STRINGSTRING
RF_0579 RF_0579 nuoA nuoA nuoB nuoB nuoC nuoC RF_0544 RF_0544 bioY1 bioY1 aprD aprD proP2 proP2 tolR tolR atrC1 atrC1 RF_0452 RF_0452 RF_0441 RF_0441 RF_0439 RF_0439 corA corA aas aas RF_0397 RF_0397 proP proP bcr1 bcr1 abcT3 abcT3 RF_0322 RF_0322 RF_0309 RF_0309 ampG2 ampG2 proP4 proP4 msbA2 msbA2 bcr2 bcr2 ccmF ccmF proP10 proP10 tlc5 tlc5 RF_0132 RF_0132 tlc1 tlc1 uhpC uhpC secG secG RF_0066 RF_0066 proP1 proP1 RF_0053 RF_0053 atpB atpB atpE atpE atpF atpF rfbE rfbE tlc4 tlc4 bioY2 bioY2 RF_0814 RF_0814 ampG1 ampG1 tlc3 tlc3 potE potE nuoN1 nuoN1 RF_0862 RF_0862 proP8 proP8 RF_0894 RF_0894 panF panF secA secA mgtE mgtE RF_0955 RF_0955 secD secD mviN mviN RF_0970 RF_0970 mdlB mdlB tolC tolC petB petB petA petA ccmB ccmB RF_1014 RF_1014 atm1 atm1 coxC coxC gltP gltP acrF acrF emrB emrB mnhE mnhE yqiX yqiX secE secE yqiY yqiY nuoF nuoF secF secF tatA tatA proP5 proP5 RF_1217 RF_1217 RF_1219 RF_1219 ampG3 ampG3 tatC tatC nuoJ nuoJ nuoL1 nuoL1 nuoM nuoM ccmA ccmA nuoG nuoG atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH kefB kefB ccmC ccmC RF_1320 RF_1320 znuC znuC RF_1327 RF_1327 proP6 proP6 pntA1 pntA1 glnQ glnQ proP7 proP7 proP3 proP3 tlc2 tlc2 RF_0598 RF_0598 msbA1 msbA1 ampG4 ampG4 RF_0614 RF_0614 coxA coxA coxB coxB RF_0639 RF_0639 RF_0640 RF_0640 RF_0641 RF_0641 mfp mfp RF_0643 RF_0643 RF_0705 RF_0705 RF_0706 RF_0706
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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RF_0579ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (277 aa)
nuoANADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (123 aa)
nuoBNADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (174 aa)
nuoCNADH dehydrogenase I chain C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (207 aa)
RF_0544Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (331 aa)
bioY1BioY family protein. (194 aa)
aprDAlkaline protease secretion ATP-binding protein AprD; ABC transporter. (584 aa)
proP2MFS type sugar transporter PFAM00083. (438 aa)
tolRTolR protein. (143 aa)
atrC1Cationic amino acid transporter-1. (465 aa)
RF_0452MFS type sugar transporter; PFAM00083. (240 aa)
RF_0441MFS type sugar transporter; PFAM00083. (435 aa)
RF_0439MFS type sugar transporter; PFAM00083. (435 aa)
corAMagnesium and cobalt transport protein CorA. (319 aa)
aas2-acylglycerophosphoethanolamine acyltransferase. (1140 aa)
RF_0397MFS type sugar transporter; PFAM00083. (276 aa)
proPPermeases of the major facilitator superfamily. (397 aa)
bcr1Bicyclomycin resistance protein; MFS type drug exporter. (405 aa)
abcT3Multidrug resistance ABC transporter ATP-binding protein. (589 aa)
RF_0322Transporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (382 aa)
RF_0309MFS type sugar transporter; PFAM00083. (425 aa)
ampG2AmpG protein. (319 aa)
proP4MFS type sugar transporter PFAM00083. (464 aa)
msbA2Multidrug resistance protein; Part of an ABC transporter complex. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity). (581 aa)
bcr2Bicyclomycin resistance protein; MFS type drug exporter. (391 aa)
ccmFCytochrome c-type biogenesis protein CcmF. (673 aa)
proP10MFS type sugar transporter PFAM00083. (436 aa)
tlc5ADP,ATP carrier protein; Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity); Belongs to the ADP/ATP translocase tlc family. (499 aa)
RF_0132Conserved hypothetical membrane protein; Similar to small-conductance mechanosensitive channel. (388 aa)
tlc1ADP,ATP carrier protein; Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity); Belongs to the ADP/ATP translocase tlc family. (498 aa)
uhpCSugar phosphate permease; COG2271. (429 aa)
secGProtein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. (100 aa)
RF_0066Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (223 aa)
proP1MFS type sugar transporter PFAM00083. (418 aa)
RF_0053Putative surface antigen. (439 aa)
atpBATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (242 aa)
atpEATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa)
atpFATP synthase B chain precursor; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (164 aa)
rfbEO-antigen export system ATP-binding protein RfbE. (247 aa)
tlc4ADP,ATP carrier protein; Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity); Belongs to the ADP/ATP translocase tlc family. (511 aa)
bioY2BioY family protein. (190 aa)
RF_0814Na+/proline symporter and signal transduction histidine kinase; Sodium:solute symporter family, SSF; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (574 aa)
ampG1AmpG-related permease. (441 aa)
tlc3ADP,ATP carrier protein; Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity); Belongs to the ADP/ATP translocase tlc family. (501 aa)
potEPutrescine-ornithine antiporter. (427 aa)
nuoN1NADH:ubiquinone oxidoreductase subunit 2 (chain N); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (458 aa)
RF_0862Putative to amino acid permeases. (399 aa)
proP8MFS type sugar transporter PFAM00083. (451 aa)
RF_0894Multisubunit Na+/H+ antiporter, MnhF subunit. (100 aa)
panFSodium/pantothenate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (478 aa)
secAPreprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (906 aa)
mgtEMagnesium transporter; Acts as a magnesium transporter. (456 aa)
RF_0955MFS type sugar transporter PFAM00083. (154 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (518 aa)
mviNIntegral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (556 aa)
RF_0970Na+/proline symporter, signal transduction histidine kinase. (984 aa)
mdlBABC-type multidrug transport system, ATPase and permease components. (627 aa)
tolCType I secretion outer membrane protein, TolC family. (454 aa)
petBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (398 aa)
petAUbiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis; Belongs to the Rieske iron-sulfur protein family. (177 aa)
ccmBHeme exporter protein B. (215 aa)
RF_1014Monovalent cation/proton antiporter, MnhG/PhaG subunit. (122 aa)
atm1Multidrug resistance protein Atm1. (600 aa)
coxCCytochrome c oxidase subunit III. (278 aa)
gltPNa+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (399 aa)
acrFHydrophobe/amphiphile efflux-1 HAE1 family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1008 aa)
emrBMultidrug resistance protein B; MFS type drug exporter; Belongs to the major facilitator superfamily. (519 aa)
mnhEMultisubunit Na+/H+ antiporter, MnhE subunit. (107 aa)
yqiXAmino acid ABC transporter substrate binding protein. (241 aa)
secEPreprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (98 aa)
yqiYAmino acid ABC transporter permease protein; Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily. (218 aa)
nuoFNADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. (422 aa)
secFProtein-export membrane protein secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (308 aa)
tatATwin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (54 aa)
proP5MFS type sugar transporter PFAM00083. (423 aa)
RF_1217Unknown. (234 aa)
RF_1219Multidrug resistance transporter protein. (111 aa)
ampG3AmpG protein. (421 aa)
tatCSec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (251 aa)
nuoJNADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (205 aa)
nuoL1NADH dehydrogenase I chain L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (645 aa)
nuoMNADH dehydrogenase I chain M; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (493 aa)
ccmAHeme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (241 aa)
nuoGNADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 75 kDa subunit family. (671 aa)
atpCATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (112 aa)
atpDATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (508 aa)
atpGATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (288 aa)
atpAATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (510 aa)
atpHATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (184 aa)
kefBGlutathione-regulated potassium-efflux system protein KefB; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (575 aa)
ccmCHeme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (230 aa)
RF_1320Cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (306 aa)
znuCZinc ABC transporter ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (233 aa)
RF_1327MFS type sugar transporter; PFAM00083. (307 aa)
proP6MFS type sugar transporter PFAM00083. (415 aa)
pntA1NAD(P) transhydrogenase subunit alpha. (374 aa)
glnQGlutamine ABC transporter ATP-binding protein. (240 aa)
proP7MFS type sugar transporter PFAM00083. (423 aa)
proP3MFS type sugar transporter PFAM00083. (406 aa)
tlc2ADP,ATP carrier protein; Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity); Belongs to the ADP/ATP translocase tlc family. (507 aa)
RF_0598Unknown. (526 aa)
msbA1Multidrug resistance protein. (587 aa)
ampG4AmpG protein. (414 aa)
RF_0614FTR1 family protein. (282 aa)
coxACytochrome c oxidase polypeptide I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity). (532 aa)
coxBCytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity). (315 aa)
RF_0639RND family efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (486 aa)
RF_0640RND family efflux transporter. (241 aa)
RF_0641RND family efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (331 aa)
mfpMembrane-fusion protein component of the RND family transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (419 aa)
RF_0643RND efflux system, outer membrane protein. (463 aa)
RF_0705P pilus assembly protein FimD; Porin PapC; fimbrial Usher protein. (284 aa)
RF_0706P pilus assembly protein FimD; Porin PapC (fimbrial Usher protein). (510 aa)
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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