STRINGSTRING
ruvC ruvC polA polA recG recG NSP_14960 NSP_14960 NSP_17500 NSP_17500 NSP_18930 NSP_18930 NSP_19010 NSP_19010 NSP_19350 NSP_19350 priA priA NSP_20 NSP_20 NSP_20170 NSP_20170 NSP_20470 NSP_20470 recA recA NSP_9160 NSP_9160 ruvA ruvA NSP_22320 NSP_22320 NSP_27460 NSP_27460 NSP_30280 NSP_30280 NSP_30300 NSP_30300 NSP_31240 NSP_31240 recO recO ruvB ruvB NSP_34190 NSP_34190 NSP_36410 NSP_36410 NSP_39870 NSP_39870 NSP_40530 NSP_40530 NSP_4110 NSP_4110 dnaX dnaX NSP_45290 NSP_45290 NSP_46920 NSP_46920 NSP_5510 NSP_5510 recR recR NSP_53100 NSP_53100 recF recF NSP_52670 NSP_52670 NSP_50770 NSP_50770 NSP_49900 NSP_49900 NSP_8450 NSP_8450 NSP_7800 NSP_7800 NSP_6450 NSP_6450 NSP_47600 NSP_47600
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (163 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (972 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (823 aa)
NSP_14960Single-stranded DNA-binding protein; Nsp14960; ORF_ID:nsp14960. (178 aa)
NSP_17500RNA-binding protein; Nsp17500; ORF_ID:nsp17500. (51 aa)
NSP_18930DNA polymerase III delta prime subunit; Nsp18930; ORF_ID:nsp18930. (317 aa)
NSP_19010RNA-binding protein; Nsp19010; ORF_ID:nsp19010. (102 aa)
NSP_19350Amino-terminal intein-mediated trans-splice / DNA polymerase III alpha subunit; Nsp19350; ORF_ID:nsp19350. (448 aa)
priAHelicase PriA essential for oriC/DnaA-independent DNA replication; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (867 aa)
NSP_20DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (387 aa)
NSP_20170Hypothetical protein; Nsp20170; ORF_ID:nsp20170. (259 aa)
NSP_20470Hypothetical protein; Nsp20470; ORF_ID:nsp20470. (487 aa)
recARecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (356 aa)
NSP_9160Hypothetical protein; Nsp9160; ORF_ID:nsp9160. (100 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (213 aa)
NSP_22320Putative DNA polymerase III, epsilon subunit; Nsp22320; ORF_ID:nsp22320. (230 aa)
NSP_27460Single-stranded-DNA-specific exonuclease RecJ; Nsp27460; ORF_ID:nsp27460. (727 aa)
NSP_30280Single-stranded DNA-binding protein; Nsp30280; ORF_ID:nsp30280. (127 aa)
NSP_30300DNA polymerase III delta prime subunit; Nsp30300; ORF_ID:nsp30300. (197 aa)
NSP_31240Single-stranded-DNA-specific exonuclease RecJ; Nsp31240; ORF_ID:nsp31240. (780 aa)
recODNA recombination and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (295 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (367 aa)
NSP_34190Hypothetical protein; Nsp34190; ORF_ID:nsp34190. (480 aa)
NSP_36410Hypothetical protein; Nsp36410; ORF_ID:nsp36410. (250 aa)
NSP_39870Single-stranded DNA-binding protein; Nsp39870; ORF_ID:nsp39870. (120 aa)
NSP_40530NifZ protein; Nsp40530; ORF_ID:nsp40530. (88 aa)
NSP_4110Transcriptional regulator AbrB; Nsp4110; ORF_ID:nsp4110. (143 aa)
dnaXDNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (650 aa)
NSP_45290DNA polymerase III alpha subunit / Carboxy-terminal intein-mediated trans-splice; Nsp45290; ORF_ID:nsp45290. (876 aa)
NSP_46920DNA polymerase III delta subunit; Nsp46920; ORF_ID:nsp46920. (331 aa)
NSP_5510Parvulin-like peptidyl-prolyl isomerase; Nsp5510; ORF_ID:nsp5510. (248 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (185 aa)
NSP_53100RNA-binding protein; Nsp53100; ORF_ID:nsp53100. (106 aa)
recFDNA recombination and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (376 aa)
NSP_52670Hypothetical protein; Nsp52670; ORF_ID:nsp52670. (285 aa)
NSP_50770RNA-binding protein; Nsp50770; ORF_ID:nsp50770. (165 aa)
NSP_49900Regulators of stationary/sporulation gene expression; Nsp49900; ORF_ID:nsp49900. (50 aa)
NSP_8450Parvulin-like peptidyl-prolyl isomerase; Nsp8450; ORF_ID:nsp8450. (252 aa)
NSP_7800Parvulin-like peptidyl-prolyl isomerase; Nsp7800; ORF_ID:nsp7800. (260 aa)
NSP_6450Hypothetical protein; Nsp6450; ORF_ID:nsp6450. (259 aa)
NSP_47600AbrB family transciptional regulator; Nsp47600; ORF_ID:nsp47600. (137 aa)
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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