STRINGSTRING
EAR02341.1 EAR02341.1 EAR02342.1 EAR02342.1 hutU hutU hutG hutG EAR02979.1 EAR02979.1 hisG hisG hisD hisD hisC hisC hisB hisB hisH hisH hisA hisA hisF hisF hisI hisI EAR01511.1 EAR01511.1 EAR01520.1 EAR01520.1 EAR01791.1 EAR01791.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EAR02341.1Histidine ammonia-lyase. (526 aa)
EAR02342.1Imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (415 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (672 aa)
hutGFormiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (315 aa)
EAR02979.1Piperideine-6-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (517 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (347 aa)
hisBImidazole glycerol-phosphate dehydratase/histidinol phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (377 aa)
hisHImidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (193 aa)
hisAPhosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. (244 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (242 aa)
hisIHistidine biosynthesis bifunctional protein; In the N-terminal section; belongs to the PRA-CH family. (200 aa)
EAR01511.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (454 aa)
EAR01520.1Histidinol-phosphate aminotransferase. (371 aa)
EAR01791.1Flavin-containing amine oxidase. (479 aa)
Your Current Organism:
Maribacter sp. HTCC2170
NCBI taxonomy Id: 313603
Other names: Flavobacteriales bacterium HTCC2170, M. sp. HTCC2170
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