(12 nodes) Mixed, incl. Interleukin-15 signaling, and Growth factor receptor domain 4 network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRE_00009	Uncharacterized protein. (230 aa)
	CRE_00559	Uncharacterized protein. (293 aa)
	CRE_00742	Uncharacterized protein. (892 aa)
	Cre-sos-1	CRE-SOS-1 protein. (1484 aa)
	CRE_27356	Uncharacterized protein. (212 aa)
	Cre-abl-1	Tyrosine-protein kinase. (1287 aa)
	Cre-sli-1	CRE-SLI-1 protein. (537 aa)
	Cre-shc-1	CRE-SHC-1 protein. (323 aa)
	Cre-kin-32	CRE-KIN-32 protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (868 aa)
	Cre-ced-2	CRE-CED-2 protein. (294 aa)
	Cre-let-23	Receptor protein-tyrosine kinase. (1264 aa)
	CRE_22667	Uncharacterized protein. (632 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_00009	CRE_00742	E3LCA5	E3LE36	Uncharacterized protein.	Uncharacterized protein.	0.923
CRE_00009	CRE_22667	E3LCA5	E3NFJ5	Uncharacterized protein.	Uncharacterized protein.	0.987
CRE_00009	CRE_27356	E3LCA5	E3LPX8	Uncharacterized protein.	Uncharacterized protein.	0.893
CRE_00009	Cre-abl-1	E3LCA5	E3M213	Uncharacterized protein.	Tyrosine-protein kinase.	0.924
CRE_00009	Cre-ced-2	E3LCA5	E3N5V4	Uncharacterized protein.	CRE-CED-2 protein.	0.909
CRE_00009	Cre-kin-32	E3LCA5	E3MX80	Uncharacterized protein.	CRE-KIN-32 protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.993
CRE_00009	Cre-let-23	E3LCA5	E3NAV2	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.987
CRE_00009	Cre-shc-1	E3LCA5	E3MFM3	Uncharacterized protein.	CRE-SHC-1 protein.	0.992
CRE_00009	Cre-sli-1	E3LCA5	E3MA78	Uncharacterized protein.	CRE-SLI-1 protein.	0.998
CRE_00009	Cre-sos-1	E3LCA5	E3LKI9	Uncharacterized protein.	CRE-SOS-1 protein.	0.998
CRE_00559	CRE_00742	E3LD35	E3LE36	Uncharacterized protein.	Uncharacterized protein.	0.923
CRE_00559	CRE_22667	E3LD35	E3NFJ5	Uncharacterized protein.	Uncharacterized protein.	0.987
CRE_00559	CRE_27356	E3LD35	E3LPX8	Uncharacterized protein.	Uncharacterized protein.	0.894
CRE_00559	Cre-abl-1	E3LD35	E3M213	Uncharacterized protein.	Tyrosine-protein kinase.	0.924
CRE_00559	Cre-ced-2	E3LD35	E3N5V4	Uncharacterized protein.	CRE-CED-2 protein.	0.909
CRE_00559	Cre-kin-32	E3LD35	E3MX80	Uncharacterized protein.	CRE-KIN-32 protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.993
CRE_00559	Cre-let-23	E3LD35	E3NAV2	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.987
CRE_00559	Cre-shc-1	E3LD35	E3MFM3	Uncharacterized protein.	CRE-SHC-1 protein.	0.992
CRE_00559	Cre-sli-1	E3LD35	E3MA78	Uncharacterized protein.	CRE-SLI-1 protein.	0.998
CRE_00559	Cre-sos-1	E3LD35	E3LKI9	Uncharacterized protein.	CRE-SOS-1 protein.	0.998