(55 nodes) Mixed, incl. Toxin-antitoxin system, RelE/ParE toxin domain superfamily, and Large family of predicted nucleotide-binding domains network (Lentisphaera araneosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EDM24686.1	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain. (127 aa)
	EDM24687.1	Transcriptional regulator, CopG family protein. (74 aa)
	EDM24688.1	Hypothetical protein. (98 aa)
	EDM24689.1	Hypothetical protein. (67 aa)
	EDM24962.1	Hypothetical protein. (37 aa)
	EDM24963.1	Hypothetical protein. (62 aa)
	EDM24964.1	Plasmid stabilization system; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system. (87 aa)
	EDM24891.1	Hypothetical protein. (285 aa)
	EDM24892.1	Hypothetical protein; COG1349 Transcriptional regulators of sugar metabolism. (292 aa)
	EDM24893.1	Hypothetical protein. (74 aa)
	EDM24894.1	Hypothetical protein; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system. (87 aa)
	EDM24895.1	Hypothetical protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis. (137 aa)
	EDM24896.1	Hypothetical protein. (132 aa)
	vapC	Virulence associated protein C; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (133 aa)
	EDM26870.1	COG4456 Virulence-associated protein and related proteins. (75 aa)
	EDM26871.1	Hypothetical protein. (90 aa)
	EDM26872.1	Hypothetical protein. (88 aa)
	EDM26873.1	Hypothetical protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (152 aa)
	EDM26875.1	COG0515 Serine/threonine protein kinase. (310 aa)
	EDM28627.1	COG4115 Uncharacterized protein conserved in bacteria. (87 aa)
	EDM28628.1	Putative antitoxin of toxin-antitoxin stability system; Antitoxin component of a type II toxin-antitoxin (TA) system. (80 aa)
	EDM28629.1	Hypothetical protein. (110 aa)
	EDM28630.1	Hypothetical protein. (247 aa)
	EDM28631.1	Hypothetical protein. (178 aa)
	EDM28777.1	Hypothetical protein. (180 aa)
	EDM28778.1	Hypothetical protein; COG5049 5'-3' exonuclease. (63 aa)
	EDM28779.1	Hypothetical protein; COG5340 Predicted transcriptional regulator. (197 aa)
	EDM28781.1	Hypothetical protein. (874 aa)
	EDM28782.1	Hypothetical protein. (275 aa)
	EDM28783.1	COG1094 Predicted RNA-binding protein (contains KH domains). (188 aa)
	EDM28784.1	Addiction module toxin, Txe/YoeB; COG4115 Uncharacterized protein conserved in bacteria. (87 aa)
	EDM28785.1	Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (108 aa)
	EDM28786.1	Hypothetical protein. (70 aa)
	EDM25394.1	Hypothetical protein. (279 aa)
	EDM25395.1	Hypothetical protein; COG5340 Predicted transcriptional regulator. (197 aa)
	EDM28535.1	COG0088 Ribosomal protein L4. (59 aa)
	EDM28536.1	Hypothetical protein. (152 aa)
	EDM28537.1	Hypothetical protein; COG5450 Transcription regulator of the Arc/MetJ class. (66 aa)
	vapC-2	PilT protein-like protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (129 aa)
	EDM28539.1	Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (83 aa)
	EDM28540.1	COG4115 Uncharacterized protein conserved in bacteria. (84 aa)
	EDM28541.1	COG3328 Transposase and inactivated derivatives. (388 aa)
	EDM28258.1	Hypothetical protein. (72 aa)
	EDM28259.1	COG2929 Uncharacterized protein conserved in bacteria. (94 aa)
	EDM28260.1	Hypothetical protein. (91 aa)
	EDM24826.1	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain. (126 aa)
	EDM24827.1	Transcriptional regulator, CopG family protein. (74 aa)
	EDM24828.1	COG3344 Retron-type reverse transcriptase. (107 aa)
	EDM27628.1	Hypothetical protein. (64 aa)
	EDM27629.1	Hypothetical protein. (115 aa)
	EDM25257.1	Hypothetical protein. (90 aa)
	EDM25258.1	Hypothetical protein; COG5611 Predicted nucleic-acid-binding protein, contains PIN domain. (132 aa)
	EDM25259.1	Transcriptional regulator, AbrB family protein; COG2002 Regulators of stationary/sporulation gene expression. (81 aa)
	EDM25260.1	Hypothetical protein. (49 aa)
	EDM25261.1	COG3328 Transposase and inactivated derivatives. (388 aa)

Your Current Organism:

Lentisphaera araneosa

NCBI taxonomy Id: 313628
Other names: L. araneosa HTCC2155, Lentisphaera araneosa HTCC2155, Lentisphaera araneosa str. HTCC2155, Lentisphaera araneosa strain HTCC2155

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDM24686.1	EDM24687.1	LNTAR_02564	LNTAR_02569	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	Transcriptional regulator, CopG family protein.	0.773
EDM24686.1	EDM24688.1	LNTAR_02564	LNTAR_02574	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	Hypothetical protein.	0.633
EDM24686.1	EDM24689.1	LNTAR_02564	LNTAR_02579	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	Hypothetical protein.	0.471
EDM24686.1	EDM25258.1	LNTAR_02564	LNTAR_24803	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	Hypothetical protein; COG5611 Predicted nucleic-acid-binding protein, contains PIN domain.	0.497
EDM24686.1	EDM26870.1	LNTAR_02564	LNTAR_06479	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	COG4456 Virulence-associated protein and related proteins.	0.830
EDM24686.1	EDM28259.1	LNTAR_02564	LNTAR_12921	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	COG2929 Uncharacterized protein conserved in bacteria.	0.435
EDM24686.1	vapC	LNTAR_02564	LNTAR_06474	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	Virulence associated protein C; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.	0.529
EDM24687.1	EDM24686.1	LNTAR_02569	LNTAR_02564	Transcriptional regulator, CopG family protein.	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	0.773
EDM24687.1	EDM24688.1	LNTAR_02569	LNTAR_02574	Transcriptional regulator, CopG family protein.	Hypothetical protein.	0.471
EDM24687.1	EDM24689.1	LNTAR_02569	LNTAR_02579	Transcriptional regulator, CopG family protein.	Hypothetical protein.	0.471
EDM24688.1	EDM24686.1	LNTAR_02574	LNTAR_02564	Hypothetical protein.	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	0.633
EDM24688.1	EDM24687.1	LNTAR_02574	LNTAR_02569	Hypothetical protein.	Transcriptional regulator, CopG family protein.	0.471
EDM24688.1	EDM24689.1	LNTAR_02574	LNTAR_02579	Hypothetical protein.	Hypothetical protein.	0.773
EDM24688.1	vapC	LNTAR_02574	LNTAR_06474	Hypothetical protein.	Virulence associated protein C; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.	0.452
EDM24689.1	EDM24686.1	LNTAR_02579	LNTAR_02564	Hypothetical protein.	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	0.471
EDM24689.1	EDM24687.1	LNTAR_02579	LNTAR_02569	Hypothetical protein.	Transcriptional regulator, CopG family protein.	0.471
EDM24689.1	EDM24688.1	LNTAR_02579	LNTAR_02574	Hypothetical protein.	Hypothetical protein.	0.773
EDM24826.1	EDM24827.1	LNTAR_15412	LNTAR_15417	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	Transcriptional regulator, CopG family protein.	0.773
EDM24826.1	EDM24828.1	LNTAR_15412	LNTAR_15422	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	COG3344 Retron-type reverse transcriptase.	0.497
EDM24826.1	EDM25258.1	LNTAR_15412	LNTAR_24803	PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.	Hypothetical protein; COG5611 Predicted nucleic-acid-binding protein, contains PIN domain.	0.482

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