STRINGSTRING
RF_0009 RF_0009 RF_0011 RF_0011 pcnB pcnB RF_0023 RF_0023 RF_0025 RF_0025 RF_0026 RF_0026 recF recF RF_0050 RF_0050 sam sam rpsB rpsB RF_0075 RF_0075 rpmB rpmB rpmE rpmE argB argB ackA ackA rplS rplS parB parB pgsA pgsA RF_0134 RF_0134 rplI rplI rpsR rpsR rpsF rpsF aco1 aco1 phbB phbB surf1 surf1 dnaQ dnaQ rnhA rnhA RF_0181 RF_0181 himA himA RF_0206 RF_0206 RF_0221 RF_0221 ubiA ubiA RF_0263 RF_0263 RF_0264 RF_0264 RF_0267 RF_0267 rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsN rpsN rpsH rpsH rplF rplF rplR rplR rpsE rpsE rpmD rpmD rplO rplO adk adk rpsM rpsM rpsK rpsK rplQ rplQ rpsT rpsT RF_0306 RF_0306 RF_0314 RF_0314 n2B n2B RF_0344 RF_0344 rpmH rpmH rplT rplT rpmI rpmI rplY rplY ychF ychF dnaA dnaA RF_0366 RF_0366 spoT13 spoT13 RF_0388 RF_0388 RF_0400 RF_0400 RF_0411 RF_0411 RF_0416 RF_0416 accC accC rpsU rpsU RF_0428 RF_0428 RF_0437 RF_0437 RF_0444 RF_0444 cox11 cox11 RF_0506 RF_0506 bioB bioB RF_0535 RF_0535 RF_0546 RF_0546 RF_0547 RF_0547 rpsD rpsD nuoD nuoD RF_0580 RF_0580 RF_0597 RF_0597 RF_0644 RF_0644 recR recR tdcB tdcB yhbH yhbH rpsO rpsO addA addA ppdK ppdK RF_0742 RF_0742 RF_0743 RF_0743 himD himD rpsA rpsA fni fni rpmJ rpmJ bioC bioC RF_0810 RF_0810 plsC plsC iscS iscS spl1 spl1 priA priA ubiX ubiX dnaB dnaB recO recO RF_0870 RF_0870 infB infB nusA nusA RF_0922 RF_0922 RF_0923 RF_0923 RF_0949 RF_0949 RF_0950 RF_0950 mgtE mgtE RF_0977 RF_0977 rplM rplM rpsI rpsI hspC2 hspC2 hspC1 hspC1 pdhA pdhA rluA1 rluA1 coxW coxW bolA1 bolA1 atm1 atm1 fdxB fdxB recN recN queD queD RF_1099 RF_1099 hemN hemN hupA hupA RF_1117 RF_1117 rplL rplL rplJ rplJ nusG nusG rpsG rpsG rpsL rpsL sdhA sdhA RF_1170 RF_1170 RF_1175 RF_1175 tlyC tlyC ybeY ybeY nth nth rplU rplU rpmA rpmA RF_1202 RF_1202 RF_1203 RF_1203 fabG fabG rpmF rpmF bolA2 bolA2 RF_1306 RF_1306 fic fic radC radC tadA tadA RF_1320 RF_1320 truA truA dnaG dnaG sec59 sec59 RF_1365 RF_1365 phnP phnP rpsP rpsP rpmG rpmG RF_1389 RF_1389 RF_1390 RF_1390 hemH hemH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RF_0009Predicted esterase of the alpha-beta hydrolase superfamily. (246 aa)
RF_0011Ankyrin repeat. (325 aa)
pcnBPoly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (385 aa)
RF_0023Unknown. (106 aa)
RF_0025Unknown. (232 aa)
RF_0026TPR repeats. (549 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (420 aa)
RF_0050Transposition helper protein, OrfB. (266 aa)
samS-adenosylmethionine transporter; Transports S-adenosylmethionine; Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family. (294 aa)
rpsB30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (295 aa)
RF_0075Unknown. (334 aa)
rpmB50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (97 aa)
rpmE50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (78 aa)
argBAcetylglutamate kinase. (307 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (407 aa)
rplS50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (138 aa)
parBParB-like partition proteins; Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity). (286 aa)
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (181 aa)
RF_0134Uncharacterized conserved protein. (407 aa)
rplI50S ribosomal protein L9; Binds to the 23S rRNA. (171 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (95 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (129 aa)
aco1Acyl-CoA desaturase 1. (397 aa)
phbBAcetoacetyl-CoA reductase. (241 aa)
surf1Surfeit locus protein 1. (226 aa)
dnaQDNA polymerase III epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease (By similarity). (229 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (152 aa)
RF_0181Unknown. (99 aa)
himAIntegration host factor alpha-subunit; Belongs to the bacterial histone-like protein family. (95 aa)
RF_0206Unknown. (744 aa)
RF_0221Putative oxidoreductase protein. (431 aa)
ubiA4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (280 aa)
RF_0263ATP-dependent RNA helicase RhlE. (78 aa)
RF_0264ATP-dependent RNA helicase RhlE. (353 aa)
RF_0267NifU-like domain. (190 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (105 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (215 aa)
rplD50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (207 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (98 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa)
rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplV50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (119 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (217 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa)
rpmC50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (71 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (82 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplX50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (109 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rpsN30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (118 aa)
rpsE30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (176 aa)
rpmD50S ribosomal protein L30. (74 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (153 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (125 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (127 aa)
rplQ50S ribosomal protein L17. (126 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (90 aa)
RF_0306Transposition helper protein, OrfB. (266 aa)
RF_0314Ankyrin repeat. (227 aa)
n2BPutative ATPase n2B. (350 aa)
RF_0344Transposition helper protein, OrfB. (266 aa)
rpmH50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa)
rpmI50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (68 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (203 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (365 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (463 aa)
RF_0366Unknown. (87 aa)
spoT13Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog; Containing ankyrin repeat. (1179 aa)
RF_0388Transposition helper protein, OrfB. (266 aa)
RF_0400DnaA-like protein; ATPase involved in DNA replication initiation; Belongs to the DnaA family. (222 aa)
RF_0411Chitinase. (442 aa)
RF_0416Unknown. (111 aa)
accCAcetyl-CoA carboxylase, biotin carboxylase. (665 aa)
rpsU30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (66 aa)
RF_0428Acetyltransferase; Aminoglycoside phosphotransferase family. (291 aa)
RF_0437Transposition helper protein, OrfB. (266 aa)
RF_0444TPR repeats. (349 aa)
cox11Cytochrome c oxidase assembly protein cox11; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. (187 aa)
RF_0506Periplasmic protein TonB; Linking inner and outer membranes. (327 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (309 aa)
RF_0535Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (154 aa)
RF_0546Predicted hydrolases or acyltransferases. (252 aa)
RF_0547Glycosyltransferase. (390 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (221 aa)
nuoDNADH dehydrogenase I chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (391 aa)
RF_0580Ankyrin repeat. (305 aa)
RF_0597Alkylated DNA repair protein. (188 aa)
RF_0644Glycosyltransferase. (338 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (207 aa)
tdcBThreonine dehydratase. (333 aa)
yhbHProbable sigma(54) modulation protein. (192 aa)
rpsO30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (91 aa)
addAErythrocyte adducin alpha subunit. (99 aa)
ppdKPyruvate,phosphate dikinase precursor; Catalyzes the reversible phosphorylation of pyruvate and phosphate; Belongs to the PEP-utilizing enzyme family. (878 aa)
RF_0742Predicted esterase of the alpha-beta hydrolase superfamily. (122 aa)
RF_0743Predicted esterase of the alpha-beta hydrolase superfamily. (370 aa)
himDIntegration host factor beta-subunit; Belongs to the bacterial histone-like protein family. (80 aa)
rpsA30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity). (568 aa)
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (345 aa)
rpmJ50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (41 aa)
bioCBiotin synthesis protein BioC. (276 aa)
RF_0810Uncharacterized conserved protein. (292 aa)
plsC1-acyl-sn-glycerol-3-phosphate acyltransferase. (241 aa)
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (422 aa)
spl1Nifs protein homolog. (369 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (648 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (191 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (494 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (237 aa)
RF_0870Unknown. (439 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (829 aa)
nusAN utilization substance protein A, transcription termination factor NusA; Participates in both transcription termination and antitermination. (503 aa)
RF_0922Ankyrin repeat. (179 aa)
RF_0923Ankyrin repeat. (311 aa)
RF_0949Predicted glutamine amidotransferases. (134 aa)
RF_0950Ankyrin repeat; Partial match with predicted glutamine amidotransferases, COG2071. (395 aa)
mgtEMagnesium transporter; Acts as a magnesium transporter. (456 aa)
RF_0977Transposition helper protein, OrfB. (266 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (155 aa)
rpsI30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (161 aa)
hspC2Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. (154 aa)
hspC1Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. (146 aa)
pdhAPyruvate dehydrogenase e1 component, alpha subunit precursor; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (326 aa)
rluA1Ribosomal large subunit pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. (305 aa)
coxWCytochrome c oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (337 aa)
bolA1BolA protein homolog; Stress-induced morphogen; Belongs to the BolA/IbaG family. (80 aa)
atm1Multidrug resistance protein Atm1. (600 aa)
fdxBFerredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family. (112 aa)
recNDNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (546 aa)
queD6-pyruvoyl tetrahydropterin synthase; Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. (138 aa)
RF_1099Ankyrin repeat. (267 aa)
hemNProbable oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (386 aa)
hupADNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. (110 aa)
RF_1117Unknown. (392 aa)
rplL50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (125 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (169 aa)
nusGTranscription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (192 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (159 aa)
rpsL30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (150 aa)
sdhASuccinate dehydrogenase flavoprotein subunit. (596 aa)
RF_1170Unknown. (394 aa)
RF_1175TPR repeats. (148 aa)
tlyCHemolysin C; Belongs to the UPF0053 family. Hemolysin C subfamily. (299 aa)
ybeYConserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (167 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (213 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (105 aa)
rpmA50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (86 aa)
RF_1202Unknown. (136 aa)
RF_1203Unknown; Partial similarity to Predicted Zn-dependent hydrolases of the beta-lactamase fold, COG2220. (170 aa)
fabG3-oxoacyl reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (241 aa)
rpmF50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (66 aa)
bolA2BolA protein homolog; Stress-induced morphogen; Belongs to the BolA/IbaG family. (79 aa)
RF_1306Ankyrin repeat. (380 aa)
ficFic; Cd01108, HTH_CueR; cell filamentation proteins with Helix-turn-helix transcription regulator CueR. (324 aa)
radCDNA repair protein RadC. (155 aa)
tadACytosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (159 aa)
RF_1320Cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (306 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (245 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (595 aa)
sec59Dolichol kinase. (204 aa)
RF_1365Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (107 aa)
phnPMetal-dependent hydrolases of the beta-lactamase superfamily I. (254 aa)
rpsP30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (111 aa)
rpmG50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (56 aa)
RF_1389Oxidoreductase. (130 aa)
RF_1390Oxidoreductase. (101 aa)
hemHProbable ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (348 aa)
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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