(68 nodes) Glyoxylate and dicarboxylate metabolism network (Caenorhabditis remanei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cre-gei-7	Malate synthase; Belongs to the malate synthase family. (970 aa)
	Cre-pcca-1	CRE-PCCA-1 protein. (726 aa)
	Cre-pccb-1	CRE-PCCB-1 protein. (536 aa)
	Cre-gln-1	CRE-GLN-1 protein; Belongs to the glutamine synthetase family. (385 aa)
	CRE_01880	Serine--pyruvate aminotransferase. (407 aa)
	CRE_18764	FMN hydroxy acid dehydrogenase domain-containing protein. (371 aa)
	CRE_26453	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
	Cre-kat-1	CRE-KAT-1 protein; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
	CRE_26575	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (989 aa)
	Cre-set-27	CRE-SET-27 protein. (501 aa)
	Cre-cts-1	Citrate synthase; Belongs to the citrate synthase family. (479 aa)
	CRE_30811	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa)
	CRE_31065	Uncharacterized protein. (347 aa)
	CRE_30814	Uncharacterized protein. (336 aa)
	CRE_31139	Malate dehydrogenase. (340 aa)
	CRE_03169	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family. (266 aa)
	Cre-mel-32	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
	Cre-mdh-1	Malate dehydrogenase. (356 aa)
	CRE_02813	DUF4147 domain-containing protein. (992 aa)
	CRE_02814	Uncharacterized protein. (291 aa)
	CRE_02815	MOFRL domain-containing protein. (209 aa)
	Cre-set-29	CRE-SET-29 protein. (401 aa)
	Cre-adpr-1	CRE-ADPR-1 protein. (556 aa)
	Cre-aco-1	CRE-ACO-1 protein; Belongs to the aconitase/IPM isomerase family. (903 aa)
	Cre-gln-2	CRE-GLN-2 protein; Belongs to the glutamine synthetase family. (368 aa)
	CRE_10259	Uncharacterized protein. (275 aa)
	CRE_12495	Abhydrolase_3 domain-containing protein. (290 aa)
	CRE_13309	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (368 aa)
	CRE_13414	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (378 aa)
	CRE_13325	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (392 aa)
	Cre-mmcm-1	CRE-MMCM-1 protein. (840 aa)
	CRE_13377	Acetyl-coenzyme A synthetase. (680 aa)
	CRE_15377	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (171 aa)
	CRE_28764	Uncharacterized protein; Belongs to the HAD-like hydrolase superfamily. (303 aa)
	CRE_28685	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (256 aa)
	CRE_28688	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (368 aa)
	CRE_29903	AAA domain-containing protein; Belongs to the AAA ATPase family. (352 aa)
	Cre-ctl-2	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (511 aa)
	Cre-ctl-3	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (521 aa)
	Cre-aco-2	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (777 aa)
	CRE_16895	PNPLA domain-containing protein. (543 aa)
	Cre-tag-241	CRE-TAG-241 protein. (1654 aa)
	CRE_05993	Uncharacterized protein. (71 aa)
	CRE_07729	ATPase_AAA_core domain-containing protein. (597 aa)
	CRE_12139	Uncharacterized protein; Belongs to the HAD-like hydrolase superfamily. (314 aa)
	CRE_12140	NIPSNAP domain-containing protein. (230 aa)
	CRE_24143	Lipoyl-binding domain-containing protein. (260 aa)
	CRE_23640	Aconitase domain-containing protein. (155 aa)
	Cre-gln-3	Glutamine synthetase. (386 aa)
	CRE_11384	Dihydrolipoyl dehydrogenase. (495 aa)
	CRE_23064	Uncharacterized protein. (419 aa)
	Cre-mce-1	CRE-MCE-1 protein. (162 aa)
	CRE_11507	DUF4147 domain-containing protein. (415 aa)
	CRE_30541	Uncharacterized protein; Belongs to the HAD-like hydrolase superfamily. (303 aa)
	CRE_22189	PNPLA domain-containing protein. (543 aa)
	CRE_01451	Uncharacterized protein. (321 aa)
	CRE_01452	Uncharacterized protein. (171 aa)
	CRE_10734	Uncharacterized protein. (479 aa)
	CRE_14423	AAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
	CRE_23826	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (506 aa)
	CRE_17781	Uncharacterized protein. (317 aa)
	CRE_02782	Uncharacterized protein. (280 aa)
	CRE_17786	ACT domain-containing protein. (288 aa)
	CRE_20166	Uncharacterized protein. (207 aa)
	CRE_11637	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (407 aa)
	CRE_29411	Gln_synt_b-grasp domain-containing protein. (176 aa)
	CRE_06283	Thiolase_N domain-containing protein. (274 aa)
	CRE_17723	Uncharacterized protein. (210 aa)

Your Current Organism:

Caenorhabditis remanei

NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRE_01880	CRE_02813	E3LG15	E3LX46	Serine--pyruvate aminotransferase.	DUF4147 domain-containing protein.	0.857
CRE_01880	CRE_02814	E3LG15	E3LX47	Serine--pyruvate aminotransferase.	Uncharacterized protein.	0.857
CRE_01880	CRE_02815	E3LG15	E3LX49	Serine--pyruvate aminotransferase.	MOFRL domain-containing protein.	0.857
CRE_01880	CRE_03169	E3LG15	E3LWX9	Serine--pyruvate aminotransferase.	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	0.921
CRE_01880	CRE_10734	E3LG15	E3NPC5	Serine--pyruvate aminotransferase.	Uncharacterized protein.	0.904
CRE_01880	CRE_11384	E3LG15	E3N753	Serine--pyruvate aminotransferase.	Dihydrolipoyl dehydrogenase.	0.904
CRE_01880	CRE_11507	E3LG15	E3NJJ8	Serine--pyruvate aminotransferase.	DUF4147 domain-containing protein.	0.857
CRE_01880	CRE_11637	E3LG15	E3NVG3	Serine--pyruvate aminotransferase.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.951
CRE_01880	CRE_13377	E3LG15	E3M8H2	Serine--pyruvate aminotransferase.	Acetyl-coenzyme A synthetase.	0.435
CRE_01880	CRE_15377	E3LG15	E3MC04	Serine--pyruvate aminotransferase.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.971
CRE_01880	CRE_18764	E3LG15	E3LK37	Serine--pyruvate aminotransferase.	FMN hydroxy acid dehydrogenase domain-containing protein.	0.978
CRE_01880	CRE_20166	E3LG15	E3NVE7	Serine--pyruvate aminotransferase.	Uncharacterized protein.	0.904
CRE_01880	CRE_23064	E3LG15	E3N9G9	Serine--pyruvate aminotransferase.	Uncharacterized protein.	0.706
CRE_01880	CRE_23640	E3LG15	E3N486	Serine--pyruvate aminotransferase.	Aconitase domain-containing protein.	0.497
CRE_01880	CRE_23826	E3LG15	E3NS56	Serine--pyruvate aminotransferase.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.708
CRE_01880	CRE_24143	E3LG15	E3N466	Serine--pyruvate aminotransferase.	Lipoyl-binding domain-containing protein.	0.915
CRE_01880	CRE_26575	E3LG15	E3LRC8	Serine--pyruvate aminotransferase.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.963
CRE_01880	CRE_28764	E3LG15	E3MJW6	Serine--pyruvate aminotransferase.	Uncharacterized protein; Belongs to the HAD-like hydrolase superfamily.	0.536
CRE_01880	CRE_30541	E3LG15	E3NLT9	Serine--pyruvate aminotransferase.	Uncharacterized protein; Belongs to the HAD-like hydrolase superfamily.	0.536
CRE_01880	CRE_30811	E3LG15	E3LUE4	Serine--pyruvate aminotransferase.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.951