STRINGSTRING
CRE_26733 CRE_26733 CRE_26734 CRE_26734 CRE_03330 CRE_03330 CRE_08432 CRE_08432 CRE_12174 CRE_12174 Cre-hus-1 Cre-hus-1 CRE_24376 CRE_24376 CRE_04493 CRE_04493 CRE_22274 CRE_22274 CRE_01515 CRE_01515 CRE_22260 CRE_22260 Cre-his-39 Cre-his-39 CRE_15163 CRE_15163 CRE_15162 CRE_15162 CRE_20137 CRE_20137 Cre-pbs-4 Cre-pbs-4 Cre-rpn-8 Cre-rpn-8 Cre-cdc-6 Cre-cdc-6 CRE_14179 CRE_14179 Cre-pbs-5 Cre-pbs-5 CRE_14909 CRE_14909 Cre-rpt-4 Cre-rpt-4 Cre-pbs-2 Cre-pbs-2 Cre-mcm-2 Cre-mcm-2 CRE_22594 CRE_22594 CRE_21970 CRE_21970 CRE_25814 CRE_25814 CRE_25815 CRE_25815 CRE_14254 CRE_14254 Cre-wee-1.3 Cre-wee-1.3 CRE_06993 CRE_06993 CRE_10610 CRE_10610 CRE_13081 CRE_13081 Cre-pbs-1 Cre-pbs-1 Cre-mcm-3 Cre-mcm-3 Cre-rpt-6 Cre-rpt-6 CRE_24236 CRE_24236 Cre-him-6 Cre-him-6 CRE_14310 CRE_14310 CRE_14321 CRE_14321 Cre-exo-1 Cre-exo-1 CRE_30476 CRE_30476 CRE_22129 CRE_22129 CRE_22123 CRE_22123 CRE_25932 CRE_25932 CRE_25927 CRE_25927 CRE_30235 CRE_30235 CRE_04379 CRE_04379 CRE_15218 CRE_15218 CRE_25974 CRE_25974 CRE_11542 CRE_11542 CRE_27959 CRE_27959 CRE_07135 CRE_07135 CRE_07136 CRE_07136 CRE_01475 CRE_01475 CRE_17749 CRE_17749 Cre-rfc-2 Cre-rfc-2 CRE_20701 CRE_20701 Cre-chk-2 Cre-chk-2 Cre-cyb-3 Cre-cyb-3 CRE_22391 CRE_22391 CRE_17916 CRE_17916 Cre-glo-4 Cre-glo-4 CRE_19658 CRE_19658 Cre-atl-1 Cre-atl-1 CRE_20353 CRE_20353 Cre-rfc-4 Cre-rfc-4 CRE_14579 CRE_14579 CRE_14692 CRE_14692 Cre-brc-1 Cre-brc-1 CRE_01514 CRE_01514 CRE_10017 CRE_10017 Cre-hpr-17 Cre-hpr-17 Cre-rpn-12 Cre-rpn-12 Cre-rpn-9 Cre-rpn-9 Cre-orc-2 Cre-orc-2 Cre-dna-2 Cre-dna-2 Cre-pas-7 Cre-pas-7 CRE_09394 CRE_09394 CRE_18472 CRE_18472 CRE_18971 CRE_18971 Cre-his-31 Cre-his-31 MCM7 MCM7 MCM7-2 MCM7-2 Cre-chk-1 Cre-chk-1 Cre-mcm-7 Cre-mcm-7 Cre-rpt-5 Cre-rpt-5 Cre-rpn-10 Cre-rpn-10 CRE_28562 CRE_28562 CRE_28272 CRE_28272 CRE_27101 CRE_27101 CRE_27102 CRE_27102 CRE_27134 CRE_27134 Cre-rpt-1 Cre-rpt-1 Cre-rad-50 Cre-rad-50 CRE_27381 CRE_27381 CRE_26482 CRE_26482 Cre-wrn-1 Cre-wrn-1 Cre-rpa-1 Cre-rpa-1 Cre-mcm-6 Cre-mcm-6 CRE_25146 CRE_25146 CRE_25147 CRE_25147 Cre-pas-6 Cre-pas-6 Cre-rpt-2 Cre-rpt-2 Cre-pbs-7 Cre-pbs-7 Cre-pas-4 Cre-pas-4 Cre-pas-5 Cre-pas-5 Cre-mus-101 Cre-mus-101 Cre-rpn-2 Cre-rpn-2 CRE_03184 CRE_03184 CRE_03817 CRE_03817 CRE_03842 CRE_03842 CRE_03983 CRE_03983 Cre-com-1 Cre-com-1 Cre-ubq-1 Cre-ubq-1 Cre-hpr-9 Cre-hpr-9 CRE_04614 CRE_04614 CRE_04615 CRE_04615 CRE_05743 CRE_05743 CRE_05746 CRE_05746 CRE_05547 CRE_05547 CRE_06288 CRE_06288 Cre-ftt-2 Cre-ftt-2 CRE_08032 CRE_08032 Cre-mcm-4 Cre-mcm-4 Cre-hsr-9 Cre-hsr-9 CRE_08190 CRE_08190 Cre-pbs-3 Cre-pbs-3 Cre-cyb-1 Cre-cyb-1 CRE_10866 CRE_10866 CRE_10867 CRE_10867 CRE_11090 CRE_11090 Cre-rfc-3 Cre-rfc-3 CRE_10300 CRE_10300 CRE_22779 CRE_22779 Cre-rpn-3 Cre-rpn-3 Cre-top-3 Cre-top-3 CRE_01039 CRE_01039 Cre-mrt-2 Cre-mrt-2 CRE_02382 CRE_02382 CRE_19143 CRE_19143 CRE_27630 CRE_27630 CRE_27631 CRE_27631 Cre-mcm-5 Cre-mcm-5 CRE_29915 CRE_29915 CRE_06764 CRE_06764 Cre-mdt-30 Cre-mdt-30 CRE_08348 CRE_08348 Cre-rpn-11 Cre-rpn-11 Cre-mre-11 Cre-mre-11 Cre-par-5 Cre-par-5 CRE_21389 CRE_21389 CRE_21390 CRE_21390 CRE_20858 CRE_20858 CRE_23600 CRE_23600 CRE_22920 CRE_22920 CRE_09708 CRE_09708 CRE_19313 CRE_19313 CRE_19314 CRE_19314 CRE_19288 CRE_19288 Cre-rpn-5 Cre-rpn-5 CRE_27745 CRE_27745 CRE_11299 CRE_11299 CRE_27746 CRE_27746
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRE_26733Uncharacterized protein. (338 aa)
CRE_26734Uncharacterized protein. (103 aa)
CRE_03330Reverse transcriptase domain-containing protein. (294 aa)
CRE_08432Uncharacterized protein. (1881 aa)
CRE_12174Uncharacterized protein. (260 aa)
Cre-hus-1Checkpoint protein; Belongs to the HUS1 family. (292 aa)
CRE_24376Uncharacterized protein. (63 aa)
CRE_04493AAA domain-containing protein. (252 aa)
CRE_22274Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (355 aa)
CRE_01515Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (90 aa)
CRE_22260Protein kinase domain-containing protein. (194 aa)
Cre-his-39Histone H2B; Belongs to the histone H2B family. (64 aa)
CRE_15163Reverse transcriptase domain-containing protein. (376 aa)
CRE_15162Uncharacterized protein. (144 aa)
CRE_20137Uncharacterized protein. (642 aa)
Cre-pbs-4Proteasome subunit beta. (204 aa)
Cre-rpn-8CRE-RPN-8 protein. (362 aa)
Cre-cdc-6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (553 aa)
CRE_14179Reverse transcriptase domain-containing protein. (373 aa)
Cre-pbs-5CRE-PBS-5 protein. (284 aa)
CRE_14909KxDL domain-containing protein. (72 aa)
Cre-rpt-4CRE-RPT-4 protein; Belongs to the AAA ATPase family. (492 aa)
Cre-pbs-2CRE-PBS-2 protein. (290 aa)
Cre-mcm-2DNA helicase; Belongs to the MCM family. (877 aa)
CRE_22594Protein kinase domain-containing protein. (504 aa)
CRE_21970Uncharacterized protein. (98 aa)
CRE_25814Uncharacterized protein. (1868 aa)
CRE_25815Uncharacterized protein. (813 aa)
CRE_14254Reverse transcriptase domain-containing protein. (376 aa)
Cre-wee-1.3CRE-WEE-1.3 protein. (657 aa)
CRE_06993Reverse transcriptase domain-containing protein. (713 aa)
CRE_10610Uncharacterized protein. (192 aa)
CRE_13081Reverse transcriptase domain-containing protein. (376 aa)
Cre-pbs-1Proteasome subunit beta. (239 aa)
Cre-mcm-3CRE-MCM-3 protein; Belongs to the MCM family. (814 aa)
Cre-rpt-6CRE-RPT-6 protein; Belongs to the AAA ATPase family. (408 aa)
CRE_24236Reverse transcriptase domain-containing protein. (321 aa)
Cre-him-6CRE-HIM-6 protein. (1039 aa)
CRE_14310Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (342 aa)
CRE_14321Protein kinase domain-containing protein. (310 aa)
Cre-exo-1CRE-EXO-1 protein. (637 aa)
CRE_30476Reverse transcriptase domain-containing protein. (923 aa)
CRE_22129Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (425 aa)
CRE_22123Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (341 aa)
CRE_25932Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (408 aa)
CRE_25927Protein kinase domain-containing protein. (336 aa)
CRE_30235Reverse transcriptase domain-containing protein. (418 aa)
CRE_04379Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (720 aa)
CRE_15218Histone H2B; Belongs to the histone H2B family. (122 aa)
CRE_25974AAA_lid_3 domain-containing protein. (114 aa)
CRE_11542Reverse transcriptase domain-containing protein. (294 aa)
CRE_27959KxDL domain-containing protein. (114 aa)
CRE_07135PIEZO domain-containing protein. (844 aa)
CRE_07136Uncharacterized protein. (134 aa)
CRE_01475Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (292 aa)
CRE_17749Uncharacterized protein. (1020 aa)
Cre-rfc-2CRE-RFC-2 protein. (329 aa)
CRE_20701Uncharacterized protein. (751 aa)
Cre-chk-2CRE-CHK-2 protein; Belongs to the protein kinase superfamily. (480 aa)
Cre-cyb-3CRE-CYB-3 protein; Belongs to the cyclin family. (398 aa)
CRE_22391Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (322 aa)
CRE_17916Protein kinase domain-containing protein. (288 aa)
Cre-glo-4CRE-GLO-4 protein. (1411 aa)
CRE_19658Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (294 aa)
Cre-atl-1CRE-ATL-1 protein. (2313 aa)
CRE_20353Uncharacterized protein. (507 aa)
Cre-rfc-4CRE-RFC-4 protein. (362 aa)
CRE_14579AAA domain-containing protein; Belongs to the AAA ATPase family. (404 aa)
CRE_14692Uncharacterized protein. (89 aa)
Cre-brc-1CRE-BRC-1 protein. (593 aa)
CRE_01514Histone H2B; Belongs to the histone H2B family. (122 aa)
CRE_10017Histone H2B; Belongs to the histone H2B family. (128 aa)
Cre-hpr-17CRE-HPR-17 protein. (506 aa)
Cre-rpn-12CRE-RPN-12 protein. (250 aa)
Cre-rpn-9CRE-RPN-9 protein. (390 aa)
Cre-orc-2CRE-ORC-2 protein. (430 aa)
Cre-dna-2CRE-DNA-2 protein. (1084 aa)
Cre-pas-7Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa)
CRE_09394AAA domain-containing protein; Belongs to the AAA ATPase family. (416 aa)
CRE_18472Tudor domain-containing protein. (638 aa)
CRE_18971Histone H2B; Belongs to the histone H2B family. (163 aa)
Cre-his-31Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (440 aa)
MCM7-2DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (77 aa)
Cre-chk-1CRE-CHK-1 protein. (515 aa)
Cre-mcm-7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (730 aa)
Cre-rpt-5CRE-RPT-5 protein; Belongs to the AAA ATPase family. (430 aa)
Cre-rpn-10CRE-RPN-10 protein. (350 aa)
CRE_28562Uncharacterized protein; Belongs to the AAA ATPase family. (309 aa)
CRE_28272AAA domain-containing protein; Belongs to the AAA ATPase family. (409 aa)
CRE_27101BLM10_mid domain-containing protein. (729 aa)
CRE_27102DUF3437 domain-containing protein. (649 aa)
CRE_27134Uncharacterized protein. (1926 aa)
Cre-rpt-1CRE-RPT-1 protein; Belongs to the AAA ATPase family. (435 aa)
Cre-rad-50CRE-RAD-50 protein. (1311 aa)
CRE_27381Histone H2B; Belongs to the histone H2B family. (156 aa)
CRE_26482Uncharacterized protein. (197 aa)
Cre-wrn-1CRE-WRN-1 protein. (1081 aa)
Cre-rpa-1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (656 aa)
Cre-mcm-6DNA helicase; Belongs to the MCM family. (828 aa)
CRE_25146Uncharacterized protein. (568 aa)
CRE_25147CPG4 domain-containing protein. (713 aa)
Cre-pas-6Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (271 aa)
Cre-rpt-2CRE-RPT-2 protein; Belongs to the AAA ATPase family. (443 aa)
Cre-pbs-7Proteasome subunit beta; Belongs to the peptidase T1B family. (236 aa)
Cre-pas-4Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (253 aa)
Cre-pas-5Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (258 aa)
Cre-mus-101CRE-MUS-101 protein. (1198 aa)
Cre-rpn-226S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (978 aa)
CRE_03184AAA domain-containing protein; Belongs to the AAA ATPase family. (443 aa)
CRE_03817Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2161 aa)
CRE_03842DUF1767 domain-containing protein. (975 aa)
CRE_03983Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (446 aa)
Cre-com-1CRE-COM-1 protein. (586 aa)
Cre-ubq-1CRE-UBQ-1 protein. (920 aa)
Cre-hpr-9CRE-HPR-9 protein. (568 aa)
CRE_04614Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (665 aa)
CRE_04615Uncharacterized protein. (398 aa)
CRE_05743Histone H2B; Belongs to the histone H2B family. (163 aa)
CRE_05746Histone H2B; Belongs to the histone H2B family. (120 aa)
CRE_05547Histone H2B; Belongs to the histone H2B family. (163 aa)
CRE_06288MPN domain-containing protein. (323 aa)
Cre-ftt-2CRE-FTT-2 protein; Belongs to the 14-3-3 family. (248 aa)
CRE_08032Histone H2B; Belongs to the histone H2B family. (123 aa)
Cre-mcm-4DNA helicase; Belongs to the MCM family. (817 aa)
Cre-hsr-9CRE-HSR-9 protein. (1301 aa)
CRE_08190Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (195 aa)
Cre-pbs-3Proteasome subunit beta. (204 aa)
Cre-cyb-1CRE-CYB-1 protein; Belongs to the cyclin family. (373 aa)
CRE_10866Uncharacterized protein. (449 aa)
CRE_10867Uncharacterized protein. (264 aa)
CRE_11090PCI domain-containing protein. (489 aa)
Cre-rfc-3CRE-RFC-3 protein. (370 aa)
CRE_10300SAP domain-containing protein. (430 aa)
CRE_22779DUF1767 domain-containing protein. (668 aa)
Cre-rpn-3CRE-RPN-3 protein. (506 aa)
Cre-top-3DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (780 aa)
CRE_01039Mcm10 domain-containing protein. (692 aa)
Cre-mrt-2CRE-MRT-2 protein. (267 aa)
CRE_02382Uncharacterized protein. (213 aa)
CRE_19143Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (320 aa)
CRE_27630Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (320 aa)
CRE_27631Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (301 aa)
Cre-mcm-5DNA helicase; Belongs to the MCM family. (759 aa)
CRE_29915FHA domain-containing protein. (545 aa)
CRE_06764AAA domain-containing protein. (365 aa)
Cre-mdt-30CRE-MDT-30 protein. (537 aa)
CRE_08348Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (442 aa)
Cre-rpn-11CRE-RPN-11 protein. (312 aa)
Cre-mre-11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (722 aa)
Cre-par-5CRE-PAR-5 protein; Belongs to the 14-3-3 family. (248 aa)
CRE_21389Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (295 aa)
CRE_21390Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (288 aa)
CRE_20858Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
CRE_23600AAA domain-containing protein; Belongs to the AAA ATPase family. (329 aa)
CRE_22920Reverse transcriptase domain-containing protein. (294 aa)
CRE_09708Protein kinase domain-containing protein. (525 aa)
CRE_19313Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (448 aa)
CRE_19314Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (458 aa)
CRE_19288Protein kinase domain-containing protein. (423 aa)
Cre-rpn-5CRE-RPN-5 protein. (507 aa)
CRE_27745BLM10_mid domain-containing protein. (816 aa)
CRE_11299Reverse transcriptase domain-containing protein. (943 aa)
CRE_27746DUF3437 domain-containing protein. (1052 aa)
Your Current Organism:
Caenorhabditis remanei
NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris
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