(92 nodes) Cytoplasmic region network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRE_26876	Uncharacterized protein. (129 aa)
	CRE_21568	Uncharacterized protein. (172 aa)
	CRE_21567	Uncharacterized protein. (192 aa)
	CRE_20037	Uncharacterized protein. (1094 aa)
	CRE_20565	Uncharacterized protein. (402 aa)
	Cre-lis-1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. Belongs to the WD repeat LIS1/nudF family. (404 aa)
	CRE_22666	C2 domain-containing protein. (574 aa)
	Cre-unc-13	CRE-UNC-13 protein. (1573 aa)
	CRE_16385	Uncharacterized protein. (1167 aa)
	Cre-ifta-2	CRE-IFTA-2 protein. (232 aa)
	Cre-dylt-2	CRE-DYLT-2 protein. (123 aa)
	Cre-ifta-1	CRE-IFTA-1 protein. (1250 aa)
	Cre-elks-1	CRE-ELKS-1 protein. (868 aa)
	CRE_19394	Uncharacterized protein. (367 aa)
	CRE_12161	Uncharacterized protein. (246 aa)
	Cre-exc-5	CRE-EXC-5 protein. (829 aa)
	Cre-cls-1	CRE-CLS-1 protein. (1357 aa)
	CRE_24051	Uncharacterized protein. (1053 aa)
	CRE_21952	Uncharacterized protein. (615 aa)
	Cre-che-3	CRE-CHE-3 protein. (4175 aa)
	Cre-klp-20	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (752 aa)
	Cre-par-2	CRE-PAR-2 protein. (506 aa)
	CRE_16146	RING-type domain-containing protein. (192 aa)
	Cre-rab-28	CRE-RAB-28 protein. (267 aa)
	Cre-xbx-1	CRE-XBX-1 protein. (416 aa)
	CRE_04066	Uncharacterized protein. (658 aa)
	CRE_04106	Uncharacterized protein. (331 aa)
	CRE_04095	Doublecortin domain-containing protein. (451 aa)
	Cre-osm-1	CRE-OSM-1 protein. (1722 aa)
	CRE_19180	Uncharacterized protein. (1146 aa)
	CRE_09491	Uncharacterized protein. (416 aa)
	Cre-unc-116	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (839 aa)
	Cre-rab-8	CRE-RAB-8 protein. (211 aa)
	Cre-dhc-1	CRE-DHC-1 protein. (4583 aa)
	Cre-osm-12	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (736 aa)
	Cre-bbs-1	CRE-BBS-1 protein. (596 aa)
	Cre-arl-6	CRE-ARL-6 protein. (190 aa)
	CRE_15437	Uncharacterized protein. (739 aa)
	Cre-tbb-4	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
	CRE_16608	Uncharacterized protein. (316 aa)
	Cre-dyf-11	CRE-DYF-11 protein. (551 aa)
	CRE_13282	Uncharacterized protein. (247 aa)
	Cre-tir-1	CRE-TIR-1 protein. (943 aa)
	CRE_13426	Uncharacterized protein. (181 aa)
	Cre-pod-1	CRE-POD-1 protein. (1165 aa)
	CRE_12526	Uncharacterized protein. (407 aa)
	CRE_12481	Uncharacterized protein. (512 aa)
	CRE_12477	Uncharacterized protein. (70 aa)
	Cre-dli-1	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (441 aa)
	CRE_10999	Uncharacterized protein. (497 aa)
	Cre-osm-3	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (702 aa)
	CRE_10812	Uncharacterized protein; Belongs to the actin family. (482 aa)
	Cre-nsy-1	CRE-NSY-1 protein. (1506 aa)
	CRE_07210	Uncharacterized protein. (446 aa)
	CRE_07561	Uncharacterized protein. (681 aa)
	CRE_07239	Uncharacterized protein. (435 aa)
	Cre-syd-2	CRE-SYD-2 protein. (1180 aa)
	Cre-apd-3	AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (1235 aa)
	Cre-bbs-5	CRE-BBS-5 protein. (382 aa)
	CRE_04562	Uncharacterized protein. (199 aa)
	CRE_04734	Par3_HAL_N_term domain-containing protein. (114 aa)
	Cre-par-3	CRE-PAR-3 protein. (1301 aa)
	Cre-tba-5	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (468 aa)
	Cre-let-767	CRE-LET-767 protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (328 aa)
	CRE_02911	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (711 aa)
	Cre-che-13	CRE-CHE-13 protein. (308 aa)
	CRE_30761	Uncharacterized protein. (3291 aa)
	Cre-cls-3	CRE-CLS-3 protein. (992 aa)
	CRE_25510	Uncharacterized protein. (297 aa)
	Cre-cls-2	CRE-CLS-2 protein. (1058 aa)
	Cre-unc-104	CRE-UNC-104 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1633 aa)
	Cre-insc-1	CRE-INSC-1 protein. (649 aa)
	CRE_27368	Uncharacterized protein. (544 aa)
	Cre-che-11	CRE-CHE-11 protein. (922 aa)
	Cre-erm-1	CRE-ERM-1 protein. (562 aa)
	CRE_18840	ARL2_Bind_BART domain-containing protein. (96 aa)
	CRE_18839	Uncharacterized protein. (611 aa)
	Cre-clic-1	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
	Cre-unc-10	CRE-UNC-10 protein. (1593 aa)
	Cre-pqn-37	CRE-PQN-37 protein. (585 aa)
	Cre-klp-11	CRE-KLP-11 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (228 aa)
	Cre-kap-1	CRE-KAP-1 protein. (408 aa)
	Cre-dyf-1	CRE-DYF-1 protein. (655 aa)
	Cre-mtm-1	CRE-MTM-1 protein. (592 aa)
	CRE_20604	Adaptin_N domain-containing protein. (166 aa)
	CRE_24360	Uncharacterized protein. (145 aa)
	CRE_15231	Uncharacterized protein. (63 aa)
	CRE_16574	Uncharacterized protein. (405 aa)
	CRE_06253	Uncharacterized protein. (178 aa)
	CRE_05343	Uncharacterized protein; Belongs to the actin family. (304 aa)
	CRE_26006	Uncharacterized protein. (260 aa)
	CRE_11595	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (509 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_02911	Cre-arl-6	E3LWM6	E3MCR4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	CRE-ARL-6 protein.	0.581
CRE_02911	Cre-clic-1	E3LWM6	E3LKF0	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.699
CRE_02911	Cre-nsy-1	E3LWM6	E3M4C2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	CRE-NSY-1 protein.	0.652
CRE_04066	CRE_04095	E3MN45	E3MMW6	Uncharacterized protein.	Doublecortin domain-containing protein.	0.646
CRE_04066	CRE_09491	E3MN45	E3MJ51	Uncharacterized protein.	Uncharacterized protein.	0.872
CRE_04066	CRE_12477	E3MN45	E3M743	Uncharacterized protein.	Uncharacterized protein.	0.604
CRE_04066	CRE_12481	E3MN45	E3M748	Uncharacterized protein.	Uncharacterized protein.	0.604
CRE_04066	CRE_13426	E3MN45	E3M8A9	Uncharacterized protein.	Uncharacterized protein.	0.601
CRE_04066	CRE_15231	E3MN45	E3NUH2	Uncharacterized protein.	Uncharacterized protein.	0.604
CRE_04066	CRE_20565	E3MN45	E3NFD9	Uncharacterized protein.	Uncharacterized protein.	0.518
CRE_04066	CRE_27368	E3MN45	E3LQ05	Uncharacterized protein.	Uncharacterized protein.	0.772
CRE_04066	Cre-che-11	E3MN45	E3LQ03	Uncharacterized protein.	CRE-CHE-11 protein.	0.772
CRE_04066	Cre-che-13	E3MN45	E3LW12	Uncharacterized protein.	CRE-CHE-13 protein.	0.606
CRE_04066	Cre-dyf-1	E3MN45	E3NJ17	Uncharacterized protein.	CRE-DYF-1 protein.	0.616
CRE_04066	Cre-dyf-11	E3MN45	E3MA75	Uncharacterized protein.	CRE-DYF-11 protein.	0.621
CRE_04066	Cre-dylt-2	E3MN45	E3NAR3	Uncharacterized protein.	CRE-DYLT-2 protein.	0.658
CRE_04066	Cre-ifta-1	E3MN45	E3NAK2	Uncharacterized protein.	CRE-IFTA-1 protein.	0.872
CRE_04066	Cre-ifta-2	E3MN45	E3NBA9	Uncharacterized protein.	CRE-IFTA-2 protein.	0.622
CRE_04066	Cre-kap-1	E3MN45	E3NH28	Uncharacterized protein.	CRE-KAP-1 protein.	0.601
CRE_04066	Cre-osm-1	E3MN45	E3MKR1	Uncharacterized protein.	CRE-OSM-1 protein.	0.617