STRINGSTRING
rnfE rnfE EDQ01362.1 EDQ01362.1 EDQ01360.1 EDQ01360.1 EDQ01358.1 EDQ01358.1 EDQ01355.1 EDQ01355.1 MioC MioC EDP99860.1 EDP99860.1 EDP99858.1 EDP99858.1 CoxN CoxN EDP99856.1 EDP99856.1 EDP99855.1 EDP99855.1 FrdC-2 FrdC-2 FrdC FrdC EDQ02603.1 EDQ02603.1 EDP99288.1 EDP99288.1 EDP99285.1 EDP99285.1 EDP99282.1 EDP99282.1 EDP99154.1 EDP99154.1 EDQ01282.1 EDQ01282.1 EDP99951.1 EDP99951.1 EDP99950.1 EDP99950.1 NifJ NifJ EDQ01644.1 EDQ01644.1 CydA CydA CydB CydB EDQ00739.1 EDQ00739.1 Fdx Fdx nuoN nuoN NuoM NuoM NuoL NuoL nuoK nuoK EDP99432.1 EDP99432.1 EDP99429.1 EDP99429.1 NuoF NuoF EDP99427.1 EDP99427.1 nuoC nuoC nuoB nuoB NuoA NuoA EDP99350.1 EDP99350.1 GrxA GrxA EDP99676.1 EDP99676.1 CcoN CcoN EDQ02296.1 EDQ02296.1 CcoP CcoP EDQ02227.1 EDQ02227.1 EDQ02226.1 EDQ02226.1 EDQ02194.1 EDQ02194.1 FldA FldA EDP99539.1 EDP99539.1 rnfA rnfA rnfB rnfB rnfC rnfC rnfD rnfD rnfG rnfG EDQ01364.1 EDQ01364.1 msrQ msrQ napA napA EDQ00406.1 EDQ00406.1 EDQ00405.1 EDQ00405.1 EDQ00404.1 EDQ00404.1 EDQ00403.1 EDQ00403.1 dsbB dsbB EDP98943.1 EDP98943.1 EDP98942.1 EDP98942.1 EDP99078.1 EDP99078.1 sdhB sdhB sdhA sdhA NrdG NrdG EDP98965.1 EDP98965.1 EDQ00374.1 EDQ00374.1 PetC PetC PetB PetB PetA PetA EDQ02772.1 EDQ02772.1 EDQ02771.1 EDQ02771.1 EDQ02753.1 EDQ02753.1 EtfA EtfA EtfB EtfB nqrF nqrF nqrE nqrE nqrB nqrB YceJ YceJ EDQ00617.1 EDQ00617.1 EDQ00616.1 EDQ00616.1 HemG HemG EDP99582.1 EDP99582.1 Cc Cc EDQ02392.1 EDQ02392.1 FrdA FrdA FrdB FrdB EDQ00094.1 EDQ00094.1 NorV NorV dsbD dsbD EDQ02128.1 EDQ02128.1 EDQ02129.1 EDQ02129.1 nqrB-2 nqrB-2 nqrE-2 nqrE-2 nqrF-2 nqrF-2 CtaD CtaD EDQ02389.1 EDQ02389.1 EDQ01374.1 EDQ01374.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rnfENADH-ubiquinone oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (256 aa)
EDQ01362.1Formate dehydrogenase, alpha subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (951 aa)
EDQ01360.1Formate dehydrogenase, C subunit, putative; COG2864 Cytochrome b subunit of formate dehydrogenase. (341 aa)
EDQ01358.1Formate dehydrogenase, alpha subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (949 aa)
EDQ01355.1Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. (561 aa)
MioCCOG0716 Flavodoxins. (146 aa)
EDP99860.1Hypothetical protein. (185 aa)
EDP99858.1COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2. (495 aa)
CoxNCOG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family. (584 aa)
EDP99856.1COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3. (230 aa)
EDP99855.1Probable cytochrome-C oxidase subunit III oxidoreductase protein; COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3. (230 aa)
FrdC-2COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (238 aa)
FrdCCOG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (243 aa)
EDQ02603.1COG3672 Predicted periplasmic protein. (235 aa)
EDP99288.1Hypothetical tetrathionate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1011 aa)
EDP99285.1Putative molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (714 aa)
EDP99282.1Formate dehydrogenase, C subunit, putative; COG2864 Cytochrome b subunit of formate dehydrogenase. (321 aa)
EDP99154.1COG3245 Cytochrome c5. (97 aa)
EDQ01282.1trimethylamine-N-oxide reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (830 aa)
EDP99951.1COG2025 Electron transfer flavoprotein, alpha subunit. (315 aa)
EDP99950.1COG2086 Electron transfer flavoprotein, beta subunit. (257 aa)
NifJCOG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (1201 aa)
EDQ01644.1Polyhedral body protein; COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC. (456 aa)
CydACOG1271 Cytochrome bd-type quinol oxidase, subunit 1. (518 aa)
CydBCOG1294 Cytochrome bd-type quinol oxidase, subunit 2. (379 aa)
EDQ00739.1Hypothetical protein; COG4890 Predicted outer membrane lipoprotein. (38 aa)
FdxFerredoxin, 2Fe-2S; COG0633 Ferredoxin. (112 aa)
nuoNNADH dehydrogenase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (475 aa)
NuoMCOG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M). (532 aa)
NuoLCOG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit. (629 aa)
nuoKNADH dehydrogenase kappa subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
EDP99432.1NADH-ubiquinone/plastoquinone oxidoreductase, chain 6; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (208 aa)
EDP99429.1NADH dehydrogenase gamma subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (960 aa)
NuoFNADH dehydrogenase I, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (458 aa)
EDP99427.1ATP synthase subunit E; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. (178 aa)
nuoCNADH dehydrogenase I, C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (596 aa)
nuoBNADH dehydrogenase beta subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (218 aa)
NuoANADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. (123 aa)
EDP99350.1COG2010 Cytochrome c, mono- and diheme variants. (410 aa)
GrxACOG0695 Glutaredoxin and related proteins. (108 aa)
EDP99676.1Hypothetical protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (77 aa)
CcoNCOG3278 Cbb3-type cytochrome oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family. (474 aa)
EDQ02296.1COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit. (208 aa)
CcoPCytochrome c oxidase, cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (322 aa)
EDQ02227.1Hypothetical protein. (76 aa)
EDQ02226.1COG2871 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF. (316 aa)
EDQ02194.1Iron-sulfur cluster-binding protein; COG0633 Ferredoxin. (124 aa)
FldAFlavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (176 aa)
EDP99539.1Cytochrome b, putative; COG3658 Cytochrome b. (246 aa)
rnfANa(+)-translocating NADH-quinone reductase subunit E; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (192 aa)
rnfBElectron transport complex protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (189 aa)
rnfCElectron transport complex protein RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (620 aa)
rnfDHypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (350 aa)
rnfGElectron transport complex protein RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (212 aa)
EDQ01364.1Formate dehydrogenase, C subunit, putative; COG2864 Cytochrome b subunit of formate dehydrogenase. (328 aa)
msrQHypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the [...] (218 aa)
napAAnaerobic dehydrogenase, typically selenocysteine-containing; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (829 aa)
EDQ00406.1Quinone-reactive Ni/Fe hydrogenase, small subunit precursor; COG1740 Ni,Fe-hydrogenase I small subunit. (378 aa)
EDQ00405.1Quinone-reactive Ni/Fe hydrogenase, large subunit; COG0374 Ni,Fe-hydrogenase I large subunit. (410 aa)
EDQ00404.1Quinone-reactive Ni/Fe hydrogenase, large subunit; COG0374 Ni,Fe-hydrogenase I large subunit. (171 aa)
EDQ00403.1COG1969 Ni,Fe-hydrogenase I cytochrome b subunit. (221 aa)
dsbBDisulfide bond formation protein b; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (176 aa)
EDP98943.1COG0426 Uncharacterized flavoproteins. (147 aa)
EDP98942.1COG0426 Uncharacterized flavoproteins. (98 aa)
EDP99078.1Hypothetical protein; COG0437 Fe-S-cluster-containing hydrogenase components 1. (697 aa)
sdhBCOG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (235 aa)
sdhACOG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
NrdGAnaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (157 aa)
EDP98965.1COG1858 Cytochrome c peroxidase. (329 aa)
EDQ00374.1Hypothetical protein; COG1454 Alcohol dehydrogenase, class IV. (176 aa)
PetCCOG2857 Cytochrome c1. (240 aa)
PetBUbiquinol-cytochrome c reductase, cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (404 aa)
PetAUbiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (196 aa)
EDQ02772.1Putative suppressor for copper-sensitivity B precursor; COG4232 Thiol:disulfide interchange protein. (245 aa)
EDQ02771.1Putative suppressor for copper-sensitivity B precursor; COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis. (283 aa)
EDQ02753.1Azurin precursor; Transfers electrons from cytochrome c551 to cytochrome oxidase. (161 aa)
EtfACOG2025 Electron transfer flavoprotein, alpha subunit. (307 aa)
EtfBCOG2086 Electron transfer flavoprotein, beta subunit. (249 aa)
nqrFNa(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (405 aa)
nqrENADH:ubiquinone oxidoreductase, Na translocating, hydrophobic membrane protein NqrE; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (202 aa)
nqrBNa(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (415 aa)
YceJCOG3038 Cytochrome B561. (182 aa)
EDQ00617.1COG3909 Cytochrome c556. (153 aa)
EDQ00616.1B-type cytochrome, putative; COG3658 Cytochrome b. (204 aa)
HemGCOG4635 Flavodoxin. (175 aa)
EDP99582.1Protoporphyrinogen oxidase, putative; COG4635 Flavodoxin. (179 aa)
CcCOG2863 Cytochrome c553. (206 aa)
EDQ02392.1COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3. (291 aa)
FrdAFumarate reductase; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (670 aa)
FrdBCOG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (247 aa)
EDQ00094.1Anaerobic nitric oxide reductase flavorubredoxin; COG0426 Uncharacterized flavoproteins. (158 aa)
NorVAnaerobic nitric oxide reductase flavorubredoxin; COG0426 Uncharacterized flavoproteins. (339 aa)
dsbDThiol:disulfide interchange protein precursor; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (621 aa)
EDQ02128.1Hypothetical protein; COG4635 Flavodoxin. (175 aa)
EDQ02129.1Hypothetical protein. (178 aa)
nqrB-2Na(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (399 aa)
nqrE-2NADH:ubiquinone oxidoreductase, Na translocating, hydrophobic membrane protein NqrE; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (202 aa)
nqrF-2Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (415 aa)
CtaDCytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (541 aa)
EDQ02389.1Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (352 aa)
EDQ01374.1Electron transfer flavoprotein-ubiquinone oxidoreductase, putative; Accepts electrons from ETF and reduces ubiquinone. (549 aa)
Your Current Organism:
Shewanella benthica
NCBI taxonomy Id: 314608
Other names: S. benthica KT99, Shewanella benthica KT99, Shewanella benthica str. KT99, Shewanella benthica strain KT99
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