(64 nodes) PDZ domain network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRE_24483	PDZ domain-containing protein. (94 aa)
	CRE_25030	PDZ domain-containing protein. (123 aa)
	CRE_16574	Uncharacterized protein. (405 aa)
	CRE_15144	PDZ domain-containing protein. (290 aa)
	CRE_29280	PDZ domain-containing protein. (144 aa)
	CRE_15186	PDZ domain-containing protein. (371 aa)
	CRE_22202	Uncharacterized protein. (491 aa)
	CRE_21616	Uncharacterized protein. (360 aa)
	CRE_15046	PDZ domain-containing protein. (239 aa)
	CRE_31560	Uncharacterized protein. (446 aa)
	CRE_30528	PDZ domain-containing protein. (246 aa)
	CRE_21574	PDZ domain-containing protein. (624 aa)
	CRE_12292	Uncharacterized protein. (440 aa)
	CRE_10587	Uncharacterized protein. (274 aa)
	CRE_25779	Uncharacterized protein. (491 aa)
	Cre-zoo-1	CRE-ZOO-1 protein. (1201 aa)
	Cre-par-6	CRE-PAR-6 protein. (311 aa)
	CRE_07736	PDZ domain-containing protein. (417 aa)
	CRE_03336	PDZ domain-containing protein. (171 aa)
	Cre-stn-1	CRE-STN-1 protein. (455 aa)
	Cre-frm-8	CRE-FRM-8 protein. (900 aa)
	Cre-lin-10	CRE-LIN-10 protein. (1003 aa)
	Cre-lin-2	CRE-LIN-2 protein; Belongs to the MAGUK family. (961 aa)
	Cre-tag-60	CRE-TAG-60 protein. (611 aa)
	CRE_14073	PDZ domain-containing protein. (122 aa)
	CRE_12900	PDZ domain-containing protein. (291 aa)
	Cre-pxf-1	CRE-PXF-1 protein. (1476 aa)
	CRE_29891	Uncharacterized protein. (276 aa)
	CRE_29885	Uncharacterized protein. (1093 aa)
	CRE_25686	Uncharacterized protein; Belongs to the MAGUK family. (589 aa)
	Cre-lin-7	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (210 aa)
	Cre-nab-1	CRE-NAB-1 protein. (718 aa)
	CRE_20214	PDZ domain-containing protein. (377 aa)
	Cre-kin-4	CRE-KIN-4 protein. (1655 aa)
	Cre-magi-1	CRE-MAGI-1 protein. (1058 aa)
	CRE_12526	Uncharacterized protein. (407 aa)
	CRE_10208	Uncharacterized protein. (342 aa)
	CRE_10172	PDZ domain-containing protein. (805 aa)
	CRE_10904	PDZ domain-containing protein. (290 aa)
	CRE_10842	PDZ domain-containing protein. (313 aa)
	Cre-dsh-1	CRE-DSH-1 protein. (934 aa)
	Cre-dsh-2	CRE-DSH-2 protein. (718 aa)
	CRE_11661	Uncharacterized protein. (664 aa)
	Cre-afd-1	CRE-AFD-1 protein. (1310 aa)
	Cre-rhgf-1	CRE-RHGF-1 protein. (1312 aa)
	Cre-tag-117	CRE-TAG-117 protein; Belongs to the MAGUK family. (691 aa)
	CRE_05600	PDZ domain-containing protein. (165 aa)
	Cre-cnk-1	CRE-CNK-1 protein. (801 aa)
	Cre-par-3	CRE-PAR-3 protein. (1301 aa)
	CRE_29833	Uncharacterized protein. (585 aa)
	Cre-ptp-1	CRE-PTP-1 protein. (1038 aa)
	Cre-lim-8	CRE-LIM-8 protein. (1176 aa)
	Cre-syd-1	CRE-SYD-1 protein. (973 aa)
	CRE_27316	Rap-GAP domain-containing protein. (998 aa)
	Cre-let-413	CRE-LET-413 protein. (772 aa)
	CRE_28261	PDZ domain-containing protein. (365 aa)
	CRE_28260	PDZ domain-containing protein. (418 aa)
	CRE_18755	PDZ domain-containing protein. (413 aa)
	Cre-mig-5	CRE-MIG-5 protein. (680 aa)
	Cre-mpz-1	CRE-MPZ-1 protein. (2451 aa)
	Cre-shn-1	CRE-SHN-1 protein. (1133 aa)
	Cre-dlg-1	CRE-DLG-1 protein; Belongs to the MAGUK family. (990 aa)
	Cre-unc-10	CRE-UNC-10 protein. (1593 aa)
	Cre-stn-2	CRE-STN-2 protein. (529 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_03336	Cre-lim-8	E3MYN4	E3LSR5	PDZ domain-containing protein.	CRE-LIM-8 protein.	0.414
CRE_05600	CRE_10172	E3M066	E3M6P6	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_10587	E3M066	E3N7A4	PDZ domain-containing protein.	Uncharacterized protein.	0.460
CRE_05600	CRE_10842	E3M066	E3M550	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_11661	E3M066	E3M3Z6	PDZ domain-containing protein.	Uncharacterized protein.	0.460
CRE_05600	CRE_12292	E3M066	E3NEP2	PDZ domain-containing protein.	Uncharacterized protein.	0.563
CRE_05600	CRE_12526	E3M066	E3M7G3	PDZ domain-containing protein.	Uncharacterized protein.	0.700
CRE_05600	CRE_12900	E3M066	E3MQV3	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_14073	E3M066	E3MRD4	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_15046	E3M066	E3NL87	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_15186	E3M066	E3NPY0	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_16574	E3M066	E3NU43	PDZ domain-containing protein.	Uncharacterized protein.	0.700
CRE_05600	CRE_18755	E3M066	E3LJY7	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_20214	E3M066	E3MCP8	PDZ domain-containing protein.	PDZ domain-containing protein.	0.401
CRE_05600	CRE_21574	E3M066	E3NHL3	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_25030	E3M066	E3NUD5	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_25686	E3M066	E3ML35	PDZ domain-containing protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.460
CRE_05600	CRE_27316	E3M066	E3LPN7	PDZ domain-containing protein.	Rap-GAP domain-containing protein.	0.708
CRE_05600	CRE_28260	E3M066	E3LN04	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460
CRE_05600	CRE_28261	E3M066	E3LN05	PDZ domain-containing protein.	PDZ domain-containing protein.	0.460