node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
lsrR | luxI | VF_A0400 | VF_A0924 | Transcriptional repressor. | 3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. | 0.497 |
lsrR | luxO | VF_A0400 | VF_0937 | Transcriptional repressor. | Autoinducer repressor protein LuxO. | 0.495 |
lsrR | luxP | VF_A0400 | VF_0707 | Transcriptional repressor. | Periplasmic AI-2 binding protein LuxP. | 0.660 |
lsrR | luxQ | VF_A0400 | VF_0708 | Transcriptional repressor. | Membrane-bound sensor histidine kinase LuxQ. | 0.504 |
lsrR | luxR | VF_A0400 | VF_A0925 | Transcriptional repressor. | Autoinducer-binding transcriptional activator protein LuxR; Transcriptional activator of the bioluminescence operon. Binds to the OHHL autoinducer. | 0.499 |
lsrR | luxS | VF_A0400 | VF_0545 | Transcriptional repressor. | S-ribosylhomocysteinase, autoinducer-2 synthase protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.782 |
lsrR | luxU | VF_A0400 | VF_0938 | Transcriptional repressor. | Autoinducer phosphorelay protein LuxU. | 0.495 |
luxI | lsrR | VF_A0924 | VF_A0400 | 3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. | Transcriptional repressor. | 0.497 |
luxI | luxO | VF_A0924 | VF_0937 | 3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. | Autoinducer repressor protein LuxO. | 0.700 |
luxI | luxP | VF_A0924 | VF_0707 | 3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. | Periplasmic AI-2 binding protein LuxP. | 0.693 |
luxI | luxQ | VF_A0924 | VF_0708 | 3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. | Membrane-bound sensor histidine kinase LuxQ. | 0.630 |
luxI | luxR | VF_A0924 | VF_A0925 | 3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. | Autoinducer-binding transcriptional activator protein LuxR; Transcriptional activator of the bioluminescence operon. Binds to the OHHL autoinducer. | 0.999 |
luxI | luxS | VF_A0924 | VF_0545 | 3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. | S-ribosylhomocysteinase, autoinducer-2 synthase protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.792 |
luxI | luxU | VF_A0924 | VF_0938 | 3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. | Autoinducer phosphorelay protein LuxU. | 0.694 |
luxO | lsrR | VF_0937 | VF_A0400 | Autoinducer repressor protein LuxO. | Transcriptional repressor. | 0.495 |
luxO | luxI | VF_0937 | VF_A0924 | Autoinducer repressor protein LuxO. | 3-oxo-C6-HSL autoinducer synthesis protein LuxI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation. | 0.700 |
luxO | luxP | VF_0937 | VF_0707 | Autoinducer repressor protein LuxO. | Periplasmic AI-2 binding protein LuxP. | 0.821 |
luxO | luxQ | VF_0937 | VF_0708 | Autoinducer repressor protein LuxO. | Membrane-bound sensor histidine kinase LuxQ. | 0.868 |
luxO | luxR | VF_0937 | VF_A0925 | Autoinducer repressor protein LuxO. | Autoinducer-binding transcriptional activator protein LuxR; Transcriptional activator of the bioluminescence operon. Binds to the OHHL autoinducer. | 0.703 |
luxO | luxS | VF_0937 | VF_0545 | Autoinducer repressor protein LuxO. | S-ribosylhomocysteinase, autoinducer-2 synthase protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.821 |