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NSP_18880 NSP_18880 comB comB NSP_12590 NSP_12590 glyA glyA NSP_13240 NSP_13240 NSP_13250 NSP_13250 cofG cofG NSP_16630 NSP_16630 NSP_16980 NSP_16980 NSP_18160 NSP_18160 NSP_18330 NSP_18330 mdh mdh fbp fbp NSP_11260 NSP_11260 cofH cofH NSP_39170 NSP_39170 eno eno NSP_37870 NSP_37870 ackA ackA NSP_35360 NSP_35360 ppc ppc NSP_33740 NSP_33740 NSP_33040 NSP_33040 NSP_32910 NSP_32910 gpmI gpmI NSP_28070 NSP_28070 pfkA pfkA NSP_27550 NSP_27550 NSP_26340 NSP_26340 acsA acsA NSP_21780 NSP_21780 NSP_2100 NSP_2100 NSP_40980 NSP_40980 NSP_45370 NSP_45370 NSP_45380 NSP_45380 NSP_47640 NSP_47640 NSP_47910 NSP_47910 NSP_47980 NSP_47980 NSP_4850 NSP_4850 NSP_49890 NSP_49890 NSP_50220 NSP_50220 NSP_590 NSP_590 NSP_5820 NSP_5820 NSP_52750 NSP_52750 NSP_51740 NSP_51740 NSP_50890 NSP_50890 NSP_5080 NSP_5080 NSP_11270 NSP_11270
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NSP_18880Hypothetical protein; Nsp18880; ORF_ID:nsp18880. (207 aa)
comB2-phosphosulfolactate phosphatase; Nsp11390; ORF_ID:nsp11390; Belongs to the ComB family. (234 aa)
NSP_12590Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (816 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
NSP_13240S-(hydroxymethyl)glutathione dehydrogenase; Nsp13240; ORF_ID:nsp13240; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
NSP_13250S-formylglutathione hydrolase; Nsp13250; ORF_ID:nsp13250. (148 aa)
cofG7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (329 aa)
NSP_16630Hypothetical protein; Nsp16630; ORF_ID:nsp16630. (207 aa)
NSP_16980Hypothetical protein; Nsp16980; ORF_ID:nsp16980. (169 aa)
NSP_18160Fructose-1,6-bisphosphatase, GlpX type / Sedoheptulose-1,7-bisphosphatase; Nsp18160; ORF_ID:nsp18160; Belongs to the FBPase class 2 family. (346 aa)
NSP_18330Malate dehydrogenase; Nsp18330; ORF_ID:nsp18330. (117 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (318 aa)
fbpFructose-1,6-bisphosphatase, type I; Nsp50460; ORF_ID:nsp50460; Belongs to the FBPase class 1 family. (349 aa)
NSP_11260Hypothetical protein; Nsp11260; ORF_ID:nsp11260. (71 aa)
cofH7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (380 aa)
NSP_39170Fructose-bisphosphate aldolase class I; Nsp39170; ORF_ID:nsp39170. (360 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
NSP_37870Phosphoenolpyruvate synthase; Nsp37870; ORF_ID:nsp37870. (57 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (406 aa)
NSP_35360Hypothetical protein; Nsp35360; ORF_ID:nsp35360. (207 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1034 aa)
NSP_33740ISSoc2, resolvase; Nsp33740; ORF_ID:nsp33740. (115 aa)
NSP_33040Hypothetical protein; Nsp33040; ORF_ID:nsp33040. (216 aa)
NSP_32910Phosphoenolpyruvate synthase; Nsp32910; ORF_ID:nsp32910. (963 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (532 aa)
NSP_28070NADH-reducing hydrogenase maturation factor; Nsp28070; ORF_ID:nsp28070. (149 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (359 aa)
NSP_27550Hypothetical protein; Nsp27550; ORF_ID:nsp27550. (216 aa)
NSP_26340D-3-phosphoglycerate dehydrogenase; Nsp26340; ORF_ID:nsp26340; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (656 aa)
NSP_21780Phosphoglycerate mutase; Nsp21780; ORF_ID:nsp21780; Belongs to the phosphoglycerate mutase family. (450 aa)
NSP_2100Hypothetical protein; Nsp2100; ORF_ID:nsp2100. (207 aa)
NSP_40980Ni,Fe-hydrogenase maturation factor; Nsp40980; ORF_ID:nsp40980. (155 aa)
NSP_45370Hypothetical protein; Nsp45370; ORF_ID:nsp45370. (71 aa)
NSP_45380Hypothetical protein; Nsp45380; ORF_ID:nsp45380. (71 aa)
NSP_47640Hypothetical protein; Nsp47640; ORF_ID:nsp47640. (216 aa)
NSP_47910Light dependent period modulator LdpA; Nsp47910; ORF_ID:nsp47910. (329 aa)
NSP_47980Hypothetical protein UPF0052; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (462 aa)
NSP_4850Hypothetical protein; Nsp4850; ORF_ID:nsp4850. (201 aa)
NSP_49890Hypothetical protein; Nsp49890; ORF_ID:nsp49890. (115 aa)
NSP_50220Hypothetical protein; Nsp50220; ORF_ID:nsp50220. (207 aa)
NSP_590Hypothetical protein; Nsp590; ORF_ID:nsp590. (547 aa)
NSP_5820Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa)
NSP_52750Phosphoenolpyruvate synthase; Nsp52750; ORF_ID:nsp52750. (784 aa)
NSP_51740Hypothetical protein; Nsp51740; ORF_ID:nsp51740. (71 aa)
NSP_50890Hypothetical protein; Nsp50890; ORF_ID:nsp50890. (207 aa)
NSP_5080BioD-like N-terminal domain of phosphotransacetylase; Nsp5080; ORF_ID:nsp5080. (364 aa)
NSP_11270Hypothetical protein; Nsp11270; ORF_ID:nsp11270. (98 aa)
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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