(100 nodes) Striated muscle dense body network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRE_30581	Uncharacterized protein. (254 aa)
	CRE_15085	Uncharacterized protein. (379 aa)
	CRE_02702	NAD(P)-bd_dom domain-containing protein. (167 aa)
	Cre-exl-1	CRE-EXL-1 protein. (239 aa)
	Cre-pat-6	CRE-PAT-6 protein. (376 aa)
	Cre-smg-8	CRE-SMG-8 protein. (892 aa)
	CRE_30431	Ig-like domain-containing protein. (197 aa)
	CRE_16353	Uncharacterized protein. (279 aa)
	CRE_16337	Uncharacterized protein. (143 aa)
	CRE_16388	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (271 aa)
	Cre-slo-1	CRE-SLO-1 protein. (1167 aa)
	Cre-har-1	CRE-HAR-1 protein. (158 aa)
	CRE_06011	DUF727 domain-containing protein. (246 aa)
	Cre-bre-1	CRE-BRE-1 protein. (399 aa)
	CRE_15599	Uncharacterized protein. (231 aa)
	Cre-unc-23	CRE-UNC-23 protein. (450 aa)
	CRE_12211	Arrestin_C domain-containing protein. (343 aa)
	Cre-pat-2	CRE-PAT-2 protein; Belongs to the integrin alpha chain family. (1225 aa)
	Cre-dys-1	CRE-DYS-1 protein. (3571 aa)
	Cre-alp-1	CRE-ALP-1 protein. (1271 aa)
	Cre-rnf-5	CRE-RNF-5 protein. (278 aa)
	Cre-cpna-1	CRE-CPNA-1 protein. (689 aa)
	CRE_20436	Uncharacterized protein. (326 aa)
	CRE_16236	Uncharacterized protein. (661 aa)
	Cre-pat-4	CRE-PAT-4 protein. (352 aa)
	CRE_16919	Uncharacterized protein. (250 aa)
	Cre-cnb-1	CRE-CNB-1 protein. (171 aa)
	CRE_11261	Uncharacterized protein. (504 aa)
	Cre-aldo-1	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (365 aa)
	Cre-unc-112	CRE-UNC-112 protein. (720 aa)
	CRE_03213	Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (360 aa)
	Cre-sup-10	CRE-SUP-10 protein. (378 aa)
	Cre-cutc-1	CRE-CUTC-1 protein. (269 aa)
	CRE_01043	Uncharacterized protein. (332 aa)
	CRE_24983	Uncharacterized protein. (431 aa)
	Cre-unc-52	CRE-UNC-52 protein. (3425 aa)
	Cre-eva-1	CRE-EVA-1 protein. (473 aa)
	Cre-unc-95	CRE-UNC-95 protein. (373 aa)
	Cre-dyc-1	CRE-DYC-1 protein. (896 aa)
	Cre-madd-2	CRE-MADD-2 protein. (748 aa)
	CRE_16672	Uncharacterized protein. (280 aa)
	Cre-pfn-3	Profilin; Belongs to the profilin family. (126 aa)
	Cre-tag-303	CRE-TAG-303 protein. (299 aa)
	CRE_14027	Uncharacterized protein. (342 aa)
	Cre-pat-3	Integrin beta; Belongs to the integrin beta chain family. (829 aa)
	CRE_12537	Pyruvate kinase; Belongs to the pyruvate kinase family. (515 aa)
	CRE_12680	PH domain-containing protein; Belongs to the actin family. (552 aa)
	Cre-deb-1	CRE-DEB-1 protein. (1010 aa)
	CRE_10871	Uncharacterized protein. (379 aa)
	CRE_11905	Uncharacterized protein. (459 aa)
	CRE_07230	Uncharacterized protein. (498 aa)
	Cre-pkn-1	CRE-PKN-1 protein. (1127 aa)
	CRE_07359	Uncharacterized protein. (545 aa)
	CRE_07411	PlsC domain-containing protein. (370 aa)
	Cre-sup-9	Two pore potassium channel protein sup-9. (394 aa)
	Cre-pxl-1	CRE-PXL-1 protein. (416 aa)
	Cre-mlp-1	CRE-MLP-1 protein. (182 aa)
	CRE_04860	TPR_REGION domain-containing protein. (242 aa)
	CRE_04853	UTP--glucose-1-phosphate uridylyltransferase. (511 aa)
	CRE_04629	Uncharacterized protein. (116 aa)
	CRE_03799	Uncharacterized protein. (423 aa)
	CRE_03910	Uncharacterized protein. (2551 aa)
	CRE_03860	Uncharacterized protein. (169 aa)
	CRE_03640	SH2 domain-containing protein. (425 aa)
	Cre-arx-5	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (183 aa)
	Cre-frg-1	CRE-FRG-1 protein. (275 aa)
	CRE_29827	MPN domain-containing protein. (196 aa)
	CRE_29820	Methyltranfer_dom domain-containing protein. (506 aa)
	Cre-hsp-12.1	CRE-HSP-12.1 protein; Belongs to the small heat shock protein (HSP20) family. (109 aa)
	Cre-set-18	CRE-SET-18 protein. (507 aa)
	Cre-rsbp-1	CRE-RSBP-1 protein. (187 aa)
	Cre-hgo-1	CRE-HGO-1 protein. (437 aa)
	Cre-uig-1	CRE-UIG-1 protein. (906 aa)
	Cre-unc-93	CRE-UNC-93 protein. (682 aa)
	CRE_25594	Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (162 aa)
	CRE_25203	AIP3 domain-containing protein. (866 aa)
	CRE_26075	Uncharacterized protein. (389 aa)
	CRE_26302	CN hydrolase domain-containing protein. (456 aa)
	Cre-spon-1	CRE-SPON-1 protein. (831 aa)
	Cre-unc-70	Spectrin beta chain; Belongs to the spectrin family. (2342 aa)
	Cre-atn-1	CRE-ATN-1 protein. (921 aa)
	CRE_28065	Uncharacterized protein. (208 aa)
	Cre-ctn-1	CRE-CTN-1 protein. (642 aa)
	CRE_18668	Uncharacterized protein. (348 aa)
	CRE_18834	Uncharacterized protein. (466 aa)
	CRE_18461	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (193 aa)
	CRE_23857	Pyruvate kinase; Belongs to the pyruvate kinase family. (202 aa)
	Cre-ltd-1	CRE-LTD-1 protein. (723 aa)
	CRE_01961	Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (186 aa)
	Cre-zyx-1	CRE-ZYX-1 protein. (648 aa)
	Cre-gyg-1	CRE-GYG-1 protein. (431 aa)
	Cre-unc-97	LIM domain-containing protein. (353 aa)
	Cre-hsp-25	CRE-HSP-25 protein; Belongs to the small heat shock protein (HSP20) family. (208 aa)
	Cre-sgca-1	CRE-SGCA-1 protein. (467 aa)
	Cre-gei-15	CRE-GEI-15 protein. (414 aa)
	CRE_00132	Uncharacterized protein. (358 aa)
	CRE_08852	Uncharacterized protein. (329 aa)
	CRE_23856	PK domain-containing protein. (212 aa)
	CRE_22746	Uncharacterized protein. (272 aa)
	CRE_29283	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (271 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_00132	CRE_30431	E3LDB1	E3NDW4	Uncharacterized protein.	Ig-like domain-containing protein.	0.656
CRE_00132	Cre-deb-1	E3LDB1	E3M727	Uncharacterized protein.	CRE-DEB-1 protein.	0.414
CRE_00132	Cre-pat-2	E3LDB1	E3N043	Uncharacterized protein.	CRE-PAT-2 protein; Belongs to the integrin alpha chain family.	0.676
CRE_00132	Cre-pat-3	E3LDB1	E3M8G5	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.642
CRE_01043	Cre-atn-1	E3MI10	E3LNI9	Uncharacterized protein.	CRE-ATN-1 protein.	0.788
CRE_01043	Cre-cnb-1	E3MI10	E3MQD1	Uncharacterized protein.	CRE-CNB-1 protein.	0.551
CRE_01043	Cre-dys-1	E3MI10	E3MYR8	Uncharacterized protein.	CRE-DYS-1 protein.	0.800
CRE_01043	Cre-mlp-1	E3MI10	E3LYP7	Uncharacterized protein.	CRE-MLP-1 protein.	0.580
CRE_01043	Cre-zyx-1	E3MI10	E3LEZ7	Uncharacterized protein.	CRE-ZYX-1 protein.	0.657
CRE_02702	CRE_16388	E3NLE0	E3NC55	NAD(P)-bd_dom domain-containing protein.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.414
CRE_02702	CRE_29283	E3NLE0	E3NSA2	NAD(P)-bd_dom domain-containing protein.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.414
CRE_03213	CRE_15599	E3MMR1	E3N2P6	Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Uncharacterized protein.	0.419
CRE_03213	CRE_18461	E3MMR1	E3LKM5	Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.586
CRE_03213	CRE_26302	E3MMR1	E3LR86	Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	CN hydrolase domain-containing protein.	0.567
CRE_03640	CRE_10871	E3LXE6	E3M597	SH2 domain-containing protein.	Uncharacterized protein.	0.502
CRE_03640	CRE_15085	E3LXE6	E3NQ58	SH2 domain-containing protein.	Uncharacterized protein.	0.502
CRE_03640	Cre-pat-3	E3LXE6	E3M8G5	SH2 domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.975
CRE_03640	Cre-pat-4	E3LXE6	E3MSP7	SH2 domain-containing protein.	CRE-PAT-4 protein.	0.626
CRE_03910	CRE_12680	E3LXS8	E3M792	Uncharacterized protein.	PH domain-containing protein; Belongs to the actin family.	0.669
CRE_03910	CRE_28065	E3LXS8	E3LM47	Uncharacterized protein.	Uncharacterized protein.	0.969