(17 nodes) Negative regulation of canonical Wnt signaling pathway, and Proximal/distal pattern formation network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cre-bar-1	CRE-BAR-1 protein. (811 aa)
	Cre-pry-1	CRE-PRY-1 protein. (643 aa)
	Cre-lin-23	CRE-LIN-23 protein. (672 aa)
	Cre-cbp-1	CRE-CBP-1 protein. (2042 aa)
	Cre-axl-1	CRE-AXL-1 protein. (398 aa)
	Cre-lit-1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (597 aa)
	Cre-wrm-1	CRE-WRM-1 protein. (789 aa)
	Cre-sys-1	CRE-SYS-1 protein. (846 aa)
	CRE_11693	Protein kinase domain-containing protein. (368 aa)
	Cre-kin-19	CRE-KIN-19 protein; Belongs to the protein kinase superfamily. (341 aa)
	CRE_13990	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (444 aa)
	Cre-gsk-3	CRE-GSK-3 protein; Belongs to the protein kinase superfamily. (362 aa)
	CRE_17260	Protein kinase domain-containing protein. (347 aa)
	CRE_15384	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (367 aa)
	Cre-apr-1	CRE-APR-1 protein. (1093 aa)
	Cre-pop-1	CRE-POP-1 protein. (442 aa)
	CRE_24760	Uncharacterized protein. (93 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_11693	CRE_15384	E3M456	E3MC24	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.925
CRE_11693	Cre-apr-1	E3M456	E3MWZ4	Protein kinase domain-containing protein.	CRE-APR-1 protein.	0.899
CRE_11693	Cre-axl-1	E3M456	E3LV80	Protein kinase domain-containing protein.	CRE-AXL-1 protein.	0.829
CRE_11693	Cre-bar-1	E3M456	E3LD44	Protein kinase domain-containing protein.	CRE-BAR-1 protein.	0.965
CRE_11693	Cre-kin-19	E3M456	E3M8C8	Protein kinase domain-containing protein.	CRE-KIN-19 protein; Belongs to the protein kinase superfamily.	0.820
CRE_11693	Cre-lin-23	E3M456	E3LR63	Protein kinase domain-containing protein.	CRE-LIN-23 protein.	0.876
CRE_11693	Cre-lit-1	E3M456	E3LYG8	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.695
CRE_11693	Cre-pry-1	E3M456	E3LN06	Protein kinase domain-containing protein.	CRE-PRY-1 protein.	0.944
CRE_11693	Cre-sys-1	E3M456	E3M372	Protein kinase domain-containing protein.	CRE-SYS-1 protein.	0.823
CRE_11693	Cre-wrm-1	E3M456	E3LYX1	Protein kinase domain-containing protein.	CRE-WRM-1 protein.	0.965
CRE_13990	CRE_15384	E3M8P0	E3MC24	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.899
CRE_13990	CRE_17260	E3M8P0	E3MAE3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.698
CRE_13990	Cre-apr-1	E3M8P0	E3MWZ4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CRE-APR-1 protein.	0.968
CRE_13990	Cre-axl-1	E3M8P0	E3LV80	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CRE-AXL-1 protein.	0.841
CRE_13990	Cre-bar-1	E3M8P0	E3LD44	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CRE-BAR-1 protein.	0.991
CRE_13990	Cre-kin-19	E3M8P0	E3M8C8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CRE-KIN-19 protein; Belongs to the protein kinase superfamily.	0.895
CRE_13990	Cre-lin-23	E3M8P0	E3LR63	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CRE-LIN-23 protein.	0.932
CRE_13990	Cre-lit-1	E3M8P0	E3LYG8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.695
CRE_13990	Cre-pry-1	E3M8P0	E3LN06	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CRE-PRY-1 protein.	0.971
CRE_13990	Cre-sys-1	E3M8P0	E3M372	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CRE-SYS-1 protein.	0.826