(21 nodes) Mixed, incl. Notch receptor processing, and Termination of O-glycan biosynthesis network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRE_28234	Uncharacterized protein. (402 aa)
	Cre-spk-1	CRE-SPK-1 protein. (1153 aa)
	Cre-aph-2	CRE-APH-2 protein. (722 aa)
	Cre-sel-12	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (383 aa)
	Cre-dsl-4	CRE-DSL-4 protein. (444 aa)
	Cre-num-1	CRE-NUM-1 protein. (406 aa)
	Cre-aph-1	CRE-APH-1 protein. (314 aa)
	Cre-hop-1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (355 aa)
	CRE_00992	Uncharacterized protein. (901 aa)
	Cre-pen-2	CRE-PEN-2 protein. (101 aa)
	CRE_13515	Uncharacterized protein. (1168 aa)
	Cre-lag-1	CRE-LAG-1 protein. (686 aa)
	CRE_04235	Uncharacterized protein. (390 aa)
	Cre-spe-4	CRE-SPE-4 protein. (464 aa)
	CRE_27801	Uncharacterized protein. (1349 aa)
	CRE_01348	Anaphylatoxin-like domain-containing protein. (184 aa)
	CRE_01350	Uncharacterized protein. (74 aa)
	Cre-glp-1	CRE-GLP-1 protein. (1308 aa)
	Cre-lin-12	CRE-LIN-12 protein. (1083 aa)
	CRE_27979	Uncharacterized protein. (487 aa)
	CRE_23858	Uncharacterized protein. (82 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_00992	CRE_01348	E3MI48	E3ND97	Uncharacterized protein.	Anaphylatoxin-like domain-containing protein.	0.724
CRE_00992	CRE_01350	E3MI48	E3ND99	Uncharacterized protein.	Uncharacterized protein.	0.724
CRE_00992	CRE_23858	E3MI48	E3NVH0	Uncharacterized protein.	Uncharacterized protein.	0.761
CRE_00992	CRE_27979	E3MI48	E3NSN3	Uncharacterized protein.	Uncharacterized protein.	0.860
CRE_00992	Cre-aph-1	E3MI48	E3MFH0	Uncharacterized protein.	CRE-APH-1 protein.	0.785
CRE_00992	Cre-aph-2	E3MI48	E3LUW2	Uncharacterized protein.	CRE-APH-2 protein.	0.859
CRE_00992	Cre-dsl-4	E3MI48	E3ME98	Uncharacterized protein.	CRE-DSL-4 protein.	0.724
CRE_00992	Cre-glp-1	E3MI48	E3NFX9	Uncharacterized protein.	CRE-GLP-1 protein.	0.724
CRE_00992	Cre-hop-1	E3MI48	E3MGI1	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.761
CRE_00992	Cre-lag-1	E3MI48	E3MSD2	Uncharacterized protein.	CRE-LAG-1 protein.	0.860
CRE_00992	Cre-lin-12	E3MI48	E3NFY7	Uncharacterized protein.	CRE-LIN-12 protein.	0.724
CRE_00992	Cre-num-1	E3MI48	E3MEZ1	Uncharacterized protein.	CRE-NUM-1 protein.	0.762
CRE_00992	Cre-pen-2	E3MI48	E3MI78	Uncharacterized protein.	CRE-PEN-2 protein.	0.810
CRE_00992	Cre-sel-12	E3MI48	E3MA46	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.761
CRE_01348	CRE_00992	E3ND97	E3MI48	Anaphylatoxin-like domain-containing protein.	Uncharacterized protein.	0.724
CRE_01348	CRE_04235	E3ND97	E3MYW0	Anaphylatoxin-like domain-containing protein.	Uncharacterized protein.	0.724
CRE_01348	CRE_13515	E3ND97	E3MR27	Anaphylatoxin-like domain-containing protein.	Uncharacterized protein.	0.724
CRE_01348	CRE_23858	E3ND97	E3NVH0	Anaphylatoxin-like domain-containing protein.	Uncharacterized protein.	0.639
CRE_01348	CRE_27801	E3ND97	E3N5J9	Anaphylatoxin-like domain-containing protein.	Uncharacterized protein.	0.436
CRE_01348	CRE_27979	E3ND97	E3NSN3	Anaphylatoxin-like domain-containing protein.	Uncharacterized protein.	0.861