(42 nodes) Ribosomal large subunit biogenesis, and Nucleolar protein,Nop52 network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRE_01895	Brix domain-containing protein. (382 aa)
	CRE_01896	Uncharacterized protein. (160 aa)
	Cre-nst-1	CRE-NST-1 protein. (555 aa)
	Cre-puf-12	CRE-PUF-12 protein. (762 aa)
	Cre-pro-2	CRE-PRO-2 protein. (720 aa)
	CRE_18594	Nucleolar complex protein 3 homolog. (796 aa)
	CRE_18798	Uncharacterized protein. (188 aa)
	CRE_26449	Uncharacterized protein. (154 aa)
	CRE_26336	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (672 aa)
	CRE_26346	Uncharacterized protein. (606 aa)
	CRE_25342	RNA helicase. (577 aa)
	CRE_29809	RNA helicase. (578 aa)
	CRE_02956	Protein MAK16 homolog; Belongs to the MAK16 family. (321 aa)
	CRE_03826	Uncharacterized protein. (761 aa)
	Cre-tag-345	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family. (453 aa)
	CRE_03900	Uncharacterized protein; Belongs to the DEAD box helicase family. (749 aa)
	Cre-ngp-1	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (652 aa)
	CRE_05616	Uncharacterized protein. (584 aa)
	Cre-rpl-24.2	CRE-RPL-24.2 protein. (162 aa)
	CRE_11726	SURF6 domain-containing protein. (449 aa)
	CRE_11813	Uncharacterized protein. (348 aa)
	CRE_14053	Uncharacterized protein. (259 aa)
	CRE_20239	RRM domain-containing protein. (334 aa)
	CRE_21219	Uncharacterized protein. (448 aa)
	CRE_24526	Brix domain-containing protein. (352 aa)
	CRE_24023	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	CRE_29972	Uncharacterized protein. (400 aa)
	CRE_05012	Uncharacterized protein. (119 aa)
	CRE_06776	Brix domain-containing protein. (398 aa)
	CRE_15490	Uncharacterized protein. (393 aa)
	CRE_22988	Uncharacterized protein. (110 aa)
	CRE_29065	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (784 aa)
	Cre-lpd-7	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (531 aa)
	CRE_31365	Uncharacterized protein. (124 aa)
	Cre-lpd-6	CRE-LPD-6 protein. (586 aa)
	CRE_30102	Brix domain-containing protein. (300 aa)
	Cre-nol-1	CRE-NOL-1 protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (677 aa)
	CRE_07879	Uncharacterized protein. (415 aa)
	CRE_04391	Uncharacterized protein. (633 aa)
	CRE_14378	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (684 aa)
	CRE_26887	Brix domain-containing protein. (269 aa)
	CRE_16572	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (435 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_01895	CRE_01896	E3LG46	E3LG47	Brix domain-containing protein.	Uncharacterized protein.	0.450
CRE_01895	CRE_02956	E3LG46	E3LWW9	Brix domain-containing protein.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.990
CRE_01895	CRE_03826	E3LG46	E3LXB6	Brix domain-containing protein.	Uncharacterized protein.	0.786
CRE_01895	CRE_03900	E3LG46	E3LXQ6	Brix domain-containing protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.693
CRE_01895	CRE_04391	E3LG46	E3NLI4	Brix domain-containing protein.	Uncharacterized protein.	0.787
CRE_01895	CRE_05012	E3LG46	E3MNH0	Brix domain-containing protein.	Uncharacterized protein.	0.685
CRE_01895	CRE_05616	E3LG46	E3M0A7	Brix domain-containing protein.	Uncharacterized protein.	0.986
CRE_01895	CRE_06776	E3LG46	E3MP24	Brix domain-containing protein.	Brix domain-containing protein.	0.937
CRE_01895	CRE_07879	E3LG46	E3NL48	Brix domain-containing protein.	Uncharacterized protein.	0.963
CRE_01895	CRE_11726	E3LG46	E3M4B3	Brix domain-containing protein.	SURF6 domain-containing protein.	0.976
CRE_01895	CRE_11813	E3LG46	E3M4U6	Brix domain-containing protein.	Uncharacterized protein.	0.991
CRE_01895	CRE_14053	E3LG46	E3M908	Brix domain-containing protein.	Uncharacterized protein.	0.994
CRE_01895	CRE_14378	E3LG46	E3NM67	Brix domain-containing protein.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.885
CRE_01895	CRE_15490	E3LG46	E3MSW6	Brix domain-containing protein.	Uncharacterized protein.	0.698
CRE_01895	CRE_16572	E3LG46	E3NU08	Brix domain-containing protein.	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.950
CRE_01895	CRE_18594	E3LG46	E3LK17	Brix domain-containing protein.	Nucleolar complex protein 3 homolog.	0.950
CRE_01895	CRE_18798	E3LG46	E3LKH0	Brix domain-containing protein.	Uncharacterized protein.	0.977
CRE_01895	CRE_20239	E3LG46	E3MCU7	Brix domain-containing protein.	RRM domain-containing protein.	0.995
CRE_01895	CRE_21219	E3LG46	E3MEX1	Brix domain-containing protein.	Uncharacterized protein.	0.989
CRE_01895	CRE_22988	E3LG46	E3MW84	Brix domain-containing protein.	Uncharacterized protein.	0.938