STRINGSTRING
EAR02332.1 EAR02332.1 EAR02384.1 EAR02384.1 EAR02637.1 EAR02637.1 hemH hemH EAR02647.1 EAR02647.1 hemA hemA EAR02649.1 EAR02649.1 hemE hemE EAR02651.1 EAR02651.1 EAR02652.1 EAR02652.1 EAR02654.1 EAR02654.1 EAR02655.1 EAR02655.1 EAR02657.1 EAR02657.1 EAR02702.1 EAR02702.1 hemL hemL EAR01150.1 EAR01150.1 EAR01813.1 EAR01813.1 EAR00833.1 EAR00833.1 EAR00834.1 EAR00834.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EAR02332.1Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (346 aa)
EAR02384.1Coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (462 aa)
EAR02637.1Hypothetical protein. (183 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (343 aa)
EAR02647.1Transcriptional regulator. (297 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (418 aa)
EAR02649.1Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (529 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (342 aa)
EAR02651.1Acetyl transferase. (177 aa)
EAR02652.1Coproporphyrinogen III oxidase. (300 aa)
EAR02654.1Hypothetical protein. (203 aa)
EAR02655.1Predicted epimerase PhzC/PhzF-like protein. (262 aa)
EAR02657.1Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (329 aa)
EAR02702.1Hypothetical protein. (215 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (429 aa)
EAR01150.1Cytochrome c assembly protein. (1063 aa)
EAR01813.1Cytochrome c assembly protein. (1041 aa)
EAR00833.1uroporphyrin-III C-methyltransferase. (193 aa)
EAR00834.1uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (255 aa)
Your Current Organism:
Maribacter sp. HTCC2170
NCBI taxonomy Id: 313603
Other names: Flavobacteriales bacterium HTCC2170, M. sp. HTCC2170
Server load: low (14%) [HD]