(29 nodes) Plasma lipoprotein remodeling, and Low-density lipoprotein (LDL) receptor class A, conserved site network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cre-vit-5	CRE-VIT-5 protein. (1599 aa)
	CRE_00508	VWFD domain-containing protein. (758 aa)
	CRE_00509	Vitellogenin domain-containing protein. (763 aa)
	CRE_00950	Vitellogenin domain-containing protein. (370 aa)
	CRE_00475	Vitellogenin domain-containing protein. (480 aa)
	Cre-vit-2	CRE-VIT-2 protein. (1620 aa)
	CRE_00388	Uncharacterized protein. (1613 aa)
	CRE_00880	DUF1943 domain-containing protein. (151 aa)
	CRE_00882	DUF1943 domain-containing protein. (409 aa)
	CRE_00395	Uncharacterized protein. (1596 aa)
	Cre-agr-1	CRE-AGR-1 protein. (1376 aa)
	CRE_26246	Uncharacterized protein. (793 aa)
	CRE_29515	Thioredoxin domain-containing protein. (420 aa)
	egg-1	LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial (By similarity). Seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane (By similarity). Appears to recruit or maintain together [...] (551 aa)
	Cre-pqn-25	CRE-PQN-25 protein. (787 aa)
	CRE_10167	Thioredoxin domain-containing protein. (409 aa)
	Cre-vit-6	CRE-VIT-6 protein. (1634 aa)
	CRE_20705	Uncharacterized protein. (702 aa)
	Cre-lrp-2	CRE-LRP-2 protein. (4864 aa)
	CRE_24983	Uncharacterized protein. (431 aa)
	CRE_24984	I-set domain-containing protein. (417 aa)
	CRE_25736	Uncharacterized protein. (221 aa)
	CRE_25672	Uncharacterized protein. (751 aa)
	CRE_29910	Uncharacterized protein. (273 aa)
	Cre-scav-6	CRE-SCAV-6 protein; Belongs to the CD36 family. (210 aa)
	Cre-dsc-4	CRE-DSC-4 protein. (891 aa)
	Cre-lrp-1	CRE-LRP-1 protein. (4438 aa)
	Cre-ost-1	CRE-OST-1 protein. (264 aa)
	CRE_14304	Homeobox domain-containing protein. (663 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_00388	CRE_10167	E3LEV7	E3M6M9	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.566
CRE_00388	CRE_14304	E3LEV7	E3NEY0	Uncharacterized protein.	Homeobox domain-containing protein.	0.660
CRE_00388	CRE_20705	E3LEV7	E3MFH4	Uncharacterized protein.	Uncharacterized protein.	0.641
CRE_00388	CRE_24983	E3LEV7	E3MHR5	Uncharacterized protein.	Uncharacterized protein.	0.536
CRE_00388	CRE_24984	E3LEV7	E3MHR7	Uncharacterized protein.	I-set domain-containing protein.	0.536
CRE_00388	CRE_25672	E3LEV7	E3MLD6	Uncharacterized protein.	Uncharacterized protein.	0.665
CRE_00388	CRE_25736	E3LEV7	E3MLC8	Uncharacterized protein.	Uncharacterized protein.	0.665
CRE_00388	CRE_26246	E3LEV7	E3LQZ1	Uncharacterized protein.	Uncharacterized protein.	0.536
CRE_00388	CRE_29515	E3LEV7	E3LVG0	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.566
CRE_00388	Cre-agr-1	E3LEV7	E3LQU9	Uncharacterized protein.	CRE-AGR-1 protein.	0.536
CRE_00388	Cre-dsc-4	E3LEV7	E3N5T2	Uncharacterized protein.	CRE-DSC-4 protein.	0.887
CRE_00388	Cre-lrp-1	E3LEV7	E3NCL0	Uncharacterized protein.	CRE-LRP-1 protein.	0.652
CRE_00388	Cre-lrp-2	E3LEV7	E3MGD3	Uncharacterized protein.	CRE-LRP-2 protein.	0.652
CRE_00388	Cre-ost-1	E3LEV7	E3NES9	Uncharacterized protein.	CRE-OST-1 protein.	0.663
CRE_00388	Cre-pqn-25	E3LEV7	E3LZ23	Uncharacterized protein.	CRE-PQN-25 protein.	0.463
CRE_00388	Cre-scav-6	E3LEV7	E3N438	Uncharacterized protein.	CRE-SCAV-6 protein; Belongs to the CD36 family.	0.656
CRE_00388	Cre-vit-6	E3LEV7	E3M6R6	Uncharacterized protein.	CRE-VIT-6 protein.	0.527
CRE_00388	egg-1	E3LEV7	E3LYX0	Uncharacterized protein.	LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial (By similarity). Seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane (By similarity). Appears to recruit or maintain together [...]	0.665
CRE_00395	CRE_10167	E3LEW7	E3M6M9	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.566
CRE_00395	CRE_14304	E3LEW7	E3NEY0	Uncharacterized protein.	Homeobox domain-containing protein.	0.660