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| | argD | Acetylornithine aminotransferase; Nsp46650; ORF_ID:nsp46650; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (440 aa) |
| | NSP_10510 | Ferredoxin-dependent glutamate synthase; Nsp10510; ORF_ID:nsp10510. (1567 aa) |
| | pheA | Prephenate dehydratase; Nsp10640; ORF_ID:nsp10640. (291 aa) |
| | NSP_11580 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1184 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (271 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | argG | Argininosuccinate synthase; Nsp12880; ORF_ID:nsp12880; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa) |
| | NSP_13050 | UDP-glucose dehydrogenase; Nsp13050; ORF_ID:nsp13050. (463 aa) |
| | NSP_13640 | Omega-3 polyunsaturated fatty acid synthase subunit, PfaB; Nsp13640; ORF_ID:nsp13640; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (1085 aa) |
| | NSP_13650 | Heterocyst glycolipid synthase; Nsp13650; ORF_ID:nsp13650. (2330 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (251 aa) |
| | NSP_1450 | Acetolactate synthase large subunit; Nsp1450; ORF_ID:nsp1450. (632 aa) |
| | NSP_14900 | Cysteine synthase B; Nsp14900; ORF_ID:nsp14900. (325 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Nsp1510; ORF_ID:nsp1510; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (382 aa) |
| | NSP_15130 | Ferredoxin oxidoreductase; Nsp15130; ORF_ID:nsp15130. (389 aa) |
| | NSP_16180 | Glutamine synthetase type I; Nsp16180; ORF_ID:nsp16180. (471 aa) |
| | argJ | Glutamate N-acetyltransferase / N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (430 aa) |
| | hisH | Imidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Nsp18000; ORF_ID:nsp18000. (256 aa) |
| | NSP_18840 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (363 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa) |
| | NSP_20100 | Bifunctional protein: zinc-containing alcohol dehydrogenase; Nsp20100; ORF_ID:nsp20100. (335 aa) |
| | NSP_20200 | Acetolactate synthase small subunit; Nsp20200; ORF_ID:nsp20200. (172 aa) |
| | NSP_20430 | Glutamate dehydrogenase/leucine dehydrogenase; Nsp20430; ORF_ID:nsp20430. (334 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Nsp20990; ORF_ID:nsp20990; In the N-terminal section; belongs to the PRA-CH family. (225 aa) |
| | dapL | L,L-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (411 aa) |
| | acpP-2 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (85 aa) |
| | NSP_21280 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (416 aa) |
| | NSP_21400 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (300 aa) |
| | NSP_2330 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (310 aa) |
| | mtnP | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (291 aa) |
| | NSP_23830 | Fe-S oxidoreductases of moaA/nifB/pqqE family; Nsp23830; ORF_ID:nsp23830. (337 aa) |
| | NSP_25260 | (R)-citramalate synthase; Nsp25260; ORF_ID:nsp25260; Belongs to the alpha-IPM synthase/homocitrate synthase family. (543 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (296 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (256 aa) |
| | NSP_26330 | 2-dehydropantoate 2-reductase; Nsp26330; ORF_ID:nsp26330. (326 aa) |
| | NSP_26340 | D-3-phosphoglycerate dehydrogenase; Nsp26340; ORF_ID:nsp26340; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa) |
| | ilvA | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (490 aa) |
| | NSP_2650 | Enoyl-[acyl-carrier-protein] reductase [NADH]; Nsp2650; ORF_ID:nsp2650. (258 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Nsp2660; ORF_ID:nsp2660. (207 aa) |
| | NSP_26710 | Malonyl CoA-acyl carrier protein transacylase; Nsp26710; ORF_ID:nsp26710. (2478 aa) |
| | NSP_26720 | Malonyl CoA-acyl carrier protein transacylase; Nsp26720; ORF_ID:nsp26720. (2471 aa) |
| | NSP_26940 | Malonyl CoA-acyl carrier protein transacylase; Nsp26940; ORF_ID:nsp26940. (1505 aa) |
| | NSP_27060 | Malonyl CoA-acyl carrier protein transacylase; Nsp27060; ORF_ID:nsp27060. (1584 aa) |
| | NSP_28440 | N-acetyl-L,L-diaminopimelate deacetylase-like protein; Nsp28440; ORF_ID:nsp28440. (399 aa) |
| | plsX | Phosphate:acyl-ACP acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (329 aa) |
| | fabH | 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (330 aa) |
| | NSP_29240 | Malonyl CoA-acyl carrier protein transacylase; Nsp29240; ORF_ID:nsp29240. (293 aa) |
| | NSP_29640 | Gluconolactonase; Nsp29640; ORF_ID:nsp29640. (293 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa) |
| | NSP_29770 | Hypothetical protein; Nsp29770; ORF_ID:nsp29770. (47 aa) |
| | NSP_29790 | Anthranilate phosphoribosyltransferase; Nsp29790; ORF_ID:nsp29790. (68 aa) |
| | NSP_3040 | Acetyl-coenzyme A carboxyl transferase alpha chain; Nsp3040; ORF_ID:nsp3040. (178 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (455 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (224 aa) |
| | panC/cmk | Pantoate--beta-alanine ligase / Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. (534 aa) |
| | NSP_32720 | Threonine synthase; Nsp32720; ORF_ID:nsp32720. (434 aa) |
| | NSP_32750 | N-acetyl-L,L-diaminopimelate deacetylase-like protein; Nsp32750; ORF_ID:nsp32750. (216 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (336 aa) |
| | hisF | Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | NSP_33480 | N-succinyl-L,L-diaminopimelate aminotransferase alternative; Nsp33480; ORF_ID:nsp33480. (403 aa) |
| | hisG | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (215 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Nsp33730; ORF_ID:nsp33730; Belongs to the IlvD/Edd family. (568 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (324 aa) |
| | NSP_35820 | Homoserine dehydrogenase; Nsp35820; ORF_ID:nsp35820. (428 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (372 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Nsp36740; ORF_ID:nsp36740; Belongs to the TrpC family. (279 aa) |
| | aroE | Shikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (294 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa) |
| | NSP_38210 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (184 aa) |
| | NSP_38450 | Histone acetyltransferase HPA2 and acetyltransferase; Nsp38450; ORF_ID:nsp38450. (162 aa) |
| | NSP_38630 | 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (347 aa) |
| | NSP_38740 | Arogenate dehydrogenase; Nsp38740; ORF_ID:nsp38740. (279 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (426 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Nsp39230; ORF_ID:nsp39230; Belongs to the CarA family. (368 aa) |
| | trpC-2 | Indole-3-glycerol phosphate synthase; Nsp39380; ORF_ID:nsp39380; Belongs to the TrpC family. (428 aa) |
| | NSP_39400 | Serine--glyoxylate aminotransferase; Nsp39400; ORF_ID:nsp39400. (384 aa) |
| | NSP_39600 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (395 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (278 aa) |
| | NSP_39740 | ABC-type phosphate transport system, permease component; Nsp39740; ORF_ID:nsp39740. (176 aa) |
| | NSP_40570 | Serine acetyltransferase; Nsp40570; ORF_ID:nsp40570. (250 aa) |
| | NSP_40640 | Bifunctional protein: zinc-containing alcohol dehydrogenase; Nsp40640; ORF_ID:nsp40640. (315 aa) |
| | NSP_41330 | Cysteine synthase; Nsp41330; ORF_ID:nsp41330; Belongs to the cysteine synthase/cystathionine beta- synthase family. (319 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (413 aa) |
| | NSP_41720 | N-acyl-L-amino acid amidohydrolase; Nsp41720; ORF_ID:nsp41720. (391 aa) |
| | aroA | 5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (450 aa) |
| | NSP_4190 | Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | NSP_42030 | N-acetyl-L,L-diaminopimelate deacetylase-like protein; Nsp42030; ORF_ID:nsp42030. (410 aa) |
| | NSP_42050 | Serine acetyltransferase; Nsp42050; ORF_ID:nsp42050. (229 aa) |
| | NSP_4210 | Hypothetical protein; Nsp4210; ORF_ID:nsp4210. (200 aa) |
| | NSP_42150 | Malonyl CoA-acyl carrier protein transacylase; Nsp42150; ORF_ID:nsp42150. (2640 aa) |
| | NSP_42160 | Malonyl CoA-acyl carrier protein transacylase; Nsp42160; ORF_ID:nsp42160. (3873 aa) |
| | NSP_42180 | Malonyl CoA-acyl carrier protein transacylase; Nsp42180; ORF_ID:nsp42180. (3475 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (362 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (435 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa) |
| | NSP_42420 | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (202 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (369 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (534 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (403 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (362 aa) |
| | accD | Acetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (316 aa) |
| | NSP_43390 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (320 aa) |
| | fabZ | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (169 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (305 aa) |
| | NSP_44730 | Phosphatidylcholine desaturase; Nsp44730; ORF_ID:nsp44730. (374 aa) |
| | proA-2 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa) |
| | lipA-2 | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (306 aa) |
| | aroQ | 3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (152 aa) |
| | hisC-2 | Histidinol-phosphate aminotransferase; Nsp45900; ORF_ID:nsp45900; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa) |
| | NSP_46080 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Nsp46080; ORF_ID:nsp46080. (176 aa) |
| | NSP_46310 | Omega-3 polyunsaturated fatty acid synthase subunit, PfaB; Nsp46310; ORF_ID:nsp46310; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (1556 aa) |
| | NSP_46330 | Hypothetical protein; Nsp46330; ORF_ID:nsp46330. (572 aa) |
| | NSP_46340 | Heterocyst glycolipid synthase; Nsp46340; ORF_ID:nsp46340. (1697 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (279 aa) |
| | NSP_47210 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (473 aa) |
| | NSP_48090 | Cobalamin biosynthesis protein CobG; Nsp48090; ORF_ID:nsp48090; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (494 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (349 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | NSP_49130 | 3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | proC-2 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (271 aa) |
| | NSP_49300 | 3-isopropylmalate dehydrogenase; Nsp49300; ORF_ID:nsp49300. (363 aa) |
| | NSP_49310 | 3-isopropylmalate dehydratase large subunit; Nsp49310; ORF_ID:nsp49310; Belongs to the aconitase/IPM isomerase family. (574 aa) |
| | NSP_50060 | Asparagine synthetase [glutamine-hydrolyzing]; Nsp50060; ORF_ID:nsp50060. (643 aa) |
| | NSP_50550 | Bacilysin biosynthesis protein bacA; Nsp50550; ORF_ID:nsp50550. (193 aa) |
| | NSP_51690 | Chorismate mutase II; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (137 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (365 aa) |
| | trpB-2 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (425 aa) |
| | trpA-2 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (274 aa) |
| | trpC-3 | Indole-3-glycerol phosphate synthase; Nsp52400; ORF_ID:nsp52400; Belongs to the TrpC family. (275 aa) |
| | NSP_52440 | 3-dehydroquinate synthase; Nsp52440; ORF_ID:nsp52440. (402 aa) |
| | NSP_52460 | Cyclohexadienyl dehydrogenase; Nsp52460; ORF_ID:nsp52460. (297 aa) |
| | NSP_52530 | Hypothetical protein; Nsp52530; ORF_ID:nsp52530. (439 aa) |
| | NSP_52540 | Hypothetical protein; Nsp52540; ORF_ID:nsp52540. (419 aa) |
| | NSP_52570 | Thiamine pyrophosphate-requiring enzymes; Nsp52570; ORF_ID:nsp52570; Belongs to the TPP enzyme family. (627 aa) |
| | NSP_52820 | NAD-specific glutamate dehydrogenase; Nsp52820; ORF_ID:nsp52820; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (429 aa) |
| | NSP_52910 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Nsp52910; ORF_ID:nsp52910; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (429 aa) |
| | aroK | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (192 aa) |
| | NSP_53240 | Serine/threonine protein kinase; Nsp53240; ORF_ID:nsp53240. (456 aa) |
| | NSP_6920 | Asparagine synthetase [glutamine-hydrolyzing]; Nsp6920; ORF_ID:nsp6920. (476 aa) |
| | NSP_7170 | Pterin-binding family; Nsp7170; ORF_ID:nsp7170. (127 aa) |
| | NSP_7260 | Acetylornithine aminotransferase; Nsp7260; ORF_ID:nsp7260. (346 aa) |
| | accA | Acetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Nsp7300; ORF_ID:nsp7300; Belongs to the TrpF family. (211 aa) |
| | mtnA | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (347 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa) |
| | NSP_8770 | Aspartokinase; Nsp8770; ORF_ID:nsp8770. (613 aa) |
| | NSP_9000 | Cysteine synthase; Nsp9000; ORF_ID:nsp9000; Belongs to the cysteine synthase/cystathionine beta- synthase family. (320 aa) |
| | hisD-2 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (433 aa) |
| | argH | Argininosuccinate lyase; Nsp9570; ORF_ID:nsp9570. (461 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Nsp9830; ORF_ID:nsp9830; Belongs to the CarB family. (1088 aa) |
