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rimO rimO NSP_20230 NSP_20230 NSP_24790 NSP_24790 NSP_24880 NSP_24880 NSP_25640 NSP_25640 mnmE mnmE rsmI rsmI fmt fmt mnmG mnmG NSP_29180 NSP_29180 mnmA mnmA NSP_3190 NSP_3190 NSP_32360 NSP_32360 NSP_35890 NSP_35890 NSP_36070 NSP_36070 trmB trmB rsmA rsmA tgt tgt NSP_39190 NSP_39190 trmFO trmFO tsaD tsaD NSP_41470 NSP_41470 tilS tilS truA truA NSP_44620 NSP_44620 NSP_45970 NSP_45970 rsmH rsmH NSP_46710 NSP_46710 NSP_47970 NSP_47970 NSP_49670 NSP_49670 NSP_49770 NSP_49770 rlmN rlmN NSP_52160 NSP_52160 NSP_52800 NSP_52800 NSP_7670 NSP_7670 rsmG rsmG NSP_8900 NSP_8900 NSP_9740 NSP_9740 trmD trmD tadA tadA NSP_17760 NSP_17760 NSP_16110 NSP_16110 truB truB miaB miaB NSP_14060 NSP_14060 trmJ trmJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rimORibosomal protein S12p Asp88 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (442 aa)
NSP_20230tRNA dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (339 aa)
NSP_24790Sun/nucleolar protein family protein; Nsp24790; ORF_ID:nsp24790; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (326 aa)
NSP_24880Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (309 aa)
NSP_25640tRNA pseudouridine synthase A; Nsp25640; ORF_ID:nsp25640; Belongs to the pseudouridine synthase RsuA family. (208 aa)
mnmEGTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (463 aa)
rsmIrRNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (288 aa)
fmtMethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (333 aa)
mnmGtRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (640 aa)
NSP_29180Hypothetical protein; Nsp29180; ORF_ID:nsp29180. (376 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (351 aa)
NSP_3190rRNA methylase; Nsp3190; ORF_ID:nsp3190; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (261 aa)
NSP_32360Hypothetical protein; Nsp32360; ORF_ID:nsp32360. (480 aa)
NSP_35890RRNA methylase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (153 aa)
NSP_36070O-methyltransferase, family 2; Nsp36070; ORF_ID:nsp36070. (336 aa)
trmBtRNA(m7G46)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (215 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (275 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (332 aa)
NSP_39190TrmH family tRNA/rRNA methyltransferase YacO; Nsp39190; ORF_ID:nsp39190; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (323 aa)
trmFOtRNA:m(5)U-54 MTase gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (437 aa)
tsaDYgjD/Kae1/Qri7 family, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (345 aa)
NSP_41470tRNA dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (350 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (333 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (296 aa)
NSP_44620Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (449 aa)
NSP_45970Small GTP-binding protein domain; Nsp45970; ORF_ID:nsp45970. (517 aa)
rsmHrRNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (302 aa)
NSP_46710Metal-dependent proteases-like, putative molecular chaperone; Nsp46710; ORF_ID:nsp46710. (219 aa)
NSP_47970ATPase YjeE, predicted to have essential role in cell wall biosynthesis; Nsp47970; ORF_ID:nsp47970. (163 aa)
NSP_49670Ribosomal large subunit pseudouridine synthase A; Nsp49670; ORF_ID:nsp49670. (550 aa)
NSP_49770Small GTP-binding protein domain precursor; Nsp49770; ORF_ID:nsp49770. (638 aa)
rlmNRibosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (352 aa)
NSP_52160RNA methyltransferase, TrmA family; Nsp52160; ORF_ID:nsp52160; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (468 aa)
NSP_52800Cytosine deaminase; Nsp52800; ORF_ID:nsp52800. (143 aa)
NSP_7670Hypothetical protein; Nsp7670; ORF_ID:nsp7670; Belongs to the sulfur carrier protein TusA family. (85 aa)
rsmGrRNA small subunit methyltransferase, glucose inhibited division protein GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (246 aa)
NSP_8900Rhodanese domain protein UPF0176, cyanobacterial/alphaproteobacterial subgroup; Nsp8900; ORF_ID:nsp8900; Belongs to the UPF0176 family. (298 aa)
NSP_9740Ribosomal small subunit pseudouridine synthase A; Nsp9740; ORF_ID:nsp9740; Belongs to the pseudouridine synthase RsuA family. (264 aa)
trmDtRNA (Guanine37-N1) -methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (235 aa)
tadAtRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (164 aa)
NSP_17760Ribosomal RNA small subunit methyltransferase D; Nsp17760; ORF_ID:nsp17760. (182 aa)
NSP_16110Small GTP-binding protein domain; Nsp16110; ORF_ID:nsp16110. (449 aa)
truBtRNA pseudouridine synthase B tRNA Psi55; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (290 aa)
miaBtRNA-i(6)A37 methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (454 aa)
NSP_14060Hypothetical protein; Nsp14060; ORF_ID:nsp14060. (442 aa)
trmJtRNA:Cm32/Um32 methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (245 aa)
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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