73 items (Caenorhabditis remanei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRE_09394	AAA domain-containing protein; Belongs to the AAA ATPase family. (416 aa)
	CRE_02019	AAA domain-containing protein; Belongs to the AAA ATPase family. (438 aa)
	Cre-iff-2	Eukaryotic translation initiation factor 5A. (161 aa)
	Cre-cey-1	CRE-CEY-1 protein. (202 aa)
	Cre-lin-28	CRE-LIN-28 protein. (208 aa)
	CRE_23267	OB domain-containing protein. (171 aa)
	CRE_02776	BRCT domain-containing protein. (1202 aa)
	CRE_03575	tRNA-binding domain-containing protein. (129 aa)
	CRE_02717	Uncharacterized protein. (273 aa)
	CRE_09872	tRNA-binding domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (934 aa)
	Cre-dis-3	CRE-DIS-3 protein. (799 aa)
	CRE_10747	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (218 aa)
	CRE_05232	Ribosomal_L2_C domain-containing protein. (321 aa)
	CRE_13733	S1 motif domain-containing protein. (712 aa)
	CRE_24777	Uncharacterized protein. (378 aa)
	Cre-rpt-6	CRE-RPT-6 protein; Belongs to the AAA ATPase family. (408 aa)
	Cre-mcm-3	CRE-MCM-3 protein; Belongs to the MCM family. (814 aa)
	Cre-nars-1	CRE-NARS-1 protein. (545 aa)
	Cre-rps-28	CRE-RPS-28 protein. (65 aa)
	Cre-rpa-2	CRE-RPA-2 protein. (289 aa)
	Cre-lig-1	DNA ligase. (779 aa)
	CRE_23686	Homeobox domain-containing protein. (1035 aa)
	Cre-mcm-2	DNA helicase; Belongs to the MCM family. (877 aa)
	Cre-rpt-4	CRE-RPT-4 protein; Belongs to the AAA ATPase family. (492 aa)
	Cre-mtss-1	CRE-MTSS-1 protein. (169 aa)
	Cre-rpb-7	CRE-RPB-7 protein. (174 aa)
	Cre-lig-4	CRE-LIG-4 protein. (754 aa)
	CRE_20424	Uncharacterized protein. (620 aa)
	Cre-rps-23	CRE-RPS-23 protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	Cre-exos-2	CRE-EXOS-2 protein. (303 aa)
	Cre-brc-2	CRE-BRC-2 protein. (402 aa)
	Cre-mcm-5	DNA helicase; Belongs to the MCM family. (759 aa)
	CRE_28736	Uncharacterized protein. (142 aa)
	Cre-nars-2	CRE-NARS-2 protein. (444 aa)
	CRE_01039	Mcm10 domain-containing protein. (692 aa)
	CRE_23950	S1 motif domain-containing protein. (770 aa)
	Cre-rpl-2	CRE-RPL-2 protein. (260 aa)
	CRE_21144	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (161 aa)
	Cre-emb-5	Suppressor of Ty 6 homolog; May regulate transcriptional elongation by RNA polymerase II. (1521 aa)
	Cre-rpb-8	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (148 aa)
	CRE_20290	Uncharacterized protein. (428 aa)
	CRE_12804	Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (155 aa)
	Cre-mars-1	CRE-MARS-1 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (920 aa)
	Cre-mog-5	CRE-MOG-5 protein. (1208 aa)
	Cre-cel-1	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (616 aa)
	Cre-mcm-4	DNA helicase; Belongs to the MCM family. (817 aa)
	CRE_04763	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. (871 aa)
	Cre-exos-1	CRE-EXOS-1 protein. (213 aa)
	Cre-cey-4	CRE-CEY-4 protein. (289 aa)
	CRE_03750	S1 motif domain-containing protein. (346 aa)
	CRE_03663	Uncharacterized protein. (305 aa)
	CRE_03854	POT1PC domain-containing protein. (134 aa)
	CRE_03853	Uncharacterized protein. (616 aa)
	CRE_03641	CSD_1 domain-containing protein. (264 aa)
	CRE_03839	CSD_1 domain-containing protein. (263 aa)
	CRE_03184	AAA domain-containing protein; Belongs to the AAA ATPase family. (443 aa)
	CRE_03174	Uncharacterized protein. (160 aa)
	Cre-let-716	CRE-LET-716 protein. (1758 aa)
	Cre-exos-3	CRE-EXOS-3 protein. (271 aa)
	Cre-rpa-4	CRE-RPA-4 protein. (292 aa)
	Cre-rpt-2	CRE-RPT-2 protein; Belongs to the AAA ATPase family. (443 aa)
	CRE_30701	S1-like domain-containing protein. (178 aa)
	CRE_30699	Uncharacterized protein. (234 aa)
	Cre-dars-1	CRE-DARS-1 protein. (540 aa)
	Cre-iff-1	Eukaryotic translation initiation factor 5A. (162 aa)
	Cre-mcm-6	DNA helicase; Belongs to the MCM family. (828 aa)
	Cre-rpa-1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (656 aa)
	Cre-kars-1	Lysine--tRNA ligase. (596 aa)
	Cre-dars-2	CRE-DARS-2 protein. (637 aa)
	Cre-rpt-1	CRE-RPT-1 protein; Belongs to the AAA ATPase family. (435 aa)
	CRE_28272	AAA domain-containing protein; Belongs to the AAA ATPase family. (409 aa)
	Cre-rpt-5	CRE-RPT-5 protein; Belongs to the AAA ATPase family. (430 aa)
	Cre-mcm-7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (730 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_01039	CRE_02776	E3MI74	E3NTU5	Mcm10 domain-containing protein.	BRCT domain-containing protein.	0.517
CRE_01039	Cre-lig-1	E3MI74	E3N788	Mcm10 domain-containing protein.	DNA ligase.	0.597
CRE_01039	Cre-lig-4	E3MI74	E3MWG0	Mcm10 domain-containing protein.	CRE-LIG-4 protein.	0.429
CRE_01039	Cre-mcm-2	E3MI74	E3N2S4	Mcm10 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.997
CRE_01039	Cre-mcm-3	E3MI74	E3NCJ2	Mcm10 domain-containing protein.	CRE-MCM-3 protein; Belongs to the MCM family.	0.998
CRE_01039	Cre-mcm-4	E3MI74	E3M3H8	Mcm10 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.999
CRE_01039	Cre-mcm-5	E3MI74	E3ML13	Mcm10 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.998
CRE_01039	Cre-mcm-6	E3MI74	E3LS69	Mcm10 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.999
CRE_01039	Cre-mcm-7	E3MI74	E3LKW3	Mcm10 domain-containing protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.993
CRE_01039	Cre-rpa-1	E3MI74	E3LRP9	Mcm10 domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.844
CRE_01039	Cre-rpa-2	E3MI74	E3N7I0	Mcm10 domain-containing protein.	CRE-RPA-2 protein.	0.731
CRE_01039	Cre-rpa-4	E3MI74	E3LVD8	Mcm10 domain-containing protein.	CRE-RPA-4 protein.	0.731
CRE_02019	CRE_03184	E3LGV3	E3LX06	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.992
CRE_02019	CRE_09394	E3LGV3	E3LIK9	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.992
CRE_02019	CRE_12804	E3LGV3	E3M7Y9	AAA domain-containing protein; Belongs to the AAA ATPase family.	Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family.	0.470
CRE_02019	CRE_28272	E3LGV3	E3LN27	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.983
CRE_02019	Cre-rpl-2	E3LGV3	E3MF85	AAA domain-containing protein; Belongs to the AAA ATPase family.	CRE-RPL-2 protein.	0.525
CRE_02019	Cre-rpt-1	E3LGV3	E3LPW3	AAA domain-containing protein; Belongs to the AAA ATPase family.	CRE-RPT-1 protein; Belongs to the AAA ATPase family.	0.998
CRE_02019	Cre-rpt-2	E3LGV3	E3LUK4	AAA domain-containing protein; Belongs to the AAA ATPase family.	CRE-RPT-2 protein; Belongs to the AAA ATPase family.	0.952
CRE_02019	Cre-rpt-4	E3LGV3	E3N297	AAA domain-containing protein; Belongs to the AAA ATPase family.	CRE-RPT-4 protein; Belongs to the AAA ATPase family.	0.981