(21 nodes) Growth cone network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRE_00346	Uncharacterized protein. (672 aa)
	Cre-nmgp-1	CRE-NMGP-1 protein. (276 aa)
	Cre-mig-10	CRE-MIG-10 protein. (791 aa)
	Cre-sec-8	CRE-SEC-8 protein. (893 aa)
	Cre-unc-40	CRE-UNC-40 protein. (1432 aa)
	Cre-hum-7	CRE-HUM-7 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1887 aa)
	CRE_08188	BSD domain-containing protein. (365 aa)
	Cre-sel-12	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (383 aa)
	Cre-madd-2	CRE-MADD-2 protein. (748 aa)
	CRE_23954	DH domain-containing protein. (576 aa)
	CRE_23858	Uncharacterized protein. (82 aa)
	Cre-hop-1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (355 aa)
	Cre-rack-1	CRE-RACK-1 protein. (325 aa)
	Cre-unc-115	CRE-UNC-115 protein. (624 aa)
	Cre-unc-5	CRE-UNC-5 protein. (920 aa)
	Cre-let-92	Serine/threonine-protein phosphatase. (333 aa)
	Cre-spe-4	CRE-SPE-4 protein. (464 aa)
	CRE_25791	Uncharacterized protein. (131 aa)
	CRE_25792	Uncharacterized protein. (1378 aa)
	CRE_07953	Serine/threonine-protein phosphatase. (331 aa)
	CRE_30335	Death domain-containing protein. (373 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_23858	Cre-spe-4	E3NVH0	E3N426	Uncharacterized protein.	CRE-SPE-4 protein.	0.871
CRE_23954	Cre-hum-7	E3MG45	E3M3L8	DH domain-containing protein.	CRE-HUM-7 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.530
CRE_23954	Cre-unc-115	E3MG45	E3MMM7	DH domain-containing protein.	CRE-UNC-115 protein.	0.598
CRE_23954	Cre-unc-40	E3MG45	E3LXC8	DH domain-containing protein.	CRE-UNC-40 protein.	0.536
CRE_25791	CRE_30335	E3N5N5	E3NUY5	Uncharacterized protein.	Death domain-containing protein.	0.789
CRE_25791	Cre-hum-7	E3N5N5	E3M3L8	Uncharacterized protein.	CRE-HUM-7 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.698
CRE_25791	Cre-madd-2	E3N5N5	E3MBM3	Uncharacterized protein.	CRE-MADD-2 protein.	0.752
CRE_25791	Cre-unc-5	E3N5N5	E3MR05	Uncharacterized protein.	CRE-UNC-5 protein.	0.789
CRE_25792	CRE_30335	E3N5N6	E3NUY5	Uncharacterized protein.	Death domain-containing protein.	0.789
CRE_25792	Cre-hum-7	E3N5N6	E3M3L8	Uncharacterized protein.	CRE-HUM-7 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.698
CRE_25792	Cre-madd-2	E3N5N6	E3MBM3	Uncharacterized protein.	CRE-MADD-2 protein.	0.752
CRE_25792	Cre-unc-5	E3N5N6	E3MR05	Uncharacterized protein.	CRE-UNC-5 protein.	0.789
CRE_30335	CRE_25791	E3NUY5	E3N5N5	Death domain-containing protein.	Uncharacterized protein.	0.789
CRE_30335	CRE_25792	E3NUY5	E3N5N6	Death domain-containing protein.	Uncharacterized protein.	0.789
CRE_30335	Cre-madd-2	E3NUY5	E3MBM3	Death domain-containing protein.	CRE-MADD-2 protein.	0.559
CRE_30335	Cre-mig-10	E3NUY5	E3LT00	Death domain-containing protein.	CRE-MIG-10 protein.	0.551
CRE_30335	Cre-unc-115	E3NUY5	E3MMM7	Death domain-containing protein.	CRE-UNC-115 protein.	0.531
CRE_30335	Cre-unc-40	E3NUY5	E3LXC8	Death domain-containing protein.	CRE-UNC-40 protein.	0.981
Cre-hop-1	Cre-sel-12	E3MGI1	E3MA46	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.958
Cre-hop-1	Cre-spe-4	E3MGI1	E3N426	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	CRE-SPE-4 protein.	0.963