(53 nodes) Negative regulation of locomotion network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRE_27097	Uncharacterized protein. (822 aa)
	Cre-pde-4	Phosphodiesterase. (734 aa)
	Cre-dat-1	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (615 aa)
	CRE_30674	Uncharacterized protein. (291 aa)
	Cre-blmp-1	CRE-BLMP-1 protein. (816 aa)
	Cre-unc-40	CRE-UNC-40 protein. (1432 aa)
	Cre-mab-20	CRE-MAB-20 protein; Belongs to the semaphorin family. (659 aa)
	Cre-pdr-1	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (387 aa)
	Cre-swan-1	CRE-SWAN-1 protein. (381 aa)
	Cre-abl-1	Tyrosine-protein kinase. (1287 aa)
	CRE_00132	Uncharacterized protein. (358 aa)
	Cre-gei-15	CRE-GEI-15 protein. (414 aa)
	Cre-vab-3	CRE-VAB-3 protein. (462 aa)
	Cre-flp-7	CRE-FLP-7 protein. (179 aa)
	Cre-sym-3	CRE-SYM-3 protein. (305 aa)
	Cre-gpb-1	CRE-GPB-1 protein. (340 aa)
	CRE_02039	Uncharacterized protein. (1259 aa)
	CRE_08658	Uncharacterized protein. (407 aa)
	CRE_08659	Uncharacterized protein. (400 aa)
	CRE_08660	Uncharacterized protein. (308 aa)
	CRE_08661	Uncharacterized protein. (393 aa)
	Cre-vab-8	CRE-VAB-8 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1063 aa)
	CRE_15262	G_PROTEIN_RECEP_F1_2 domain-containing protein. (125 aa)
	CRE_16580	Uncharacterized protein. (193 aa)
	CRE_16572	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (435 aa)
	CRE_21057	Uncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	Cre-nol-1	CRE-NOL-1 protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (677 aa)
	CRE_17644	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (113 aa)
	CRE_16480	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	CRE_16478	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (424 aa)
	CRE_30190	Uncharacterized protein. (827 aa)
	CRE_24211	Uncharacterized protein. (333 aa)
	Cre-rap-2	CRE-RAP-2 protein. (181 aa)
	CRE_03357	Homeobox domain-containing protein. (167 aa)
	Cre-unc-32	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (895 aa)
	Cre-stn-1	CRE-STN-1 protein. (455 aa)
	Cre-ahr-1	CRE-AHR-1 protein. (631 aa)
	CRE_04960	Uncharacterized protein. (307 aa)
	Cre-egl-20	CRE-EGL-20 protein. (393 aa)
	CRE_01044	Dimer_Tnp_hAT domain-containing protein. (1028 aa)
	Cre-smp-2	CRE-SMP-2 protein; Belongs to the semaphorin family. (657 aa)
	CRE_24414	Uncharacterized protein. (91 aa)
	Cre-smp-1	CRE-SMP-1 protein; Belongs to the semaphorin family. (711 aa)
	Cre-dop-2	CRE-DOP-2 protein; Belongs to the G-protein coupled receptor 1 family. (846 aa)
	CRE_15303	Uncharacterized protein. (574 aa)
	Cre-slt-1	CRE-SLT-1 protein. (857 aa)
	Cre-dgk-1	Diacylglycerol kinase. (913 aa)
	CRE_17086	Phorbol-ester/DAG-type domain-containing protein. (55 aa)
	Cre-srgp-1	CRE-SRGP-1 protein. (1059 aa)
	CRE_12808	Rho-GAP domain-containing protein; Belongs to the glycosyltransferase 47 family. (847 aa)
	Cre-rap-3	CRE-RAP-3 protein. (259 aa)
	Cre-rig-6	CRE-RIG-6 protein. (1216 aa)
	Cre-eat-16	CRE-EAT-16 protein. (477 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_00132	CRE_15303	E3LDB1	E3MC36	Uncharacterized protein.	Uncharacterized protein.	0.636
CRE_00132	Cre-abl-1	E3LDB1	E3M213	Uncharacterized protein.	Tyrosine-protein kinase.	0.656
CRE_00132	Cre-gpb-1	E3LDB1	E3LFW0	Uncharacterized protein.	CRE-GPB-1 protein.	0.542
CRE_00132	Cre-rig-6	E3LDB1	E3M476	Uncharacterized protein.	CRE-RIG-6 protein.	0.573
CRE_00132	Cre-slt-1	E3LDB1	E3MC35	Uncharacterized protein.	CRE-SLT-1 protein.	0.636
CRE_04960	Cre-mab-20	E3MN65	E3LXX6	Uncharacterized protein.	CRE-MAB-20 protein; Belongs to the semaphorin family.	0.684
CRE_04960	Cre-rig-6	E3MN65	E3M476	Uncharacterized protein.	CRE-RIG-6 protein.	0.471
CRE_04960	Cre-smp-1	E3MN65	E3MFE0	Uncharacterized protein.	CRE-SMP-1 protein; Belongs to the semaphorin family.	0.684
CRE_04960	Cre-smp-2	E3MN65	E3MGB5	Uncharacterized protein.	CRE-SMP-2 protein; Belongs to the semaphorin family.	0.684
CRE_12808	Cre-abl-1	E3M7Z5	E3M213	Rho-GAP domain-containing protein; Belongs to the glycosyltransferase 47 family.	Tyrosine-protein kinase.	0.732
CRE_12808	Cre-rap-2	E3M7Z5	E3NCJ0	Rho-GAP domain-containing protein; Belongs to the glycosyltransferase 47 family.	CRE-RAP-2 protein.	0.569
CRE_12808	Cre-rap-3	E3M7Z5	E3M7R0	Rho-GAP domain-containing protein; Belongs to the glycosyltransferase 47 family.	CRE-RAP-3 protein.	0.569
CRE_12808	Cre-swan-1	E3M7Z5	E3M0E9	Rho-GAP domain-containing protein; Belongs to the glycosyltransferase 47 family.	CRE-SWAN-1 protein.	0.528
CRE_15262	Cre-gpb-1	E3NWW7	E3LFW0	G_PROTEIN_RECEP_F1_2 domain-containing protein.	CRE-GPB-1 protein.	0.795
CRE_15303	CRE_00132	E3MC36	E3LDB1	Uncharacterized protein.	Uncharacterized protein.	0.636
CRE_15303	Cre-abl-1	E3MC36	E3M213	Uncharacterized protein.	Tyrosine-protein kinase.	0.861
CRE_15303	Cre-gei-15	E3MC36	E3LDB2	Uncharacterized protein.	CRE-GEI-15 protein.	0.636
CRE_15303	Cre-slt-1	E3MC36	E3MC35	Uncharacterized protein.	CRE-SLT-1 protein.	0.921
CRE_15303	Cre-unc-40	E3MC36	E3LXC8	Uncharacterized protein.	CRE-UNC-40 protein.	0.913
CRE_15303	Cre-vab-8	E3MC36	E3LQ23	Uncharacterized protein.	CRE-VAB-8 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.449