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mraY mraY minC minC NSP_27710 NSP_27710 NSP_27700 NSP_27700 murE murE NSP_25300 NSP_25300 NSP_23950 NSP_23950 NSP_20010 NSP_20010 NSP_19560 NSP_19560 NSP_17120 NSP_17120 ftsZ ftsZ NSP_14330 NSP_14330 murD murD ftsE ftsE NSP_31180 NSP_31180 NSP_31190 NSP_31190 murA murA sepF sepF NSP_35940 NSP_35940 NSP_37160 NSP_37160 murG murG NSP_4140 NSP_4140 NSP_4150 NSP_4150 NSP_4180 NSP_4180 NSP_44100 NSP_44100 murC murC murB murB tig tig NSP_5010 NSP_5010 murF murF NSP_640 NSP_640 NSP_7220 NSP_7220
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (370 aa)
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (345 aa)
NSP_27710Septum site-determining protein MinD; Nsp27710; ORF_ID:nsp27710. (268 aa)
NSP_27700Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (76 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
NSP_25300Hypothetical protein; Nsp25300; ORF_ID:nsp25300. (479 aa)
NSP_23950Cell division protein FtsW; Nsp23950; ORF_ID:nsp23950; Belongs to the SEDS family. (398 aa)
NSP_20010Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (179 aa)
NSP_19560Cell division initiation protein; Nsp19560; ORF_ID:nsp19560. (172 aa)
NSP_17120Cell division protein FtsK; Nsp17120; ORF_ID:nsp17120. (871 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (380 aa)
NSP_14330Cell division protein FtsQ; Nsp14330; ORF_ID:nsp14330. (273 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (455 aa)
ftsECell division transporter, ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (255 aa)
NSP_31180Hypothetical protein; Nsp31180; ORF_ID:nsp31180. (268 aa)
NSP_31190Cell division protein FtsX; Nsp31190; ORF_ID:nsp31190; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (300 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (439 aa)
sepFHypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (202 aa)
NSP_35940Bacterial cell division membrane protein; Nsp35940; ORF_ID:nsp35940; Belongs to the SEDS family. (345 aa)
NSP_37160Cell division protein YlmG/Ycf19 (putative), YggT family; Nsp37160; ORF_ID:nsp37160. (92 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (359 aa)
NSP_4140Periplasmic component of the Tol biopolymer transport system; Nsp4140; ORF_ID:nsp4140. (181 aa)
NSP_4150Periplasmic component of the Tol biopolymer transport system; Nsp4150; ORF_ID:nsp4150. (108 aa)
NSP_4180YggT family protein YlmG; Nsp4180; ORF_ID:nsp4180; required for proper distribution of nucleoids in chloroplast and cyanobacteria. (97 aa)
NSP_44100Hypothetical protein; Nsp44100; ORF_ID:nsp44100. (485 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (495 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (340 aa)
tigCell division trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (473 aa)
NSP_5010Hypothetical protein; Nsp5010; ORF_ID:nsp5010. (240 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (450 aa)
NSP_640Cell division inhibitor; Nsp640; ORF_ID:nsp640. (306 aa)
NSP_7220Hypothetical protein; Nsp7220; ORF_ID:nsp7220. (158 aa)
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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