STRINGSTRING
EDM25943.1 EDM25943.1 EDM26891.1 EDM26891.1 glyA-2 glyA-2 EDM26067.1 EDM26067.1 EDM25111.1 EDM25111.1 EDM25110.1 EDM25110.1 EDM25823.1 EDM25823.1 EDM25818.1 EDM25818.1 EDM24787.1 EDM24787.1 EDM26241.1 EDM26241.1 EDM26214.1 EDM26214.1 EDM29396.1 EDM29396.1 EDM29375.1 EDM29375.1 EDM27571.1 EDM27571.1 EDM26410.1 EDM26410.1 EDM26397.1 EDM26397.1 EDM26035.1 EDM26035.1 EDM26734.1 EDM26734.1 ilvA ilvA EDM29661.1 EDM29661.1 gcvH gcvH EDM29530.1 EDM29530.1 EDM29422.1 EDM29422.1 EDM27204.1 EDM27204.1 EDM28896.1 EDM28896.1 EDM25733.1 EDM25733.1 trpB trpB trpA trpA asd asd EDM28750.1 EDM28750.1 EDM28726.1 EDM28726.1 EDM28707.1 EDM28707.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDM25943.1Probable d-serine deaminase (d-serine dehydratase) protein; COG3616 Predicted amino acid aldolase or racemase. (416 aa)
EDM26891.1COG0515 Serine/threonine protein kinase. (362 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (504 aa)
EDM26067.1Transcriptional regulator, XRE family protein; COG0560 Phosphoserine phosphatase. (223 aa)
EDM25111.1COG0460 Homoserine dehydrogenase. (431 aa)
EDM25110.1COG0498 Threonine synthase. (456 aa)
EDM25823.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (309 aa)
EDM25818.1COG0527 Aspartokinases. (467 aa)
EDM24787.1Probable CDP-diacylglycerol--serine O-phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (311 aa)
EDM26241.1SerA; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (522 aa)
EDM26214.1Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (547 aa)
EDM29396.1Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (370 aa)
EDM29375.1COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain. (993 aa)
EDM27571.1COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. (375 aa)
EDM26410.1COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (342 aa)
EDM26397.1Putative 2-hydroxyacid-family dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (170 aa)
EDM26035.1Probable D-2-hydroxyacid dehydrogenase protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (331 aa)
EDM26734.1COG2833 Uncharacterized protein conserved in bacteria. (650 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (512 aa)
EDM29661.1COG0560 Phosphoserine phosphatase. (295 aa)
gcvHGlycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (120 aa)
EDM29530.1COG0006 Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. (432 aa)
EDM29422.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (371 aa)
EDM27204.1Hypothetical protein. (178 aa)
EDM28896.1COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family. (119 aa)
EDM25733.1Hypothetical protein; COG0819 Putative transcription activator. (226 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (415 aa)
trpATryptophan synthase alpha subunit-like protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (256 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (334 aa)
EDM28750.1Hypothetical protein. (273 aa)
EDM28726.1Phytanoyl-CoA dioxygenase; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin. (292 aa)
EDM28707.1COG0404 Glycine cleavage system T protein (aminomethyltransferase). (358 aa)
Your Current Organism:
Lentisphaera araneosa
NCBI taxonomy Id: 313628
Other names: L. araneosa HTCC2155, Lentisphaera araneosa HTCC2155, Lentisphaera araneosa str. HTCC2155, Lentisphaera araneosa strain HTCC2155
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