(5 nodes) G-protein activation, and Muscarinic acetylcholine receptors network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cre-gar-2	CRE-GAR-2 protein; Belongs to the G-protein coupled receptor 1 family. (689 aa)
	Cre-egl-30	CRE-EGL-30 protein. (355 aa)
	Cre-gar-3	CRE-GAR-3 protein; Belongs to the G-protein coupled receptor 1 family. (629 aa)
	Cre-gpc-1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (63 aa)
	Cre-gpb-2	CRE-GPB-2 protein. (369 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cre-egl-30	Cre-gar-2	E3LXV8	E3LWU3	CRE-EGL-30 protein.	CRE-GAR-2 protein; Belongs to the G-protein coupled receptor 1 family.	0.963
Cre-egl-30	Cre-gar-3	E3LXV8	E3MNE3	CRE-EGL-30 protein.	CRE-GAR-3 protein; Belongs to the G-protein coupled receptor 1 family.	0.981
Cre-egl-30	Cre-gpb-2	E3LXV8	E3N469	CRE-EGL-30 protein.	CRE-GPB-2 protein.	0.996
Cre-egl-30	Cre-gpc-1	E3LXV8	E3MVK7	CRE-EGL-30 protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.991
Cre-gar-2	Cre-egl-30	E3LWU3	E3LXV8	CRE-GAR-2 protein; Belongs to the G-protein coupled receptor 1 family.	CRE-EGL-30 protein.	0.963
Cre-gar-2	Cre-gar-3	E3LWU3	E3MNE3	CRE-GAR-2 protein; Belongs to the G-protein coupled receptor 1 family.	CRE-GAR-3 protein; Belongs to the G-protein coupled receptor 1 family.	0.945
Cre-gar-2	Cre-gpb-2	E3LWU3	E3N469	CRE-GAR-2 protein; Belongs to the G-protein coupled receptor 1 family.	CRE-GPB-2 protein.	0.795
Cre-gar-2	Cre-gpc-1	E3LWU3	E3MVK7	CRE-GAR-2 protein; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.787
Cre-gar-3	Cre-egl-30	E3MNE3	E3LXV8	CRE-GAR-3 protein; Belongs to the G-protein coupled receptor 1 family.	CRE-EGL-30 protein.	0.981
Cre-gar-3	Cre-gar-2	E3MNE3	E3LWU3	CRE-GAR-3 protein; Belongs to the G-protein coupled receptor 1 family.	CRE-GAR-2 protein; Belongs to the G-protein coupled receptor 1 family.	0.945
Cre-gar-3	Cre-gpb-2	E3MNE3	E3N469	CRE-GAR-3 protein; Belongs to the G-protein coupled receptor 1 family.	CRE-GPB-2 protein.	0.955
Cre-gar-3	Cre-gpc-1	E3MNE3	E3MVK7	CRE-GAR-3 protein; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.920
Cre-gpb-2	Cre-egl-30	E3N469	E3LXV8	CRE-GPB-2 protein.	CRE-EGL-30 protein.	0.996
Cre-gpb-2	Cre-gar-2	E3N469	E3LWU3	CRE-GPB-2 protein.	CRE-GAR-2 protein; Belongs to the G-protein coupled receptor 1 family.	0.795
Cre-gpb-2	Cre-gar-3	E3N469	E3MNE3	CRE-GPB-2 protein.	CRE-GAR-3 protein; Belongs to the G-protein coupled receptor 1 family.	0.955
Cre-gpb-2	Cre-gpc-1	E3N469	E3MVK7	CRE-GPB-2 protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.995
Cre-gpc-1	Cre-egl-30	E3MVK7	E3LXV8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	CRE-EGL-30 protein.	0.991
Cre-gpc-1	Cre-gar-2	E3MVK7	E3LWU3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	CRE-GAR-2 protein; Belongs to the G-protein coupled receptor 1 family.	0.787
Cre-gpc-1	Cre-gar-3	E3MVK7	E3MNE3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	CRE-GAR-3 protein; Belongs to the G-protein coupled receptor 1 family.	0.920
Cre-gpc-1	Cre-gpb-2	E3MVK7	E3N469	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	CRE-GPB-2 protein.	0.995