STRINGSTRING
nadK nadK EAR00894.1 EAR00894.1 EAR00847.1 EAR00847.1 EAR00842.1 EAR00842.1 EAR00839.1 EAR00839.1 pfkA-2 pfkA-2 lpxK lpxK EAR00707.1 EAR00707.1 EAR00692.1 EAR00692.1 EAR00691.1 EAR00691.1 EAR00677.1 EAR00677.1 EAR00674.1 EAR00674.1 EAR00654.1 EAR00654.1 EAR00637.1 EAR00637.1 EAQ99830.1 EAQ99830.1 EAR02007.1 EAR02007.1 EAR01992.1 EAR01992.1 EAR01990.1 EAR01990.1 EAR01978.1 EAR01978.1 EAR01969.1 EAR01969.1 cmk cmk EAR01898.1 EAR01898.1 thrB thrB EAR01870.1 EAR01870.1 EAR01858.1 EAR01858.1 EAR01848.1 EAR01848.1 EAR01760.1 EAR01760.1 EAR01746.1 EAR01746.1 EAR01723.1 EAR01723.1 EAR01682.1 EAR01682.1 EAR01674.1 EAR01674.1 EAR01673.1 EAR01673.1 EAR01672.1 EAR01672.1 EAR01671.1 EAR01671.1 EAR00417.1 EAR00417.1 coaE coaE EAR00408.1 EAR00408.1 EAR00406.1 EAR00406.1 EAR00385.1 EAR00385.1 EAR00313.1 EAR00313.1 EAR00246.1 EAR00246.1 EAR01433.1 EAR01433.1 EAR01430.1 EAR01430.1 EAR01429.1 EAR01429.1 EAR01428.1 EAR01428.1 EAR01401.1 EAR01401.1 EAR01289.1 EAR01289.1 EAR01161.1 EAR01161.1 EAR01121.1 EAR01121.1 EAR01105.1 EAR01105.1 EAR01071.1 EAR01071.1 pfkA pfkA EAR01046.1 EAR01046.1 EAR01025.1 EAR01025.1 ndk ndk EAR00942.1 EAR00942.1 EAR00626.1 EAR00626.1 EAR00521.1 EAR00521.1 coaX coaX EAR00496.1 EAR00496.1 proB proB argB argB EAR00475.1 EAR00475.1 EAR00474.1 EAR00474.1 EAQ99908.1 EAQ99908.1 EAQ99904.1 EAQ99904.1 EAQ99801.1 EAQ99801.1 EAQ99794.1 EAQ99794.1 EAQ99793.1 EAQ99793.1 EAQ99788.1 EAQ99788.1 glpK glpK EAR02970.1 EAR02970.1 EAR02945.1 EAR02945.1 EAR02933.1 EAR02933.1 EAR02926.1 EAR02926.1 EAR02910.1 EAR02910.1 tdk tdk EAR02829.1 EAR02829.1 pgk pgk EAR02703.1 EAR02703.1 thiL thiL EAR02636.1 EAR02636.1 EAR02622.1 EAR02622.1 gmk gmk cysC cysC EAR02530.1 EAR02530.1 EAR02471.1 EAR02471.1 EAR02454.1 EAR02454.1 EAR02449.1 EAR02449.1 EAR02424.1 EAR02424.1 EAR02389.1 EAR02389.1 EAR02386.1 EAR02386.1 EAR02320.1 EAR02320.1 EAR02319.1 EAR02319.1 pyrH pyrH EAR02194.1 EAR02194.1 EAR02181.1 EAR02181.1 adk adk EAR02024.1 EAR02024.1 EAQ99675.1 EAQ99675.1 EAQ99995.1 EAQ99995.1 EAR00221.1 EAR00221.1 EAR00122.1 EAR00122.1 EAR00083.1 EAR00083.1 ackA ackA aroK aroK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nadKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (293 aa)
EAR00894.1ROK family protein. (286 aa)
EAR00847.1Deoxynucleoside kinase subfamily, putative. (204 aa)
EAR00842.1Bifunctional aspartokinase I/homoserine dehydrogenase I. (1128 aa)
EAR00839.1Hypothetical protein. (86 aa)
pfkA-2Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (444 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (344 aa)
EAR00707.1Multi-sensor hybrid histidine kinase. (728 aa)
EAR00692.1Hypothetical protein. (282 aa)
EAR00691.1Hypothetical protein. (269 aa)
EAR00677.1Histidine kinase sensor protein. (999 aa)
EAR00674.1Hypothetical protein. (195 aa)
EAR00654.1Hypothetical protein. (75 aa)
EAR00637.1Hypothetical protein. (103 aa)
EAQ99830.1Hypothetical protein. (112 aa)
EAR02007.1Pyruvate kinase. (624 aa)
EAR01992.1Two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'). (1356 aa)
EAR01990.1Histidine kinase response regulator hybrid protein. (411 aa)
EAR01978.1Hypothetical protein. (245 aa)
EAR01969.1Hypothetical protein. (312 aa)
cmkCytidylate kinase. (235 aa)
EAR01898.1Putative two-component system sensor protein, no kinase domain. (347 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (307 aa)
EAR01870.1Aspartokinase/homoserine dehydrogenase. (814 aa)
EAR01858.12-dehydro-3-deoxygluconokinase. (346 aa)
EAR01848.1Hypothetical protein. (1009 aa)
EAR01760.1Galactokinase; Belongs to the GHMP kinase family. GalK subfamily. (377 aa)
EAR01746.1Sensory transduction histidine kinase. (411 aa)
EAR01723.1Hypothetical protein. (595 aa)
EAR01682.1Signal transduction histidine kinase. (652 aa)
EAR01674.1Hypothetical protein. (440 aa)
EAR01673.1Hypothetical protein. (107 aa)
EAR01672.1Hypothetical protein. (113 aa)
EAR01671.1Hypothetical protein. (117 aa)
EAR00417.1Conserved hypothetical lipoprotein. (282 aa)
coaEPutative dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (196 aa)
EAR00408.1Two-component system sensor histidine kinase. (526 aa)
EAR00406.1Putative D-gluconate kinase active at low temperature (idonate catabolism). (160 aa)
EAR00385.1Putative transmembrane protein. (702 aa)
EAR00313.1Two-component hybrid sensor and regulator. (657 aa)
EAR00246.1Probable diacylglycerol kinase. (121 aa)
EAR01433.1Listeriolysin O. (688 aa)
EAR01430.1Hypothetical protein. (349 aa)
EAR01429.1Hypothetical protein. (361 aa)
EAR01428.1Hypothetical exported 24-amino acid repeat protein. (184 aa)
EAR01401.1Putative transmembrane sensor histidine kinase transcription regulator protein. (264 aa)
EAR01289.1Two-component system sensory/regulatory protein (hybrid family). (594 aa)
EAR01161.1Sensor histidine kinase/response regulator. (671 aa)
EAR01121.1Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (909 aa)
EAR01105.1Putative tyrosine-protein kinase. (788 aa)
EAR01071.1Hypothetical protein. (283 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (328 aa)
EAR01046.1Hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (356 aa)
EAR01025.1Uridine kinase. (202 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (170 aa)
EAR00942.1Hypothetical protein. (936 aa)
EAR00626.1Ribonuclease HII. (820 aa)
EAR00521.1Hypothetical protein. (302 aa)
coaXPutative regulatory protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (242 aa)
EAR00496.1Hypothetical exported 24-amino acid repeat protein. (160 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (254 aa)
argBPutative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (259 aa)
EAR00475.1Hypothetical protein. (312 aa)
EAR00474.1Diphosphomevalonate decarboxylase. (360 aa)
EAQ99908.1Putative two-component system sensor histidine kinase. (448 aa)
EAQ99904.1Sensor histidine kinase. (334 aa)
EAQ99801.1Sensor histidine kinase. (382 aa)
EAQ99794.1Hypothetical protein. (513 aa)
EAQ99793.1Possible transcriptional regulatory protein nadr. (170 aa)
EAQ99788.1Putative ROK family transcriptional repressor. (320 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (495 aa)
EAR02970.1Fructokinase. (315 aa)
EAR02945.1ROK family member transcriptional repressor. (309 aa)
EAR02933.1Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa)
EAR02926.1Carbohydrate kinase, PfkB family protein. (308 aa)
EAR02910.1Hypothetical protein; Belongs to the glycerate kinase type-1 family. (374 aa)
tdkPutative thymidine kinase. (214 aa)
EAR02829.1Hypothetical protein; Belongs to the fructosamine kinase family. (297 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
EAR02703.1Signaling protein without kinase domain. (323 aa)
thiLPutative thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (349 aa)
EAR02636.1Sensory transduction histidine kinase. (473 aa)
EAR02622.1Putative two-component system sensor histidine kinase. (642 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (197 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (198 aa)
EAR02530.1Multi-sensor hybrid histidine kinase. (511 aa)
EAR02471.1Aspartate kinase III; Belongs to the aspartokinase family. (416 aa)
EAR02454.1Riboflavin kinase / FAD synthetase; Belongs to the ribF family. (308 aa)
EAR02449.1Ribose-phosphate pyrophosphokinase. (313 aa)
EAR02424.1Hypothetical protein. (266 aa)
EAR02389.1Xylulose kinase (xylulokinase). (494 aa)
EAR02386.1Hypothetical protein. (353 aa)
EAR02320.1Multi-sensor signal transduction histidine kinase. (530 aa)
EAR02319.1Hypothetical protein. (106 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (235 aa)
EAR02194.1Histidine kinase. (734 aa)
EAR02181.1Deoxyguanosine kinase/deoxyadenosine kinase subunit. (381 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (368 aa)
EAR02024.1PfkB. (335 aa)
EAQ99675.1ROK family protein. (249 aa)
EAQ99995.1Putative two-component system sensor protein, without kinase domain. (361 aa)
EAR00221.1Hypothetical protein. (304 aa)
EAR00122.1Signal transduction histidine kinase. (404 aa)
EAR00083.1Hypothetical protein. (213 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
aroKPutative shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (163 aa)
Your Current Organism:
Maribacter sp. HTCC2170
NCBI taxonomy Id: 313603
Other names: Flavobacteriales bacterium HTCC2170, M. sp. HTCC2170
Server load: low (32%) [HD]