Your Input: | |
| | EDM27874.1 | Adenylyl cyclase class-3/4/guanylyl cyclase; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. (373 aa) |
| | EDM27876.1 | COG0281 Malic enzyme. (459 aa) |
| | EDM27963.1 | COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (328 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (503 aa) |
| | EDM25049.1 | Two-component hybrid sensor and regulator; COG0784 FOG: CheY-like receiver. (176 aa) |
| | EDM26530.1 | Aldolase; COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes. (290 aa) |
| | trpC | COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa) |
| | EDM26552.1 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (382 aa) |
| | EDM26557.1 | Deoxyribodipyrimidine photolyase-like protein; COG0415 Deoxyribodipyrimidine photolyase. (365 aa) |
| | EDM26558.1 | COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (481 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (335 aa) |
| | EDM25110.1 | COG0498 Threonine synthase. (456 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (372 aa) |
| | EDM25222.1 | COG0315 Molybdenum cofactor biosynthesis enzyme. (150 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (882 aa) |
| | EDM25000.1 | COG0710 3-dehydroquinate dehydratase. (220 aa) |
| | gmd | GDP-D-mannose dehydratase in colanic acid gene cluster; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (372 aa) |
| | EDM26113.1 | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (229 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (343 aa) |
| | EDM27488.1 | COG0019 Diaminopimelate decarboxylase. (418 aa) |
| | psd | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (288 aa) |
| | EDM26461.1 | COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (206 aa) |
| | hisB | COG0131 Imidazoleglycerol-phosphate dehydratase. (194 aa) |
| | EDM26479.1 | Hypothetical protein. (141 aa) |
| | EDM26982.1 | Hypothetical protein. (186 aa) |
| | EDM25885.1 | Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (207 aa) |
| | EDM25889.1 | Hypothetical protein; COG1413 FOG: HEAT repeat. (550 aa) |
| | EDM25914.1 | Hypothetical protein; COG2319 FOG: WD40 repeat. (309 aa) |
| | EDM25943.1 | Probable d-serine deaminase (d-serine dehydratase) protein; COG3616 Predicted amino acid aldolase or racemase. (416 aa) |
| | EDM24972.1 | KDPG and KHG aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (205 aa) |
| | EDM24987.1 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. (271 aa) |
| | EDM24992.1 | Hypothetical protein. (320 aa) |
| | EDM25579.1 | Aconitate hydratase 2; COG1049 Aconitase B; Belongs to the aconitase/IPM isomerase family. (853 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (162 aa) |
| | EDM28581.1 | COG3046 Uncharacterized protein related to deoxyribodipyrimidine photolyase. (515 aa) |
| | EDM28582.1 | COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (429 aa) |
| | EDM28585.1 | Hypothetical protein; COG1520 FOG: WD40-like repeat. (317 aa) |
| | EDM28656.1 | COG4303 Ethanolamine ammonia-lyase, large subunit. (463 aa) |
| | EDM28657.1 | COG4302 Ethanolamine ammonia-lyase, small subunit; Belongs to the EutC family. (261 aa) |
| | EDM28695.1 | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. (631 aa) |
| | EDM28715.1 | COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis. (215 aa) |
| | EDM28316.1 | Cobalamin (vitamin B12) biosynthesis CbiX protein. (139 aa) |
| | ilvD | COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (614 aa) |
| | EDM28378.1 | Glutathione-dependent formaldehyde-activating, GFA. (140 aa) |
| | EDM28403.1 | COG0095 Lipoate-protein ligase A. (226 aa) |
| | EDM28442.1 | Hypothetical protein; COG2319 FOG: WD40 repeat. (303 aa) |
| | EDM28487.1 | Probable secreted glycosyl hydrolase. (223 aa) |
| | leuC | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (471 aa) |
| | leuD | COG0066 3-isopropylmalate dehydratase small subunit; Belongs to the LeuD family. (202 aa) |
| | EDM28555.1 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa) |
| | EDM28006.1 | Lyase containing HEAT-repeat; COG1413 FOG: HEAT repeat. (185 aa) |
| | EDM28007.1 | Hypothetical protein. (89 aa) |
| | trpA | Tryptophan synthase alpha subunit-like protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (256 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (415 aa) |
| | mqnA | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (271 aa) |
| | EDM28845.1 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase. (201 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (229 aa) |
| | EDM29022.1 | Transcriptional coactivator/pterin dehydratase; COG2154 Pterin-4a-carbinolamine dehydratase. (108 aa) |
| | gmd-2 | Subunit of GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (372 aa) |
| | EDM24703.1 | COG0422 Thiamine biosynthesis protein ThiC. (157 aa) |
| | EDM27081.1 | COG0422 Thiamine biosynthesis protein ThiC. (322 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (370 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (210 aa) |
| | hisF | Imidazole glycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (259 aa) |
| | EDM27188.1 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | EDM26136.1 | Lyase containing HEAT-repeat; COG1413 FOG: HEAT repeat. (272 aa) |
| | aroB | COG0337 3-dehydroquinate synthetase. (384 aa) |
| | EDM29521.1 | Adenylate cyclase, putative; COG1716 FOG: FHA domain. (313 aa) |
| | EDM29610.1 | Deoxyribodipyrimidine photolyase-like protein; COG0415 Deoxyribodipyrimidine photolyase. (359 aa) |
| | EDM29611.1 | COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (481 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (512 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (212 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (276 aa) |
| | EDM29720.1 | Hypothetical protein; COG2107 Predicted periplasmic solute-binding protein. (263 aa) |
| | EDM29725.1 | COG2721 Altronate dehydratase. (550 aa) |
| | EDM26667.1 | Hypothetical protein; Belongs to the LarC family. (476 aa) |
| | EDM26668.1 | Hypothetical protein; COG0019 Diaminopimelate decarboxylase. (389 aa) |
| | EDM26719.1 | Putative multi-domain protein. (272 aa) |
| | dacA | Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (284 aa) |
| | EDM26730.1 | Hypothetical protein; COG0720 6-pyruvoyl-tetrahydropterin synthase. (144 aa) |
| | EDM26738.1 | COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. (604 aa) |
| | EDM26023.1 | Hypothetical protein; COG2319 FOG: WD40 repeat. (309 aa) |
| | EDM26359.1 | COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase. (219 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | EDM26390.1 | Putative N-acetylneuraminate lyase (sialic acid lyase); COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase. (169 aa) |
| | EDM27577.1 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (474 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | EDM27625.1 | COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (373 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (514 aa) |
| | panD | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (119 aa) |
| | EDM27692.1 | Probable uroporphiryn-III C-methyltransferase/siroheme synthase; COG0007 Uroporphyrinogen-III methylase. (460 aa) |
| | EDM27712.1 | Probable secreted glycosyl hydrolase. (233 aa) |
| | EDM27307.1 | Probable secreted glycosyl hydrolase. (218 aa) |
| | EDM25379.1 | Putative large multi-functional protein. (219 aa) |
| | EDM29149.1 | COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases. (229 aa) |
| | EDM29157.1 | Putative large multi-functional protein. (342 aa) |
| | EDM29205.1 | Putative large, multifunctional secreted protein. (219 aa) |
| | EDM25542.1 | Amino-acid abc transporter binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. (488 aa) |
| | cynS | Cyanate lyase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (146 aa) |
| | EDM26262.1 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (537 aa) |
| | EDM25169.1 | COG0165 Argininosuccinate lyase. (431 aa) |
| | EDM25615.1 | COG0065 3-isopropylmalate dehydratase large subunit; Belongs to the aconitase/IPM isomerase family. (433 aa) |
| | EDM25616.1 | COG0066 3-isopropylmalate dehydratase small subunit; Belongs to the LeuD family. (183 aa) |
