(7 nodes) Mixed, incl. Mitogen-activated protein (MAP) kinase phosphatase, and Activation of the AP-1 family of transcription factors network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cre-jun-1	CRE-JUN-1 protein. (317 aa)
	Cre-fos-1	CRE-FOS-1 protein. (472 aa)
	Cre-vhp-1	CRE-VHP-1 protein. (650 aa)
	Cre-pmk-1	Mitogen-activated protein kinase. (381 aa)
	CRE_28791	Protein kinase domain-containing protein. (388 aa)
	CRE_07764	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (383 aa)
	CRE_29272	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (338 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_07764	CRE_28791	E3N6S0	E3MK34	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.686
CRE_07764	CRE_29272	E3N6S0	E3NQ78	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.980
CRE_07764	Cre-fos-1	E3N6S0	E3LUK2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	CRE-FOS-1 protein.	0.888
CRE_07764	Cre-jun-1	E3N6S0	E3LG72	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	CRE-JUN-1 protein.	0.824
CRE_07764	Cre-pmk-1	E3N6S0	E3M6N8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.766
CRE_07764	Cre-vhp-1	E3N6S0	E3M4I9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	CRE-VHP-1 protein.	0.968
CRE_28791	CRE_07764	E3MK34	E3N6S0	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.686
CRE_28791	CRE_29272	E3MK34	E3NQ78	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.772
CRE_28791	Cre-fos-1	E3MK34	E3LUK2	Protein kinase domain-containing protein.	CRE-FOS-1 protein.	0.898
CRE_28791	Cre-jun-1	E3MK34	E3LG72	Protein kinase domain-containing protein.	CRE-JUN-1 protein.	0.939
CRE_28791	Cre-pmk-1	E3MK34	E3M6N8	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.702
CRE_28791	Cre-vhp-1	E3MK34	E3M4I9	Protein kinase domain-containing protein.	CRE-VHP-1 protein.	0.964
CRE_29272	CRE_07764	E3NQ78	E3N6S0	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.980
CRE_29272	CRE_28791	E3NQ78	E3MK34	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein kinase domain-containing protein.	0.772
CRE_29272	Cre-fos-1	E3NQ78	E3LUK2	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	CRE-FOS-1 protein.	0.408
CRE_29272	Cre-pmk-1	E3NQ78	E3M6N8	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.964
CRE_29272	Cre-vhp-1	E3NQ78	E3M4I9	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	CRE-VHP-1 protein.	0.912
Cre-fos-1	CRE_07764	E3LUK2	E3N6S0	CRE-FOS-1 protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.888
Cre-fos-1	CRE_28791	E3LUK2	E3MK34	CRE-FOS-1 protein.	Protein kinase domain-containing protein.	0.898
Cre-fos-1	CRE_29272	E3LUK2	E3NQ78	CRE-FOS-1 protein.	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.408