STRINGSTRING
EAS47559.1 EAS47559.1 EAS47661.1 EAS47661.1 bioA bioA EAS46722.1 EAS46722.1 EAS46804.1 EAS46804.1 EAS46805.1 EAS46805.1 bioD bioD bioD-2 bioD-2 bioC bioC bioF bioF bioB bioB EAS46812.1 EAS46812.1 EAS46856.1 EAS46856.1 EAS46957.1 EAS46957.1 panC panC panD panD tdh tdh kbl kbl EAS46207.1 EAS46207.1 nadE-2 nadE-2 panB panB EAS45932.1 EAS45932.1 coaX coaX birA birA EAS45935.1 EAS45935.1 EAS45936.1 EAS45936.1 coaD coaD EAS47976.1 EAS47976.1 EAS47241.1 EAS47241.1 EAS47292.1 EAS47292.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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EAS47559.1Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (354 aa)
EAS47661.1Probable aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (473 aa)
bioAPutative adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (432 aa)
EAS46722.1Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. (165 aa)
EAS46804.1Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. (304 aa)
EAS46805.1RecJ exonuclease; COG0608 Single-stranded DNA-specific exonuclease. (583 aa)
bioDDithiobiotin synthetase. (61 aa)
bioD-2Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (226 aa)
bioCProbable biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (531 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (391 aa)
bioBBiotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (372 aa)
EAS46812.1Hypothetical protein; COG1048 Aconitase A. (94 aa)
EAS46856.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (556 aa)
EAS46957.1Hypothetical protein. (304 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa)
panDAspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (341 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (396 aa)
EAS46207.1Hypothetical protein. (56 aa)
nadE-2NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (277 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (252 aa)
EAS45932.1Hypothetical protein. (159 aa)
coaXHypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (245 aa)
birAbirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. (336 aa)
EAS45935.1Hypothetical protein; COG0730 Predicted permeases. (265 aa)
EAS45936.1Hypothetical protein. (210 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
EAS47976.1Phosphopantothenoylcysteinedecarboxylase/phospho pantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (397 aa)
EAS47241.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (324 aa)
EAS47292.1COG0157 Nicotinate-nucleotide pyrophosphorylase. (370 aa)
Your Current Organism:
gamma proteobacterium HTCC2207
NCBI taxonomy Id: 314287
Other names: g. proteobacterium HTCC2207, marine gamma proteobacterium HTCC2207
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