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NSP_25300 NSP_25300 NSP_25290 NSP_25290 NSP_20010 NSP_20010 NSP_19560 NSP_19560 mraY mraY ftsZ ftsZ NSP_5010 NSP_5010 NSP_13210 NSP_13210 ftsE ftsE NSP_5490 NSP_5490 murF murF smc smc NSP_9180 NSP_9180 murD murD NSP_4950 NSP_4950 tig tig NSP_48300 NSP_48300 murB murB murC murC NSP_4150 NSP_4150 NSP_4140 NSP_4140 murG murG NSP_3440 NSP_3440 sepF sepF NSP_31800 NSP_31800 murA murA NSP_31190 NSP_31190 minC minC NSP_27710 NSP_27710 NSP_27700 NSP_27700 murE murE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NSP_25300Hypothetical protein; Nsp25300; ORF_ID:nsp25300. (479 aa)
NSP_25290Hypothetical protein; Nsp25290; ORF_ID:nsp25290. (493 aa)
NSP_20010Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (179 aa)
NSP_19560Cell division initiation protein; Nsp19560; ORF_ID:nsp19560. (172 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (370 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (380 aa)
NSP_5010Hypothetical protein; Nsp5010; ORF_ID:nsp5010. (240 aa)
NSP_13210Hypothetical protein; Nsp13210; ORF_ID:nsp13210. (338 aa)
ftsECell division transporter, ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (255 aa)
NSP_5490HlyD family secretion protein; Nsp5490; ORF_ID:nsp5490. (500 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (450 aa)
smcChromosome partition protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1206 aa)
NSP_9180Chromosome segregation ATPase; Nsp9180; ORF_ID:nsp9180. (691 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (455 aa)
NSP_4950Hypothetical protein; Nsp4950; ORF_ID:nsp4950. (142 aa)
tigCell division trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (473 aa)
NSP_48300Myosin heavy chain; Nsp48300; ORF_ID:nsp48300. (415 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (340 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (495 aa)
NSP_4150Periplasmic component of the Tol biopolymer transport system; Nsp4150; ORF_ID:nsp4150. (108 aa)
NSP_4140Periplasmic component of the Tol biopolymer transport system; Nsp4140; ORF_ID:nsp4140. (181 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (359 aa)
NSP_3440Chromosome segregation SMC protein; Nsp3440; ORF_ID:nsp3440. (219 aa)
sepFHypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (202 aa)
NSP_31800Hypothetical protein; Nsp31800; ORF_ID:nsp31800. (371 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (439 aa)
NSP_31190Cell division protein FtsX; Nsp31190; ORF_ID:nsp31190; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (300 aa)
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (345 aa)
NSP_27710Septum site-determining protein MinD; Nsp27710; ORF_ID:nsp27710. (268 aa)
NSP_27700Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (76 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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