STRINGSTRING
CRE_25761 CRE_25761 CRE_05114 CRE_05114 CRE_05137 CRE_05137 CRE_16996 CRE_16996 CRE_15697 CRE_15697 Cre-pbs-1 Cre-pbs-1 Cre-mcm-3 Cre-mcm-3 Cre-rpt-6 Cre-rpt-6 CRE_19472 CRE_19472 Cre-pas-2 Cre-pas-2 CRE_30262 CRE_30262 CRE_25974 CRE_25974 CRE_27959 CRE_27959 CRE_24376 CRE_24376 CRE_07953 CRE_07953 CRE_00341 CRE_00341 CRE_02091 CRE_02091 Cre-rpn-12 Cre-rpn-12 Cre-rpn-9 Cre-rpn-9 Cre-orc-2 Cre-orc-2 CRE_02278 CRE_02278 Cre-dnj-23 Cre-dnj-23 CRE_02019 CRE_02019 Cre-pas-7 Cre-pas-7 CRE_09394 CRE_09394 MCM7 MCM7 MCM7-2 MCM7-2 Cre-mcm-7 Cre-mcm-7 Cre-cdt-1 Cre-cdt-1 CRE_28077 CRE_28077 Cre-rpt-5 Cre-rpt-5 Cre-rpn-10 Cre-rpn-10 Cre-cye-1 Cre-cye-1 CRE_28562 CRE_28562 CRE_28272 CRE_28272 Cre-rpt-1 Cre-rpt-1 CRE_27080 CRE_27080 CRE_26482 CRE_26482 CRE_26065 CRE_26065 CRE_26066 CRE_26066 Cre-rpa-1 Cre-rpa-1 Cre-mcm-6 Cre-mcm-6 Cre-pri-1 Cre-pri-1 CRE_25584 CRE_25584 CRE_25344 CRE_25344 Cre-pbs-6 Cre-pbs-6 CRE_25146 CRE_25146 CRE_25147 CRE_25147 CRE_31157 CRE_31157 Cre-pas-1 Cre-pas-1 Cre-akt-1 Cre-akt-1 Cre-pas-6 Cre-pas-6 Cre-rpt-2 Cre-rpt-2 Cre-pbs-7 Cre-pbs-7 Cre-pas-5 Cre-pas-5 Cre-ubq-2 Cre-ubq-2 CRE_03063 CRE_03063 CRE_03064 CRE_03064 CRE_02873 CRE_02873 CRE_03090 CRE_03090 CRE_03093 CRE_03093 CRE_03094 CRE_03094 CRE_03095 CRE_03095 CRE_03096 CRE_03096 CRE_03097 CRE_03097 CRE_03098 CRE_03098 CRE_02894 CRE_02894 CRE_02895 CRE_02895 CRE_02896 CRE_02896 Cre-rpn-2 Cre-rpn-2 CRE_03180 CRE_03180 CRE_03184 CRE_03184 CRE_02825 CRE_02825 CRE_02827 CRE_02827 CRE_03013 CRE_03013 CRE_02828 CRE_02828 CRE_03649 CRE_03649 CRE_03983 CRE_03983 CRE_04677 CRE_04677 Cre-ubq-1 Cre-ubq-1 CRE_04544 CRE_04544 Cre-paa-1 Cre-paa-1 Cre-skpt-1 Cre-skpt-1 Cre-div-1 Cre-div-1 Cre-cul-1 Cre-cul-1 CRE_04614 CRE_04614 CRE_04615 CRE_04615 CRE_06288 CRE_06288 Cre-cyh-1 Cre-cyh-1 Cre-mcm-4 Cre-mcm-4 Cre-pbs-3 Cre-pbs-3 CRE_11952 CRE_11952 CRE_10866 CRE_10866 CRE_10867 CRE_10867 CRE_11090 CRE_11090 Cre-skr-16 Cre-skr-16 CRE_13961 CRE_13961 CRE_14692 CRE_14692 CRE_14579 CRE_14579 CRE_17162 CRE_17162 Cre-rpn-6 Cre-rpn-6 CRE_20353 CRE_20353 Cre-rsa-1 Cre-rsa-1 Cre-pbs-4 Cre-pbs-4 CRE_23919 CRE_23919 Cre-rpn-8 Cre-rpn-8 Cre-cdc-6 Cre-cdc-6 CRE_22876 CRE_22876 CRE_22877 CRE_22877 Cre-rpn-3 Cre-rpn-3 CRE_01039 CRE_01039 CRE_01016 CRE_01016 CRE_09622 CRE_09622 CRE_19220 CRE_19220 Cre-skr-21 Cre-skr-21 Cre-skr-19 Cre-skr-19 Cre-skr-20 Cre-skr-20 CRE_27577 CRE_27577 CRE_27578 CRE_27578 Cre-mcm-5 Cre-mcm-5 CRE_25701 CRE_25701 CRE_04056 CRE_04056 CRE_04057 CRE_04057 CRE_04134 CRE_04134 Cre-cki-1 Cre-cki-1 Cre-cki-2 Cre-cki-2 CRE_07639 CRE_07639 CRE_12079 CRE_12079 Cre-rpn-11 Cre-rpn-11 Cre-let-92 Cre-let-92 Cre-ppfr-1 Cre-ppfr-1 CRE_19863 CRE_19863 CRE_19800 CRE_19800 CRE_21370 CRE_21370 CRE_23600 CRE_23600 Cre-ubl-1 Cre-ubl-1 CRE_01156 CRE_01156 CRE_09709 CRE_09709 Cre-pas-3 Cre-pas-3 Cre-rpn-5 Cre-rpn-5 Cre-mnat-1 Cre-mnat-1 CRE_06891 CRE_06891 CRE_06833 CRE_06833 CRE_12205 CRE_12205 Cre-pri-2 Cre-pri-2 Cre-pbs-5 Cre-pbs-5 CRE_14909 CRE_14909 Cre-rpt-4 Cre-rpt-4 Cre-pole-2 Cre-pole-2 Cre-pbs-2 Cre-pbs-2 Cre-mcm-2 Cre-mcm-2 Cre-rpn-1 Cre-rpn-1 Cre-rpn-7 Cre-rpn-7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRE_25761PCI domain-containing protein. (372 aa)
CRE_05114Uncharacterized protein; Belongs to the cyclin family. (340 aa)
CRE_05137Uncharacterized protein; Belongs to the cyclin family. (358 aa)
CRE_16996Cullin domain-containing protein; Belongs to the cullin family. (244 aa)
CRE_15697Ribosomal_L40e domain-containing protein. (62 aa)
Cre-pbs-1Proteasome subunit beta. (239 aa)
Cre-mcm-3CRE-MCM-3 protein; Belongs to the MCM family. (814 aa)
Cre-rpt-6CRE-RPT-6 protein; Belongs to the AAA ATPase family. (408 aa)
CRE_19472Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (95 aa)
Cre-pas-2Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (231 aa)
CRE_30262Uncharacterized protein. (101 aa)
CRE_25974AAA_lid_3 domain-containing protein. (114 aa)
CRE_27959KxDL domain-containing protein. (114 aa)
CRE_24376Uncharacterized protein. (63 aa)
CRE_07953Serine/threonine-protein phosphatase. (331 aa)
CRE_00341Uncharacterized protein; Belongs to the SKP1 family. (154 aa)
CRE_02091Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (155 aa)
Cre-rpn-12CRE-RPN-12 protein. (250 aa)
Cre-rpn-9CRE-RPN-9 protein. (390 aa)
Cre-orc-2CRE-ORC-2 protein. (430 aa)
CRE_02278Uncharacterized protein. (926 aa)
Cre-dnj-23CRE-DNJ-23 protein. (243 aa)
CRE_02019AAA domain-containing protein; Belongs to the AAA ATPase family. (438 aa)
Cre-pas-7Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa)
CRE_09394AAA domain-containing protein; Belongs to the AAA ATPase family. (416 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (440 aa)
MCM7-2DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (77 aa)
Cre-mcm-7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (730 aa)
Cre-cdt-1CRE-CDT-1 protein. (705 aa)
CRE_28077Cyclin N-terminal domain-containing protein. (538 aa)
Cre-rpt-5CRE-RPT-5 protein; Belongs to the AAA ATPase family. (430 aa)
Cre-rpn-10CRE-RPN-10 protein. (350 aa)
Cre-cye-1CRE-CYE-1 protein; Belongs to the cyclin family. (550 aa)
CRE_28562Uncharacterized protein; Belongs to the AAA ATPase family. (309 aa)
CRE_28272AAA domain-containing protein; Belongs to the AAA ATPase family. (409 aa)
Cre-rpt-1CRE-RPT-1 protein; Belongs to the AAA ATPase family. (435 aa)
CRE_27080Uncharacterized protein. (385 aa)
CRE_26482Uncharacterized protein. (197 aa)
CRE_26065CBFD_NFYB_HMF domain-containing protein. (212 aa)
CRE_26066CBFD_NFYB_HMF domain-containing protein. (212 aa)
Cre-rpa-1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (656 aa)
Cre-mcm-6DNA helicase; Belongs to the MCM family. (828 aa)
Cre-pri-1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (410 aa)
CRE_25584MPN domain-containing protein. (319 aa)
CRE_25344Uncharacterized protein; Belongs to the cyclin family. (483 aa)
Cre-pbs-6Proteasome subunit beta. (258 aa)
CRE_25146Uncharacterized protein. (568 aa)
CRE_25147CPG4 domain-containing protein. (713 aa)
CRE_31157EF-hand domain-containing protein. (385 aa)
Cre-pas-1Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (246 aa)
Cre-akt-1Non-specific serine/threonine protein kinase. (612 aa)
Cre-pas-6Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (271 aa)
Cre-rpt-2CRE-RPT-2 protein; Belongs to the AAA ATPase family. (443 aa)
Cre-pbs-7Proteasome subunit beta; Belongs to the peptidase T1B family. (236 aa)
Cre-pas-5Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (258 aa)
Cre-ubq-2CRE-UBQ-2 protein. (128 aa)
CRE_03063Uncharacterized protein; Belongs to the SKP1 family. (210 aa)
CRE_03064Uncharacterized protein; Belongs to the SKP1 family. (210 aa)
CRE_02873Uncharacterized protein; Belongs to the SKP1 family. (208 aa)
CRE_03090Uncharacterized protein; Belongs to the SKP1 family. (180 aa)
CRE_03093Uncharacterized protein; Belongs to the SKP1 family. (249 aa)
CRE_03094Uncharacterized protein; Belongs to the SKP1 family. (244 aa)
CRE_03095Uncharacterized protein; Belongs to the SKP1 family. (201 aa)
CRE_03096Uncharacterized protein; Belongs to the SKP1 family. (196 aa)
CRE_03097Uncharacterized protein; Belongs to the SKP1 family. (208 aa)
CRE_03098Uncharacterized protein; Belongs to the SKP1 family. (204 aa)
CRE_02894Uncharacterized protein; Belongs to the SKP1 family. (210 aa)
CRE_02895Uncharacterized protein; Belongs to the SKP1 family. (205 aa)
CRE_02896Uncharacterized protein; Belongs to the SKP1 family. (194 aa)
Cre-rpn-226S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (978 aa)
CRE_03180CBFD_NFYB_HMF domain-containing protein. (150 aa)
CRE_03184AAA domain-containing protein; Belongs to the AAA ATPase family. (443 aa)
CRE_02825Uncharacterized protein; Belongs to the SKP1 family. (177 aa)
CRE_02827Uncharacterized protein; Belongs to the SKP1 family. (207 aa)
CRE_03013Uncharacterized protein; Belongs to the SKP1 family. (209 aa)
CRE_02828Uncharacterized protein; Belongs to the SKP1 family. (209 aa)
CRE_03649Uncharacterized protein; Belongs to the SKP1 family. (147 aa)
CRE_03983Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (446 aa)
CRE_04677DNA polymerase. (1489 aa)
Cre-ubq-1CRE-UBQ-1 protein. (920 aa)
CRE_04544MADF domain-containing protein. (587 aa)
Cre-paa-1CRE-PAA-1 protein. (618 aa)
Cre-skpt-1CRE-SKPT-1 protein. (415 aa)
Cre-div-1DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (581 aa)
Cre-cul-1CRE-CUL-1 protein; Belongs to the cullin family. (798 aa)
CRE_04614Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (665 aa)
CRE_04615Uncharacterized protein. (398 aa)
CRE_06288MPN domain-containing protein. (323 aa)
Cre-cyh-1CRE-CYH-1 protein. (330 aa)
Cre-mcm-4DNA helicase; Belongs to the MCM family. (817 aa)
Cre-pbs-3Proteasome subunit beta. (204 aa)
CRE_11952Uncharacterized protein; Belongs to the SKP1 family. (179 aa)
CRE_10866Uncharacterized protein. (449 aa)
CRE_10867Uncharacterized protein. (264 aa)
CRE_11090PCI domain-containing protein. (489 aa)
Cre-skr-16CRE-SKR-16 protein; Belongs to the SKP1 family. (223 aa)
CRE_13961DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2200 aa)
CRE_14692Uncharacterized protein. (89 aa)
CRE_14579AAA domain-containing protein; Belongs to the AAA ATPase family. (404 aa)
CRE_17162Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (174 aa)
Cre-rpn-6CRE-RPN-6 protein. (420 aa)
CRE_20353Uncharacterized protein. (507 aa)
Cre-rsa-1CRE-RSA-1 protein. (419 aa)
Cre-pbs-4Proteasome subunit beta. (204 aa)
CRE_23919Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (106 aa)
Cre-rpn-8CRE-RPN-8 protein. (362 aa)
Cre-cdc-6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (553 aa)
CRE_22876Uncharacterized protein; Belongs to the SKP1 family. (186 aa)
CRE_22877Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (239 aa)
Cre-rpn-3CRE-RPN-3 protein. (506 aa)
CRE_01039Mcm10 domain-containing protein. (692 aa)
CRE_01016Uncharacterized protein. (266 aa)
CRE_09622CULLIN_2 domain-containing protein; Belongs to the cullin family. (487 aa)
CRE_19220Ubiquitin-like domain-containing protein. (81 aa)
Cre-skr-21CRE-SKR-21 protein; Belongs to the SKP1 family. (163 aa)
Cre-skr-19CRE-SKR-19 protein; Belongs to the SKP1 family. (150 aa)
Cre-skr-20CRE-SKR-20 protein; Belongs to the SKP1 family. (168 aa)
CRE_27577Uncharacterized protein. (822 aa)
CRE_27578Uncharacterized protein. (604 aa)
Cre-mcm-5DNA helicase; Belongs to the MCM family. (759 aa)
CRE_25701Uncharacterized protein. (117 aa)
CRE_04056Uncharacterized protein; Belongs to the SKP1 family. (190 aa)
CRE_04057Uncharacterized protein; Belongs to the SKP1 family. (179 aa)
CRE_04134Uncharacterized protein; Belongs to the SKP1 family. (203 aa)
Cre-cki-1CRE-CKI-1 protein. (185 aa)
Cre-cki-2CRE-CKI-2 protein. (283 aa)
CRE_07639Uncharacterized protein; Belongs to the SKP1 family. (203 aa)
CRE_12079CULLIN_2 domain-containing protein; Belongs to the cullin family. (783 aa)
Cre-rpn-11CRE-RPN-11 protein. (312 aa)
Cre-let-92Serine/threonine-protein phosphatase. (333 aa)
Cre-ppfr-1CRE-PPFR-1 protein. (1526 aa)
CRE_19863Uncharacterized protein; Belongs to the cyclin family. (330 aa)
CRE_19800Uncharacterized protein; Belongs to the cyclin family. (327 aa)
CRE_21370CULLIN_2 domain-containing protein; Belongs to the cullin family. (751 aa)
CRE_23600AAA domain-containing protein; Belongs to the AAA ATPase family. (329 aa)
Cre-ubl-1CRE-UBL-1 protein. (160 aa)
CRE_01156Uncharacterized protein; Belongs to the SKP1 family. (291 aa)
CRE_09709Uncharacterized protein; Belongs to the SKP1 family. (171 aa)
Cre-pas-3Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa)
Cre-rpn-5CRE-RPN-5 protein. (507 aa)
Cre-mnat-1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (313 aa)
CRE_06891Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (243 aa)
CRE_06833Uncharacterized protein; Belongs to the SKP1 family. (179 aa)
CRE_12205PCI domain-containing protein. (472 aa)
Cre-pri-2DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (504 aa)
Cre-pbs-5CRE-PBS-5 protein. (284 aa)
CRE_14909KxDL domain-containing protein. (72 aa)
Cre-rpt-4CRE-RPT-4 protein; Belongs to the AAA ATPase family. (492 aa)
Cre-pole-2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (520 aa)
Cre-pbs-2CRE-PBS-2 protein. (290 aa)
Cre-mcm-2DNA helicase; Belongs to the MCM family. (877 aa)
Cre-rpn-126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (989 aa)
Cre-rpn-7CRE-RPN-7 protein. (409 aa)
Your Current Organism:
Caenorhabditis remanei
NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris
Server load: low (24%) [HD]