(22 nodes) Cortical actin cytoskeleton network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cre-unc-78	CRE-UNC-78 protein. (644 aa)
	Cre-spc-1	CRE-SPC-1 protein. (2370 aa)
	Cre-unc-70	Spectrin beta chain; Belongs to the spectrin family. (2342 aa)
	Cre-ani-2	CRE-ANI-2 protein. (1012 aa)
	CRE_25422	Uncharacterized protein. (2266 aa)
	Cre-unc-94	CRE-UNC-94 protein. (406 aa)
	Cre-pkc-3	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
	Cre-wsp-1	CRE-WSP-1 protein. (762 aa)
	CRE_10175	WH1 domain-containing protein. (179 aa)
	CRE_16652	PH domain-containing protein. (546 aa)
	Cre-aipl-1	CRE-AIPL-1 protein. (603 aa)
	Cre-ani-1	CRE-ANI-1 protein. (1167 aa)
	Cre-ani-3	CRE-ANI-3 protein. (751 aa)
	Cre-pfn-1	Profilin; Belongs to the profilin family. (132 aa)
	CRE_15735	PH domain-containing protein. (1723 aa)
	Cre-rho-1	CRE-RHO-1 protein. (192 aa)
	CRE_03486	Uncharacterized protein. (207 aa)
	CRE_15063	Uncharacterized protein. (184 aa)
	CRE_01476	CRIB domain-containing protein. (456 aa)
	CRE_01477	WH1 domain-containing protein. (179 aa)
	CRE_27967	Uncharacterized protein. (189 aa)
	CRE_27968	Uncharacterized protein. (514 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_01476	CRE_03486	E3NR52	E3NIA0	CRIB domain-containing protein.	Uncharacterized protein.	0.849
CRE_01476	CRE_15063	E3NR52	E3NMU6	CRIB domain-containing protein.	Uncharacterized protein.	0.849
CRE_01476	CRE_27967	E3NR52	E3NR64	CRIB domain-containing protein.	Uncharacterized protein.	0.824
CRE_01476	CRE_27968	E3NR52	E3NR65	CRIB domain-containing protein.	Uncharacterized protein.	0.824
CRE_01476	Cre-pfn-1	E3NR52	E3NAA8	CRIB domain-containing protein.	Profilin; Belongs to the profilin family.	0.468
CRE_01476	Cre-rho-1	E3NR52	E3NH51	CRIB domain-containing protein.	CRE-RHO-1 protein.	0.887
CRE_01476	Cre-unc-94	E3NR52	E3M3M3	CRIB domain-containing protein.	CRE-UNC-94 protein.	0.501
CRE_01477	CRE_03486	E3NR53	E3NIA0	WH1 domain-containing protein.	Uncharacterized protein.	0.836
CRE_01477	CRE_15063	E3NR53	E3NMU6	WH1 domain-containing protein.	Uncharacterized protein.	0.836
CRE_01477	CRE_27967	E3NR53	E3NR64	WH1 domain-containing protein.	Uncharacterized protein.	0.824
CRE_01477	CRE_27968	E3NR53	E3NR65	WH1 domain-containing protein.	Uncharacterized protein.	0.824
CRE_01477	Cre-pfn-1	E3NR53	E3NAA8	WH1 domain-containing protein.	Profilin; Belongs to the profilin family.	0.468
CRE_01477	Cre-rho-1	E3NR53	E3NH51	WH1 domain-containing protein.	CRE-RHO-1 protein.	0.836
CRE_01477	Cre-unc-94	E3NR53	E3M3M3	WH1 domain-containing protein.	CRE-UNC-94 protein.	0.501
CRE_03486	CRE_01476	E3NIA0	E3NR52	Uncharacterized protein.	CRIB domain-containing protein.	0.849
CRE_03486	CRE_01477	E3NIA0	E3NR53	Uncharacterized protein.	WH1 domain-containing protein.	0.836
CRE_03486	CRE_10175	E3NIA0	E3M6P9	Uncharacterized protein.	WH1 domain-containing protein.	0.836
CRE_03486	CRE_15735	E3NIA0	E3NFB9	Uncharacterized protein.	PH domain-containing protein.	0.883
CRE_03486	CRE_16652	E3NIA0	E3MAY2	Uncharacterized protein.	PH domain-containing protein.	0.888
CRE_03486	CRE_25422	E3NIA0	E3LT30	Uncharacterized protein.	Uncharacterized protein.	0.679