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murJ murJ murD murD NSP_15990 NSP_15990 mraY mraY uppP uppP NSP_23020 NSP_23020 murE murE glmU glmU NSP_31360 NSP_31360 NSP_31380 NSP_31380 murA murA NSP_31910 NSP_31910 ddl ddl NSP_35940 NSP_35940 NSP_38640 NSP_38640 murG murG murI murI murC murC murB murB murF murF NSP_8210 NSP_8210
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murJHypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (534 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (455 aa)
NSP_15990Hypothetical protein; Nsp15990; ORF_ID:nsp15990. (237 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (370 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (321 aa)
NSP_23020D-alanine--D-alanine ligase; Nsp23020; ORF_ID:nsp23020. (350 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
glmUN-acetylglucosamine-1-phosphate uridyltransferase / Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (455 aa)
NSP_31360Putative amino acid ligase found clustered with an amidotransferase; Nsp31360; ORF_ID:nsp31360. (429 aa)
NSP_31380Putative amidotransferase similar to cobyric acid synthase; Nsp31380; ORF_ID:nsp31380. (272 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (439 aa)
NSP_31910Cell division protein FtsI [Peptidoglycan synthetase]; Nsp31910; ORF_ID:nsp31910. (602 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (355 aa)
NSP_35940Bacterial cell division membrane protein; Nsp35940; ORF_ID:nsp35940; Belongs to the SEDS family. (345 aa)
NSP_38640Cyanophycin synthase; Nsp38640; ORF_ID:nsp38640. (636 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (359 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (297 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (495 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (340 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (450 aa)
NSP_8210KH domain RNA binding protein YlqC; Nsp8210; ORF_ID:nsp8210. (146 aa)
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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