro-orotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (342 aa)
	rstB	RstB2 protein; Cryptic phage CTXphi. (108 aa)
	rstR	Transcriptional repressor rstR; Cryptic phage CTXphi. (111 aa)
	tcpA	Toxin coregulated pilin subunit precursor TcpA. (208 aa)
	rpoQ	sigma-Q factor RpoQ, quorum-sensing regulated RpoS-like sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (294 aa)
	glnA	Glutamine synthetase. (469 aa)
	mdh	Malate dehydrogenase, NAD(P)-binding; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa)
	rpoN	RNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (489 aa)
	nanA	N-acetylneuraminate lyase. (297 aa)
	toxR	Transcriptional activator ToxR. (293 aa)
	luxO	Autoinducer repressor protein LuxO. (476 aa)
	rplT	50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa)
	uup	Fused predicted transporter subunits of ABC superfamily: ATP-binding components. (636 aa)
	fliA	RNA polymerase, sigma-28 (sigma-F, FliA) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (243 aa)
	rpoS	RNA polymerase, sigma-S (sigma-38) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (321 aa)
	rpoE	RNA polymerase, sigma-24 (sigma-E) factor; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
	chiS	Chitin sensor histidine kinase ChiS. (1126 aa)
	litR	Quorum sensing transcriptional regulator LitR (HapR). (201 aa)

Your Current Organism:

Aliivibrio fischeri

NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
chiS	rscS	VF_2138	VF_A0237	Chitin sensor histidine kinase ChiS.	Hybrid sensor kinase RscS; Activator of syp locus genes.	0.989
fliA	rpoB	VF_1834	VF_2414	RNA polymerase, sigma-28 (sigma-F, FliA) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.	RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.891
fliA	rpoD	VF_1834	VF_2254	RNA polymerase, sigma-28 (sigma-F, FliA) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.	RNA polymerase, sigma-70 (sigma-D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.463
fliA	rpoH	VF_1834	VF_2450	RNA polymerase, sigma-28 (sigma-F, FliA) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.	RNA polymerase, sigma-32 (sigma-H) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.	0.562
fliA	rpoN	VF_1834	VF_0387	RNA polymerase, sigma-28 (sigma-F, FliA) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.	RNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.655
fliA	rpoQ	VF_1834	VF_A1015	RNA polymerase, sigma-28 (sigma-F, FliA) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.	sigma-Q factor RpoQ, quorum-sensing regulated RpoS-like sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.421
fliA	rpoS	VF_1834	VF_2067	RNA polymerase, sigma-28 (sigma-F, FliA) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.	RNA polymerase, sigma-S (sigma-38) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	0.488
fliA	rscS	VF_1834	VF_A0237	RNA polymerase, sigma-28 (sigma-F, FliA) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.	Hybrid sensor kinase RscS; Activator of syp locus genes.	0.598
glnA	rpoB	VF_0098	VF_2414	Glutamine synthetase.	RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.505
glnA	rscS	VF_0098	VF_A0237	Glutamine synthetase.	Hybrid sensor kinase RscS; Activator of syp locus genes.	0.411
leuO	rpoE	VF_2265	VF_2093	DNA-binding transcriptional activator; Belongs to the LysR transcriptional regulatory family.	RNA polymerase, sigma-24 (sigma-E) factor; Belongs to the sigma-70 factor family. ECF subfamily.	0.455
leuO	rpoH	VF_2265	VF_2450	DNA-binding transcriptional activator; Belongs to the LysR transcriptional regulatory family.	RNA polymerase, sigma-32 (sigma-H) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.	0.500
leuO	toxR	VF_2265	VF_0791	DNA-binding transcriptional activator; Belongs to the LysR transcriptional regulatory family.	Transcriptional activator ToxR.	0.699
litR	luxO	VF_2177	VF_0937	Quorum sensing transcriptional regulator LitR (HapR).	Autoinducer repressor protein LuxO.	0.770
litR	rpoD	VF_2177	VF_2254	Quorum sensing transcriptional regulator LitR (HapR).	RNA polymerase, sigma-70 (sigma-D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.460
litR	rpoQ	VF_2177	VF_A1015	Quorum sensing transcriptional regulator LitR (HapR).	sigma-Q factor RpoQ, quorum-sensing regulated RpoS-like sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.597
litR	rpoS	VF_2177	VF_2067	Quorum sensing transcriptional regulator LitR (HapR).	RNA polymerase, sigma-S (sigma-38) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	0.548
luxO	litR	VF_0937	VF_2177	Autoinducer repressor protein LuxO.	Quorum sensing transcriptional regulator LitR (HapR).	0.770
luxO	rpoN	VF_0937	VF_0387	Autoinducer repressor protein LuxO.	RNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.936
luxO	rpoQ	VF_0937	VF_A1015	Autoinducer repressor protein LuxO.	sigma-Q factor RpoQ, quorum-sensing regulated RpoS-like sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.466

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