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EDM25839.1 EDM25839.1 trpC trpC EDM26552.1 EDM26552.1 EDM25000.1 EDM25000.1 EDM27467.1 EDM27467.1 aroE aroE aroE-2 aroE-2 trpA trpA trpB trpB trpD trpD aroA aroA aroC aroC aroK aroK EDM29427.1 EDM29427.1 EDM29502.1 EDM29502.1 hisC-2 hisC-2 trpE trpE trpF trpF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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EDM25839.1Chorismate mutase/prephenate dehydratase; COG1605 Chorismate mutase. (360 aa)
trpCCOG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa)
EDM26552.13-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (382 aa)
EDM25000.1COG0710 3-dehydroquinate dehydratase. (220 aa)
EDM27467.1COG0287 Prephenate dehydrogenase. (299 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (282 aa)
aroE-2Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (283 aa)
trpATryptophan synthase alpha subunit-like protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (256 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (415 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (424 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (370 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (176 aa)
EDM29427.1COG0512 Anthranilate/para-aminobenzoate synthases component II. (192 aa)
EDM29502.1Para-aminobenzoate synthetase, putative; COG0147 Anthranilate/para-aminobenzoate synthases component I. (581 aa)
hisC-2COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (514 aa)
trpFN-(5'phosphoribosyl)anthranilate isomerase (PRAI); COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (209 aa)
Your Current Organism:
Lentisphaera araneosa
NCBI taxonomy Id: 313628
Other names: L. araneosa HTCC2155, Lentisphaera araneosa HTCC2155, Lentisphaera araneosa str. HTCC2155, Lentisphaera araneosa strain HTCC2155
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