(16 nodes) Receptor tyrosine kinase binding network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cre-lin-17	CRE-LIN-17 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
	CRE_03756	Uncharacterized protein. (642 aa)
	Cre-mom-2	CRE-MOM-2 protein. (366 aa)
	Cre-dsh-1	CRE-DSH-1 protein. (934 aa)
	Cre-sli-1	CRE-SLI-1 protein. (537 aa)
	CRE_17846	IRS-type PTB domain-containing protein. (532 aa)
	Cre-num-1	CRE-NUM-1 protein. (406 aa)
	Cre-shc-1	CRE-SHC-1 protein. (323 aa)
	Cre-egl-20	CRE-EGL-20 protein. (393 aa)
	Cre-ced-2	CRE-CED-2 protein. (294 aa)
	CRE_31543	Uncharacterized protein. (87 aa)
	CRE_03755	Uncharacterized protein. (351 aa)
	Cre-nck-1	CRE-NCK-1 protein. (392 aa)
	Cre-cwn-1	CRE-CWN-1 protein. (406 aa)
	Cre-mlk-1	CRE-MLK-1 protein. (1049 aa)
	CRE_16580	Uncharacterized protein. (193 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_03755	CRE_17846	E3LY36	E3MDN2	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.599
CRE_03755	Cre-ced-2	E3LY36	E3N5V4	Uncharacterized protein.	CRE-CED-2 protein.	0.743
CRE_03755	Cre-nck-1	E3LY36	E3LEM6	Uncharacterized protein.	CRE-NCK-1 protein.	0.481
CRE_03755	Cre-shc-1	E3LY36	E3MFM3	Uncharacterized protein.	CRE-SHC-1 protein.	0.537
CRE_03755	Cre-sli-1	E3LY36	E3MA78	Uncharacterized protein.	CRE-SLI-1 protein.	0.674
CRE_03756	CRE_17846	E3LY37	E3MDN2	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.599
CRE_03756	Cre-ced-2	E3LY37	E3N5V4	Uncharacterized protein.	CRE-CED-2 protein.	0.743
CRE_03756	Cre-nck-1	E3LY37	E3LEM6	Uncharacterized protein.	CRE-NCK-1 protein.	0.481
CRE_03756	Cre-sli-1	E3LY37	E3MA78	Uncharacterized protein.	CRE-SLI-1 protein.	0.674
CRE_16580	CRE_31543	E3NUH1	E3NI49	Uncharacterized protein.	Uncharacterized protein.	0.887
CRE_16580	Cre-cwn-1	E3NUH1	E3NMD3	Uncharacterized protein.	CRE-CWN-1 protein.	0.892
CRE_16580	Cre-dsh-1	E3NUH1	E3M4H5	Uncharacterized protein.	CRE-DSH-1 protein.	0.916
CRE_16580	Cre-lin-17	E3NUH1	E3LM68	Uncharacterized protein.	CRE-LIN-17 protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.996
CRE_16580	Cre-mom-2	E3NUH1	E3LZQ8	Uncharacterized protein.	CRE-MOM-2 protein.	0.913
CRE_17846	CRE_03755	E3MDN2	E3LY36	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.599
CRE_17846	CRE_03756	E3MDN2	E3LY37	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.599
CRE_17846	Cre-ced-2	E3MDN2	E3N5V4	IRS-type PTB domain-containing protein.	CRE-CED-2 protein.	0.975
CRE_17846	Cre-mlk-1	E3MDN2	E3LP05	IRS-type PTB domain-containing protein.	CRE-MLK-1 protein.	0.664
CRE_17846	Cre-nck-1	E3MDN2	E3LEM6	IRS-type PTB domain-containing protein.	CRE-NCK-1 protein.	0.504
CRE_17846	Cre-shc-1	E3MDN2	E3MFM3	IRS-type PTB domain-containing protein.	CRE-SHC-1 protein.	0.502